This is not medical advice. I am posting this for educational and informational purposes. It takes time, persistence and research to heal.
Fibrosis can result in excess blood clotting, muscle damage, NAFLD, COPD and many other illness. I have posted on oxidative stress, inflammation and infection. I have also posted on toxins like glyphosate, glufosinate, mercury and detoxing them. All those things can cause fibrosis. Modern medicine looks at the symptoms and not the cause for example when the liver or lungs are failing they view those as the problem but most things like that are from a systemic failure throughout the body caused by many things. If you read my post it is your gut and not your genes you will see many things they blame on genetics can be corrected in the gut. Even thought this post is about NAFLD these things should help with just about any illness caused by fibrosis including thrombosis (blood clotting) because many of them have similar causes.
Ways NAFLD developes
Genes and NAFLD, keep in mind things they thought were genetic and could not be changed they have found can be and people can heal.
Good list of supplements for NAFLD.
Foods that may help.
Krill Oil and other fats may help with fatty liver.
Pantethine has been shown to reverse fatty liver disease. but excessive use may cause fatty liver.
Ubiquinol helps reduce fatty liver.
Low P5P can cause fatty liver disease.
PPC may help with fatty liver.
SAM helps with fatty liver.
Carnitine helps with fatty liver.
Those with fatty liver have been found to be low in magnesium. This can be cause by oxidative stress, inflammation , toxins and metabolic disorders.
Fruit vinegars help with fatty liver.
Alpha R-lipoic Acid helps with fatty liver.
Treatment options for NAFLD.
Nattokinase also reduces fibrinogen which would help with COPD and NAFLD.
This is a site with a list of things that can cause NAFLD. Most of these issues I have posted on if you search my blog.
Renal function can improve at any stage of illness.
In some Tenascan-C becomes activated which can lead to fibrosis throughout the body including the liver and lungs.
Illnesses that cause damage to the body from increased inflammation and oxidative stress can cause raised Tenascan-C levels.
Tenascin-C is high in tissue injury which is why it is important to address the issues that are causing the injury. Whether it is metabolic issues, nutrient deficiencies, toxins , infection or oxidative stress.
Ace inhibitors may help with fatty liver. I have posted on natural ACE inhibitors in my hypertension post.
Vitamin E found in things like Olive Oil and Fish Oil helps with fatty liver.
Vitamin D deficiency or a number of metabolic disorders or toxins can prevent the body from converting vitamin D to D3. Low levels of D3 can increase Tenascan-C levels. Supplementing with D3 may reduce Tenascan-C levels.
Alcoholics get cirrhosis of the liver because it depletes the nutrients (cofactors) needed for sulfation and glucuronidation.
Cholesterol dysregulation and NAFLD.
Betaine, Homocysteine, NAFLD.
Those who have issues with thiols cannot take betaine. I have posted on thiols.
Estrogen,PEMT and choline deficiency.
Choline deficiency can lead to NAFLD, there also also metabolic issues that can interfere with the bodies use of choline.
A deficiency in PEMT enzymes leads to fatty liver.
The vagus nerve can effect PEMT levels.
Misaligned vertebrae and vagus nerve.
Dysregulation of PEMT will result in liver dysfunction from choline deficiency. It is not mentioned in this study but nutrient deficiencies and metabolic issues like inhibited sulfation and issues with thiols can cause this. I have posted on those. Carcinogenic estrogen can build up in the body effecting these receptors. This can be caused by vaccine injury, heavy metals and glyphosate. Under normal health estrogen induces PEMT. PEMT homeostasis is important for preventing fibrosis throughout the body.
A deficiency in PEMT leads to fatty liver disease.
This is a more in depth article on PEMT.
PEMT issues can result in lung dysfunction.
High levels of certain gut bacteria , and high endotoxin levels can cause PEMT issues. I have posted on gut bacteria and how to reduce the strains mentioned, I think it was in my gut bacteria post. Leaky gut and infection causes high endotoxin levels and I have posted on how to address those.
SNAIL1 inhibition can reverse fatty liver caused by PEMT dysfunction.
A natural pesticide form the melia toosendan tree inhibits SNAIL1. It is used to get rid of parasites in the body.
Eucalyptol is a SNAIL1 inhibitor.
Insulin resistance caused by inflammation and oxidative stress can lead to NAFLD.
Betaine (TMG) helps with fatty liver.
Antitrypsins defiency can lead to NAFLD. Raw egg whites and Lima beans inhibit trypsin but I do not know if it will help , I could not find research on humans. Though there are studies on mice that show beans that have trypsin inhibitors in them being effective. There are studies showing the trypsin inhibitors in beans fight cancer.
Ursodeoxycholic acid reduces liver fibrosis. Inhibited sulfation can cause a deficiency in ursodeoxycholic acid. It can also cause sulfated ursodeoxycholic acid to build up in the liver causing damage. This can also cause problems in the intestines, resulting in inflammation and even intestinal lesions. There are a number of things that cause liver fibrosis and many of them can be addressed by increasing the gut bacteria that produce ursodeoxycholic acid.
I gut bacteria help keep our liver healthy.
Our gut bacteria also protect our livers from infection.
Parental nutrition effects the health of an infants liver.
Enterococcus Lactis protects the liver from oxidative stress.
Oligosaccharrides increase the beneficial bacteria that produce ursodeoxycholic acid, this helps with liver fibrosis which has been found to be common in those with SIBO.
Obeticholic acid reduces liver fibrosis.
Bile acid dysfunction has been connected to many chronic illnesses.
Metabolic issues effect bile acid production which can lead to illness.
Our gut bacteria regulate our bile acids, bile acid dysfunction can lead to kidney and liver disease.
Lithium in low doses heals the kidneys in high doses it can damage them.
Dybiosis can cause poor liver health regardless of our body fat levels.
Fasting increases HSP70 which helps with NAFLD. I have posted on HSP70
Ginseng may help with liver fibrosis.
Oligosacharride helps normalize our gut bacteria.
This study shows the importance of bile acid homeostasis in the prevention of NAFLD.
Nrf2 regulates bile acid homeostasis. I covered Nrf2 in my antioxidant post.
Trehalose reduces oxidative stress by regulating Nrf2/keap1 pathway and induces autophagy.
Choline metabolism and our gut bacteria are connected to liver disease. A sign of metabolic issues that need addressed is gall bladder trouble and indigestion when eating foods high in choline.
We need to get the correct fats an adequate amounts of cholesterol for bile production. We also must address issues that may cause a loss of cholesterol and fats by oxidation . I have posted on oxidative stress and inflammation.
I have posted on thiols. Cholesterol dysregulation can cause NAFLD.
Hemochromatosis can cause liver fibrosis. They claim it is genetic but I have seen studies showing toxins, infection and excess oxidative stress can cause it. Curcumine also reduces iron overload but taking it for too long can cause anemia. Lactoferrin reduces symptoms of iron overload by normalizing levels of iron in the blood though I have not research the safety of it’s use in liver disease.
This is a list of herbs that helps with hemochromatosis.
Liver fibrosis is caused by increased collagen production.
Porphyria can lead to fatty liver. I have posted on it.
Stringy Stonecrop help with liver fibrosis.
NAD+ may help with fatty liver.
Eleuthero reduces fatty liver.
Diosmetin found in citrus fruit reduces liver fibrosis.
Inhibiting USAG1 may help with Alport Syndrome. Proteinuria is part of the problem with Alport Syndrome. If I get a chance I will research the effects of protease on Alport Syndrome.
Biochanin A which is found in red clover and in the red papery covering of peanuts prevents liver fibrosis.
Relaxin helps reduce lung fibrosis which would help with COPD.
Bacteriodes Fragilis reduces liver injury.
I found this interesting IDO deficiency causes liver fibrosis. IDO deficiency can be caused by metabolic issues, toxins like mercury, glyphosate and glufosinate. Infection cause high quinolinic acid levels which can cause IDO deficiency. Also toxins from mold can cause IDO deficiency. High IDO levels can cause cancer so this is not something you would want to increase but something you would want to restore homeostasis to.
High MMP levels causes fatty liver.
This is a list of MMP inhibitors. I find it strange that many of these also fight viruses.
Fraxinux Excelsior seed helps reverse fatty liver.
Theraputic targets to help with fibrosis.
Those with liver fibrosis have been found to be deficient in Vitamin A.
Other vitamin deficiencies connected to liver fibrosis.
Zinc deficiency is common in cirrhosis of the liver.
Berberine helps with NAFLD.
Metabolic issues, oxidative stress, toxins especially mecury and glyphosate can cause the loss of retinoic acid receptor. I have posted on how to address those things.
Rumex Visicarius can help prevent liver disease.
Burdock root is hepaprtoective.
Kudzu has many healing properties. It is hepaprotective.
Though this is the kidneys I am sure this could happen in the liver also. Infection especially tick born illness can cause antiphospholipid syndrome. Vaccine injury can also cause this. Antiphospholipid syndrome can cause fibrosis in the kidneys.
Paeony helps reduce symptoms of kidney disease.
Low carbohydrate diet reduces kidney disease in diabetes. I have posted on diabetes. This would be a temporary fix. It is better to address the issues causing it.
List of herbs that help cleanse the kidneys.
Many medications can cause liver fibrosis especially fluoroquinolones.
Murcormycosis is a lung infection and if not addressed it can lead to liver disease and COPD.
Cristifolin found in Joe Pye helps with liver fibrosis but it contains an alkaloid that can build up in the body so I would not recommend over use.
How isoflavones protect the liver.
Sirt1 activators help reduce NAFLD.
Silymarin found in milk thistle seed inhibits mTOR which has been found to help with NAFLD.
Stevia Extract has hepaprotective properties.
Glyphosate causes liver damage resulting in liver fibrosis.
Cathepsin B causes NAFLD.
There are natural Cathepsin inhibitors but have not found studies on their effectiveness.
Japanese Honeysuckle helps with liver fibrosis.
Plantain herb is hepaprotective.
Artichoke is hepaprotective.
Yarrow protects the renal system and reduces oxidative stress.
yarrow protects the renal system.
reduces oxidative stress.
Ginger is hepaprotective and reduces oxidative stress.
Hibiscus is in the mallow family. Most plants in the mallow family are hepaprotective.
Hibiscus is hepaprotective.
Rose hip is hepaprotective.
White malberry helps with NAFLD
Sages have many healing abilities. Red Sage helps with liver fibrosis.
Red Sage helps reverse liver fibrosis.
Sirt activators help with NAFLD. Resveratrol found in grape seed extract is a sirtian activator.
Beta Glucan found in mushrooms, whey protein and whole grains help with liver fibrosis.
Beta glucan protects from fibrosis which is found in COPD and NAFLD.
Rooibos protects the renal system by reducing oxidative stress.
It also protects the renal system the same way.
Causes of lipid storage disease.
Oxidative stress causes renal damage, this is how Tylenol causes liver damage. Corn Silk helps protect the liver from oxidative stress, it is yummy to.
miR22 promotes liver fibrosis.
miR22 is modulated by our gut bacteria, our mRNA communicate with our gut microbiome. So if we have undressed health issues then this could be disrupted.
Plants that should be avoided because they have alkaloids that can destroy the liver or kidneys.
Plants with poison alkaloids.
Lipoxin reduces inflammation which should help with NAFLD. I have not had a chance to research how to increase lipoxin.
I do not like metformin because of the effects of long term use on the body. I am posting this to show that folic acid is toxic to the body and is used to damage the liver of animals in test. It is man made and our bodies make very little of the enzyme needed to break it down. This causes the excess that cannot be broken down to enter the blood stream causing damage throughout the body. Folate which is natrual does not have this effect on the body. They fortify our food with folic acid making it toxic, so those with NAFLD should try to avoid foods containing folic acid.
Glycogen storage disease.
Beta Glucuronidase is bad for NAFLD but helps with lysosomal storage disease.
Those with NAFLD can be deficient in B12
Mitochondrial disfunction is common in NAFLD, PQQ improves mitochondrial function.
Hibiscus is hepaprotective.
Red Sage helps reverse liver fibrosis.
Beta glucan protects from fibrosis which is found in COPD and NAFLD.
Reduces blood pressure.
Rooibos protects the heart by reducing oxidative stress and by reducing inflammation. Rooibos is also an ACE inhibitor.
Tenascan-C is needed for heart repair.
Tenascan-C is high in COPD
Tenascin-C is high in tissue injury which is why it is important to address the issues that are causing the injury. Whether it is metabolic issues, nutrient deficiencies, toxins , infection or oxidative stress. This also causes high oxLDL levels.
Fructose and NAFLD, fruit fructose is different it is processed fructose that causes the problem. Just as processed honey loses it’s health benefits so does processed fructose.
Insulin/Snail1 issues are involve in macrophagy which shows that NAFLD is a macrophagy issues.
Macrophagy issue also cause lipogenesis issues.
Those with NAFLD have glycolysis issues. This indicates macrophagy issues.
macrophagy issues have been linked to NAFLD.