Benefits of red sage.

Written by Lee Stevenson

This is not medical advice I am writing this for educational purposes. If you are ill place seek the aid of a qualified and experienced functional medicine practitioner.

Red Sage (Salvia miltiorrhiza)

In chinese medicine it is referred to as Danshen. Red sage improve cardiovascular health and has been shown to prevent strokes. Red sage has potent antioxidant properties. It also has potent anti-inflammatory properties. Because of red sage antioxidant and anti-inflammatory properties it helps to prevent fibrotic diseases like cirrhosis of the liver and Alzheimers disease. Though I have found no studies to support this statement I believe it would help with interstitial cystitis and inflammatory bowel diseases because it inhibits NLRP3 which is over expressed in those diseases. Red sage prevents diabetes induced eye injury and vision loss.

Red Sage improves brain function and cognition. It does thin the blood and prevents blood clotting. Most message boards that I have read on people who used it recommended only taking it for a month and then taking a one week break. Red Sage prevents high blood pressure by increasing nitric oxide levels. Nitric oxide is also one of the most potent antivirals used by the body. Because red sage improves blood flow and increases nitric oxide it prevents ischemia (tissue damage from inhibited blood flow).

Red Sage inhibits NADPH oxidase which is upregulate in inflammatory , and autoimmune diseases it inhibits beta oxidation and increases oxidative stress. Inhibiting NADPH oxidase would increase fat burning in the body and decrease oxidative stress. In order for that to occur mitochondrial respiration would have to increase so it would be safe to assume it improves mitochondrial respiration.

Nrf2 is the master regulator of the antioxidant system. Red sage is a potent Nrf2 activator which would increase antioxidant enzymes in the body.

Red sage increases mitophagy which is inhibited by RNA viruses like the herpes viruses. It also prevents autoimmunity by decreasing IgE levels which would prevent excess mast cell degranulation which would decrease histamines preventing and allergic response. It would also prevent over expreassion of TH2 immune response.

Red sage reduces oxalate levels in the body.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885196/

https://pubmed.ncbi.nlm.nih.gov/18361734/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478559/

https://pubmed.ncbi.nlm.nih.gov/29212498/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610889/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421141/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193940/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167655/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646978/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555792/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360890/

https://www.hindawi.com/journals/ecam/2019/1408979/

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