Written by Lee Stevenson, sorry I am a lousy editor.
This is not medical advice I am writing this for educational purposes. If you are ill please seek the aid of a qualified and experienced medical practitioner.
Rhubarb root. (rheum Spp)
There are many varieties of rhubarb. The root is the part I will be focusing on because it contains emodin which is one of the few substances that will help with interstitial cystitis and Crohn’s disease. Rhubarb root also prevents herpes viruses from hijacking the mitochondria. It has very potent anti-inflammatory properties. It prevent fibrosis in the liver and lungs. Rhubarb root reduces inflammation in the gut. Rhubarb root has been found to balance the immune system. It helps normalize the gut microbial balance. It increases IgA which is low in interstitial cystitis and Crohn’s disease and many autoimmune disease. It helps restore proper T regulatory cell function. It has been shown to improve pancreatic function and health . Rhubarb root dramatically reduces the symptoms of sepsis. It should be pulsed because over use can increase risk of certain types of cancer and can be hepatoxic. This can occur with many nutrients so do not use in super high doses or excessively. I have seen people prescribed 50,000 IU of vitamin D. This causes kidneys stones and causes the vitamin D receptor to become inhibited which causes many health issues. Balance is the key to healing. More does not mean better. Rhubarb extract prevents osteoporosis. Rhubarb root improves kidney function. Rhubarb extract inhibits just about all the inflammatory cytokines found in sepsis , Sars-Covid infection and herpes infections. Rhubarb root improves kidney and liver function. Rhubarb root when used in moderation is safe to use long term. It has been shown to reduce the symptoms of menopause. Over all it looks like rhubarb root would be great at helping with and preventing autoimmunity.
Rhubbarb root (Rheum spp)
Rhubarb root has a broad rang of antibacterial properties.
I low doses it improves kidney function but in very high doses it can damage the kidneys. It has been shown to protect the body from many toxins. It reduces free radicals in the body which improves DNA function and prevents DNA damage.
Rhumbarb root improves glycolysis which would prevent accumulation of fat in the liver and would prevent obesity. It also improves liver function. When used in moderation it helps to prevent liver fibrosis.
It does stimulate the immune system so those whose immune system is already over active may want to be careful using rhubbarb root. It is unlikely it would cause a problem though because it does inhibit many receptors that are over-expressed in autoimmunity. It does increase TH2 expression so those who are TH2 dominant may want to use caution in using Rhubarb root.
It contains emodin which inhibits NLRP3. NLRP3 is over activated in interstitial cystitis and Crohn’s disease so it may help with those illnesses. Emodin also inhibits MAO B, this would help with Parkinson’s because it would prevent the body from breaking down dopamine. Inhibition of NLRP3 also prevents lung inflammation. Aloe vera also contains emodin.
Emodin in rhubarb root inhibits the Sars-Covid virus and also inhibits it’s ability to interact with the ACE2 receptor so may prevent Covid infection. Emodin has been found to be effective against many other types of viruses. Rhubarb root has also been found to inhibit many herpes viruses.
Emodin is also cardioprotective because it increases nitric oxide levels.
Rhubbarb root inhibits MCF-7 which can help with certain types of breast cancer.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601677/
Emodin found in rhubarb root has been found to decrease the inflammatory cytokines found in sepsis , inflammatory disease and autoimmune disease.
Emodin in rhubarb root inhibits intracellular influx of Calcium which prevents mast cell degranulation which would prevent high histamine levels. This can help with autoimmune diseases like asthma, lupus, psoriasis and many others. Also excess calcium in the cells can inhibit beta oxidation which can cause diabetes and obesity. Beta oxidation is how the body burns fat to create energy for the body. Emodin also increase browning of fat cells which prevents insulin resistance and obesity. Rhubarb root also increase the butyrate producing bacteria which helps to prevent obesity.
Emodin prevents the over activation of the NMDA receptor and other receptors in the brain. It is neuroprotective so can reduce the occurrence of seizures. It improves the function of the adrenals and many other areas of the brain. It prevents damage in the brain from excess glutamate. It also decreases the perception of pain so it would reduce pain in the body.
As stated earlier taking high doses of rhubarb root can have the opposite effects and actually damage the liver. It can also cause diarrhea, stomach cramping, It can also make the urine darker colored and even brown color.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116966/
https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/2047-9158-2-19
https://pubmed.ncbi.nlm.nih.gov/34306988/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137233/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6612377/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566906/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7730872/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167848/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168079/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143048/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997271/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912479/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754316/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601677/
https://pubmed.ncbi.nlm.nih.gov/32863857/
https://pubmed.ncbi.nlm.nih.gov/34159150/
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