Alzheimers, Amyloidosis and amyloid plaque.

 

This is not medical advice I am posting this for informational and educational purposes.

If you have high amyloid levels in the body you may get lumps under your skin and the plaque can build up in organs and other tissues. Serrapeptase and a few other things will break up amyloid plaque.

I am posting what they believe about amyloid plaque. I believe amyloid plaque is a symptom and not the cause. I believe amyloid is used to protect the body from infection and toxins and if not addressed it will lead to amyloid build up. I also believe if others read the research they will most likely come to the same conclusion. Also if my theory is right natural helicase inhibitors , mugwort and other things that fight infection should also reduce amyloid plaque. I am going to look at the research and will post it in here if I am correct. I also believe amyloid is used when there is mitochondrial damage . It most likely will be found in cancer and I will post if I find that to be true in this information. If mitochondrial damage also causes amyloid plaque build up then I should be able to find research linking EMFs to amyloidoisis or Alhzheimers. Since all these things can be caused by gut dybiosis there should be a link there also. I have a theory I do not have time to prove but I think that amyloid could be found in many types of cancer because I believe the body is using amyloid plaques to try and isolate things from the body.

https://www.healthhype.com/what-is-amyloidosis-amyloid-deposits-disease-types-pictures.html

https://www.naturalhealth365.com/amyloid-plaque-dementia-2138.html

http://alzheimerborreliosis.net/wp-content/uploads/2012/10/PlaquesAlz.pdf

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086039/

If not addressed amyloidosis can result in chronic illness and organ failure.

https://www.ajronline.org/doi/full/10.2214/AJR.14.13864

https://www.clinicalradiologyonline.net/article/S0009-9260(89)80201-6/pdf

http://err.ersjournals.com/content/26/145/170046

https://www.tandfonline.com/doi/abs/10.3109/13506129.2014.943834

It can even form structures in the body that will remind you of something out of and alien movie.

https://jamanetwork.com/journals/jamadermatology/fullarticle/2091532

My question is why are amyloid plaque formations usually round and cyst formed by a pathogen contain amyloid and are usually round.

https://www.ncbi.nlm.nih.gov/pubmed/23082034

https://www.ncbi.nlm.nih.gov/pubmed/21816039

https://www.frontiersin.org/articles/10.3389/fnagi.2018.00048/full

https://www.sciencedirect.com/science/article/pii/S0005273614002818

Amyloid has been linked to alzheimers and chronic illness. Infection, toxins like aluminum found in vaccines. Mercury still used in some vaccines can cause high amyloid levels. Also some farm chemicals found in our foods can cause it. Excess EMF exposure has been linked to amyloid plaque formation in the body. Amyloidosis is when amyloid plaques form throughout the body and can be caused by the same things. Infections especially Lyme disease can result in B-amyloid formations. Also keep in mind that the amyloid plaques do not only build up in the brain but in others areas of the body and can result in amyloidosis instead of Alzheimer’s. In my opinion amyloidosis and Alzheimers run hand and foot because they share so many commonalities. So what helps one should help the other. I could list hundreds of studies showing vaccines cause Alzheimer’s even those that do not contain aluminum and mercury. As I looked at the research the things that help Alzheimer’s also helps with amyloidosis and Non Alcohol Fatty Liver disease. I would not doubt if it helped with COPD also. I am starting to think high amyloid levels can be linked to many chronic diseases. I will most likely be updating this because seeing the links of amyloid in other chronic diseases make me curious of what other illnesses it can be linked to like diabetes, hormonal issues, thrombosis etc.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204502/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137286/

Ironic that doxycycline fights Lyme and amyloidosis.

https://www.ncbi.nlm.nih.gov/pubmed/23734692

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428475/

https://www.ncbi.nlm.nih.gov/pubmed/25577494

https://www.academia.edu/6207102/b-Amyloid-aluminum_complex_alters_cytoskeletal_stability_and_increases_ROS_production_in_cortical_neurons

https://www.scirp.org/journal/PaperInformation.aspx?PaperID=53106

http://info.cmsri.org/aluminum-and-your-health-blog/aluminum-should-now-be-considered-a-primary-etiological-factor-in-alzheimers-disease?utm_campaign=Aluminum&utm_content=55912812&utm_medium=social&utm_source=facebook

https://www.journals.elsevier.com/journal-of-trace-elements-in-medicine-and-biology

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651029/

https://www.ncbi.nlm.nih.gov/pubmed/11130287

https://www.ncbi.nlm.nih.gov/pubmed/26897372

https://link.springer.com/article/10.1007%2Fs007020050038

https://jameslyonsweiler.com/2017/11/23/biological-mechanisms-of-vaccine-injury/

Oxidative stress induced.

https://www.researchgate.net/publication/247660057_Mercury_Induces_Cell_Cytotoxicity_and_Oxidative_Stress_and_Increases_-Amyloid_Secretion_and_Tau_Phosphorylation_in_SHSY5Y_Neuroblastoma_Cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680523/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749710/

Since iron is an oxidizer it stands to reason that it would be link to amyloid plaque deposites. Since curcumin chelates iron it recudes amyloid plaque, it also reduces BACE1

http://www.jbc.org/content/286/6/4248.long

https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-14-88

Usually I recommend lactoferrin to those who are healing but seems it should not be recommended to those with high amyloid levels.

https://www.alzheimersanddementia.com/article/S1552-5260(17)30469-7/abstract

Vaccinations can cause amyloidosis.

https://www.researchgate.net/publication/236187341_AA_Amyloidosis_in_Vaccinated_Growing_Chickens

https://www.sciencedirect.com/science/article/pii/S0005273607000387?via%3Dihub

Nrf2/keap1

https://www.fiercebiotech.com/research/activating-a-cell-protecting-protein-could-ward-off-alzheimer-s-symptoms

https://www.frontiersin.org/articles/10.3389/fncel.2018.00126/full

Many things can cause autoimmune disorders and they have been linked to brain damage. Which can lead to amyloidosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086677/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961620/

http://amyloidosis.org/facts/aa/

Amyloidosis.

https://my.clevelandclinic.org/health/diseases/15718-amyloidosis

https://www.cancer.net/cancer-types/amyloidosis/symptoms-and-signs

https://www.ncbi.nlm.nih.gov/pubmed/24278249

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1942261/

Drugs can induce amyloidosis.

https://www.ncbi.nlm.nih.gov/pubmed/1376976

Ethylene Glycol is found in vaccinations. This is antifreeze.

https://www.ncbi.nlm.nih.gov/pubmed/26721368

Glyphosate has been found to effect the human brain also. It can even alter a persons sexual preference.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550406/

https://www.theunion.com/news/twi/glyphosate-roundup-and-its-link-to-celiac-disease-gluten-intolerance/

https://detoxproject.org/glyphosate/glyphosate-and-roundup-negatively-affect-gut-bacteria/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040025/

There are many toxins we are subjected to that damage the brain.

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70278-3/abstract

Oxidative stress.

https://www.frontiersin.org/articles/10.3389/fphar.2016.00061/full

https://academic.oup.com/biomedgerontology/advance-article-abstract/doi/10.1093/gerona/glx177/4371617?redirectedFrom=fulltext

https://www.ncbi.nlm.nih.gov/pubmed/10931172

https://www.sciencedirect.com/science/article/pii/S1011134417307030?via%3Dihub

Even sleep deprivation can contribute to the build up of amyloid.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924922/

https://www.ncbi.nlm.nih.gov/pubmed/24199995

Food sources that can cause amyloid plaque build up.

https://www.sciencedirect.com/science/article/pii/S0925443914000064

Infection as a source of amyloidogenic proteins.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794723/

http://www.miklossy.ch/

https://www.sciencedirect.com/science/article/pii/S0197458013003308?via%3Dihub

https://www.ejradiology.com/article/S0720-048X(09)00298-8/fulltext

Amyloid works as an antibiotic in the body so is a sign of infection.

https://www.sciencedaily.com/releases/2016/05/160525161351.htm

Proton Pump Inhibitors cause B-amyloid to build up.

https://jamanetwork.com/journals/jamaneurology/fullarticle/2487379?utm_source=facebook&utm_medium=social_jamaneur&utm_campaign=article_alert&utm_content=automated

Some food additives contribute to amyloid build up.

https://www.dementia.org/study-links-diacetyl-to-alzheimers-disease

https://bebrainfit.com/neurotoxins-foods/

http://www.holistichelp.net/toxins.html

Lyme uses calcium to form cyst to protect itself. The body tries to farther isolate it from the body by building up a layer of amyloid on it. This can severely effect the health of our body and can result in amyloidosis. There are other infectious diseases that can cause this to occur. I remember I was looking at an image of Alzheimer’s and the amyloid plaque on the brain. As I was looking at it a friend sent a picture of the Lyme cyst on her brain. I was shocked they looked identical. Could Alzheimer’s be an infection?

https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-5-40

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753746/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129439/

https://www.ncbi.nlm.nih.gov/pubmed/30001512

https://www.ncbi.nlm.nih.gov/pubmed/29980196

It stands to reason that diabetes would be linked to Alzheimer’s. Diabetes can be caused by oxidative stress, inflammation, and even autoimmune disorders. All these things can cause amyloid plaque to build up.

https://www.practicaldiabetes.com/article/type-3-diabetes-brain-insulin-resistant-state-linked-alzheimers-disease/

http://www.greenmedinfo.com/blog/sugar-and-your-brain-alzheimer’s-disease-actually-type-3-diabetes

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925815/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434080/

Toxins in our food like BT Toxin , glufosinate, and glyphosate can cause a leaky blood brain barrier. Many drugs can also cause this especially fluoroquinolones. Leaky gut and gut dysbiosis can also lead to a leaky blood brain barrier. The can cause amyloid plaque to build up. So can metabolic issues that lead to acidosis or alkaloidosis.

https://www.frontiersin.org/articles/10.3389/fnagi.2014.00171/full

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687937/

https://www.nature.com/articles/nature22075

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879184/

https://floxiehope.com/2015/06/13/hacking-fluoroquinolone-toxicity-via-the-nervous-system/

https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.200700075

https://www.ncbi.nlm.nih.gov/pubmed/24604078

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102282/

Our gut bacteria protect us from toxins.

https://www.researchgate.net/publication/312447778_Lactobacillus_plantarum_CCFM639_can_prevent_aluminium-induced_neural_injuries_and_abnormal_behaviour_in_mice

The glymphatic system is involved in keeping the brain cleaned out. I am not certain but I think I covered this in my detox post. When it becomes blocked it negatively effects the brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681909/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636982/

https://www.ncbi.nlm.nih.gov/pubmed/25521178

Bad body posture can result in poor glymphatic system function. Chiropractors were ahead of their time on this one.

http://www.jneurosci.org/content/35/31/11034

Fluoride found in most public drinking water damages the brain.

https://www.researchgate.net/publication/291795479_Effects_of_endemic_fluoride_poisoning_on_the_intellectual_development_of_children_in_Baotou

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997496/

https://www.ncbi.nlm.nih.gov/pubmed/25556215

Vaccine injury , toxins, mold and infections can cause high quinolinic acid which can cause inflammation the the brain. They can cause B6 to become depleted which raises quinolinic acid levels.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1217971/

Tick born illness especially Lyme can lead to high quinolinic acid levels.

http://n.neurology.org/content/42/1/43.short

Heavy metals like mercury and aluminum damage the brain. Metallothionein helps remove heavy metals from the body thus protecting the brain. It also helps protect from free radicals and oxidative stress.

https://www.hindawi.com/journals/omcl/2017/5828056/abs/

https://metabolichealing.com/metallothionein-forgotten-antioxidant-missing-puzzle-piece-for-alzheimers-leaky-gut/

Chromium increases metallothionein but we must be careful because chromium can increase insulin levels and we do not want to increase them too much. Zinc is also needed for metallothionein, I get my from unfiltered raw honey. What confuses me is they consider zinc an inert molecule that is not part of the redox system but it is heavily involved in redox.

https://www.researchgate.net/publication/12629060_Chromium_increases_pancreatic_metallothionein_in_the_rat

https://academic.oup.com/jn/article/130/5/1455S/4686413

There are many nutrients that can increase metallothionein.

https://biofoundations.org/inducing-metallothionein-for-heavy-metal-detoxification-and-reducing-oxidative-stress/

They claim it can be genetic but many things they claim are genetic often times are not genetic but can be linked to habits passed down to us from family, our microbiome or environmental factors. So even though they claim it is genetic I believe change the environment internally and externally and you can change the condition.

https://www.ajmc.com/journals/supplement/2017/hereditary-attr-amyloidosis-burden-of-illness-and-diagnostic-challenges/hereditary-attr-amyloidosis-burden-of-illness-and-diagnostic-challenges-article?p=2

Since amyloid is part of the immune system and cancer can be caused by immune dysfunction it stands to reason that amyloid would be tied to cancer. Have a blog post on cancer that could compliment this information.

http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=7103&path%5B%5D=20217

http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=2990&pubmed-linkout=1

https://www.sciencedirect.com/science/article/pii/S0006291X1202390X?via%3Dihub

If amyloidosis is not addressed it can lead to cutaneous amyloidosis.

https://www.dermcoll.edu.au/atoz/cutaneous-amyloidosis/

https://www.dermnetnz.org/topics/amyloidosis/

http://www.pcds.org.uk/clinical-guidance/amyloidosis-cutaneous

Yep stands to reason EMFs can cause mitochondrial damage so increasing amyloid in the brain is bound to occur. Frequency does matter. There are studies showing certain frequencies actually reduce amyloid.

https://www.arcmedres.com/article/S0188-4409(13)00076-3/fulltext

https://www.sciencedirect.com/science/article/pii/S0188440913000763

https://www.ncbi.nlm.nih.gov/pubmed/7677130

http://www.vagbrytaren.org/Hur_tradlos_teknik_skadar_20160310%20(1).pdf

https://www.lnl.infn.it/~annrep/read_ar/2007/contributions/pdfs/063_B_80_B075.pdf

http://www.mdpi.com/1660-4601/15/1/17/pdf

This is the frequency of many cordless phones.

https://www.tandfonline.com/doi/abs/10.3109/15368378.2011.624654

https://www.ias.ac.in/article/fulltext/jbsc/043/02/0263-0276

Leaky gut can permit more LPS to enter the blood stream resulting in high amyloid protein levels. Glyphosate, glufosinate and BT Toxins in GMOs can cause leaky gut. So can heavy metals like mecury and lead. Many antibiotics especially fluorquinolones can cause leaky gut so even if they reduces symptoms of Alzheimers they would cause changes that increase chance of getting Alzheimer’s.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469284/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428612/

https://academic.oup.com/nutritionreviews/article/74/10/624/2349955

http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006654

BACE1 involvement in amyloid plaque.

https://www.ncbi.nlm.nih.gov/pubmed/15126696

Inhibiting BACE1 reverses Alzheimer’s.

http://jem.rupress.org/content/early/2018/02/13/jem.20171831

Alpinia Officinarum has galagin which reduces BACE1.

https://www.researchgate.net/publication/299485461_The_Natural_Product_Galangin_is_an_APP-Selective_BACE_Inhibitor_and_a_Potential_Alzheimer’s_Disease_Therapeutic

Pastacia integerrima known as zebra wood contains a BACE1 inhibitor.

https://www.tandfonline.com/doi/abs/10.1080/14786419.2014.997231?journalCode=gnpl20

Genistein may inhibit BACE1.

https://www.liebertpub.com/doi/abs/10.1089/jmf.2017.4068

Other compounds that may inhibit BACE4

http://www.scholarsresearchlibrary.com/articles/targeting-bace-1beta-secretase-through-polyphenolic-compounds-a-computational-insilico-approach-with-emphasis-on-binding.pdf

Things that may help.

Detoxing aluminum.

https://realfarmacy.com/mineral-waters-remove-aluminum-from-brain/

Nattokinase and Serrapeptase help reduce amyloid and in some studies has been shown to reduce amyloid plaque. These should be used in moderation, very high doses can cause damage in the body.

http://journals.sagepub.com/doi/abs/10.1177/0960327112467040?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

Black Sativa helps protect the brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789020/

There are a number of intervention methods that may help with Alzheimer’s.

https://www.hindawi.com/journals/bmri/2016/2589276/abs/

Reducing inflammation helps with Alzheimer’s.

https://journals.lww.com/co-neurology/Abstract/2005/06000/Role_of_inflammation_in_neurodegenerative_diseases.19.aspx

Probiotics can help with alzheimers.

https://www.healyounaturally.com/9-things-you-never-knew-probiotics-could-do-to-improve-your-health/

Cognitive reserve can help protect from Alzheimer’s.

https://www.verywellhealth.com/what-is-cognitive-reserve-98397

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507991/

Astaxanthin found in krill oil reduces oxidative stress. I have posted on oxidative stress.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746928/

High cholesterol improves memory function.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614555/

Statins damage the brain by depriving it of cholesterol.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253844/

https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-016-0877-8

https://www.westonaprice.org/health-topics/modern-diseases/dangers-of-statin-drugs-what-you-havent-been-told-about-popular-cholesterol-lowering-medicines/

Low cholesterol can harm your health.

http://www.greenmedinfo.com/blog/underreported-dangers-low-cholesterol

Cholesterol dysregulation contributes to Alzheimer’s. This has also been found to contribut to NAFLD.

https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/1750-1326-5-36

https://www.researchgate.net/publication/264633405_Expression_of_Liver_X_Receptor_Correlates_with_Intrahepatic_Inflammation_and_Fibrosis_in_Patients_with_Nonalcoholic_Fatty_Liver_Disease

https://academic.oup.com/edrv/article/33/5/715/2354830

This is usually caused by oxidative stress or an autoimmune disorder.

http://www.funpecrp.com.br/gmr/year2013/vol12-4/pdf/gmr2612.pdf

https://www.researchgate.net/publication/311781576_Cholesterol_Accumulation_in_CD11c_Immune_Cells_Is_a_Causal_and_Targetable_Factor_in_Autoimmune_Disease

https://www.jci.org/articles/view/74141

Cholesterol regulation in the body.

https://onlinelibrary.wiley.com/doi/full/10.1111/j.1755-5922.2008.00062.x

Cholesterol decreases inflammtion but high insulin levels can interfere with that.

https://www.sciencedirect.com/science/article/pii/S0959437X08000968

https://www.ncbi.nlm.nih.gov/pubmed/26511317

Desmosterol and other natural phytosterols are LXR agonist and help with cholesterol dysregulation.

http://www.pnas.org/content/115/20/E4680

Silica may help with Alzheimer’s.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546016/

All the above mentioned things can cause brain fog. Luteolin helps reduce brain fog.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490655/

Tryptophan improves brain function.

https://plenteousveg.com/tryptophan-foods/

Citric acid and citrate found in the white part of citrus fruits help protect the brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026104/

Ebselem a drug for mental illness has been found to reduce oxidative stress and protect the brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759215/

Flax seed oil reduces oxidative stress.

http://journals.sagepub.com/doi/abs/10.1177/0960327115571765

Phosphatidylserine has been shown to help with cognitive decline.

https://bebrainfit.com/phosphatidylserine-benefits/

Balancing GABA and Glutamate help improve cognitive function.

http://www.holistichelp.net/blog/how-to-increase-gaba-and-balance-glutamate/

B6 reduces brain inflammation and quinolinic acid. High quinolinic acide levels can lead to alzheimers.

http://www.hormonesmatter.com/reducing-brain-inflammation-vitamin-b6/

Increasing melatonin helps reduce the toxicity of quinolinic acid.

https://www.sciencedirect.com/science/article/pii/S0028390899001288

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1571800/

I prefer natural sources of melatonin if they it is low there are natural sources and natural ways to increase it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3304366/

Sulforapane helps reduce quinolinic acid so it is important to get things that inhibit sulfation like glyphosate and mercury reduced in the body and address things that cause high hydrogen sulfite levels like gut dysbiosis addressed. If not then high sulfur foods will make a person sicker.

https://www.researchgate.net/publication/262569040_Sulforaphane_reduces_the_alterations_induced_by_quinolinic_acid_Modulation_of_glutathione_levels

Selenium reduces quinolinic acid. A good source of selenium is brazil nuts.

https://www.ncbi.nlm.nih.gov/pubmed/12871589

L-theanine reduces quinolinic acid.

http://www.mdsabstracts.org/abstract/neuroprotective-potential-of-l-theanine-against-excitotoxic-neuronal-death-induced-by-quinolinic-acid-possible-neurotransmitters-and-nitric-oxide-modulation-mechanism/

Curcumine reduces quinolinic acid and is absorbed better when taken with black pepper. If curcumine is taken for too long it can make a person anemic. It can chelate iron from the body.

https://www.karger.com/Article/PDF/443896

Inositol Hexaniacinate is a special form of niacin that prevents the uncomfortable flushing that can come from taking nicacin. Niacin can reduce guinolinic acid by reducing tryptophan shunting to the quinolinic pathway. It has also been found to reduce oxLDL levels.

http://www.anaturalhealingcenter.com/documents/Thorne/articles/InositolHexaniacinate.pdf

https://lpi.oregonstate.edu/mic/vitamins/niacin

http://www.functionalps.com/blog/2012/12/01/tryptophan-metabolism-effects-of-progesterone-estrogen-and-pufa/

There are many plant extracts that effect the brain in a variety of ways.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597072/

Insulin-like Growth Factor protects the brain, helps build muscle. Now the bad high levels can feed cancer. It reduces insulin tolerance, and can be linked to cardiovascular disease. In my opinion this should only be increased if you are healing because it is a hormone needed when we are young and still growing. Vitamin D, Fish, milk and chicken increase IGF-1. Getting enough sleep and exercise increases IGF-1

http://www.life-enhancement.com/magazine/article/2735-natural-products-to-clear-amyloid-beta-from-the-brain

https://www.medicalnewstoday.com/articles/255957.php

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183292/

https://www.health24.com/Diet-and-nutrition/Nutrition-basics/What-we-know-about-IGF-1-20120721

https://www.medpagetoday.com/endocrinology/generalendocrinology/40932

https://www.nutronicslabs.com/blogs/posts/how-to-naturally-increase-your-igf-1-levels

Inhibiting acetycholesterinesterase helps with alzheimers.

https://www.ncbi.nlm.nih.gov/pubmed/29513045

Linarin inhibits acetylcholesterinesterase.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518125/

Japanese honeysuckle protects the brain by reducing inflammation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492671/

Manganese deficiency can lead to chronic illness it is need in many metabolic pathways but should be used in moderation because if taken in excess it can damage the brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886254/

Gingko helped me a lot but I have seen studies that have shown long term use can cause liver damage. I had a strange reaction at first it gave me a bad headache but after a day or two of taking it I noticed I could think clearer.

https://www.jstage.jst.go.jp/article/bpb/37/2/37_b13-00378/_article

Wild Violet protects from oxidative stress.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967839/

Their are many nootropic herbs they improve cognitive function.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459457/

NAC reduces oxidative stress. NAC is one of those supplements that should be pulsed because I noticed that if you take it too often it can start having negative effects on the health.

https://link.springer.com/article/10.1007/s00134-007-0880-z

High glutamate levels can damage the brain. There are many environmental factors now days that can cause high glutamate levels.

http://dana.org/Cerebrum/Default.aspx?id=39382

Passion Flower protects from glutamate toxicity but I have seen studies that show long term use can start damaging the liver.

https://www.ncbi.nlm.nih.gov/pubmed/27693740

There are natural ways to reduce glutamate.

http://rlcure.com/glutamate2.html

Self heal helps improve concentration.

https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.4929?

Rhodiola helps protect the brain.

https://mentalhealthdaily.com/2015/07/20/rhodiola-rosea-benefits-scientific-research/

Silence promotes brain healing.

https://www.lifehack.org/377243/science-says-silence-much-more-important-our-brains-than-thought

Serrapeptase and Nattokinase help with Alzheimer’s , it stands to reason because they break down amyloid plaque.

http://journals.sagepub.com/doi/abs/10.1177/0960327112467040?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

Saffron helps with memory loss.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599112/

PQQ helps repair the brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303106/

Increasing myelin to improve brain function.

https://www.selfhacked.com/blog/myelin/

Cannabinoids help break down amyloid plaque.

https://www.sciencedaily.com/releases/2016/06/160629095609.htm

Naturals that help reduce amyloid plaque.

http://www.raysahelian.com/amyloid.html

Coconut Oil reduces amyloid plaque.

http://naturalsociety.com/new-study-coconut-oil-helps-remove-amyloid-plaques-brains-alzheimers-patients/

Antioxidants that help with amyloid.

https://www.researchgate.net/publication/276152979_Medicinal_plants_and_their_derivatives_with_amyloid_beta_inhibitory_activity_as_potential_targets_for_drug_discovery

https://biofoundations.org/natural-compounds-that-promote-anti-aggregation-and-clearance-of-amyloid-beta/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805747/

Looks like more then a theory.

Mugwort kills many types of pathogens and it reduces amyloid.

https://www.sciencedirect.com/science/article/pii/S1995764517310040

Antioxidants reduce amyloid.

https://www.sciencedirect.com/science/article/pii/S1021949817300534

https://sarooibos.co.za/rooibois-could-reduce-risk-of-type-3-diabetes-a-precursor-to-alzheimers-disease/

Though I do not like the antibiotic used in this study because fluoroquinolones do more harm then good this show antibiotics help.

https://neurosciencenews.com/ceftriaxone-antibiotic-alzheimers-5518/

Other antibiotics work also.

https://academic.oup.com/brain/article/139/5/1568/2468752

https://www.omicsonline.org/open-access/repurposing-clinically-used-antibiotics-for-the-treatment-ofalzheimers-disease.pdf

Mullein has antibiotic properties and reduces amyloid.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774200/

Olive leaf kills pathogens even HIV, it reduces amyloid.

https://www.sciencedirect.com/science/article/pii/S1044030508002237

Gotu Kola kills many pathogens and it reduces amyloid.

https://content.iospress.com/articles/journal-of-alzheimers-disease/jad00806

Cinnamon kills pathogens and you guessed it.

https://www.scholars.northwestern.edu/en/publications/orally-administrated-cinnamon-extract-reduces-β-amyloid-oligomeri

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Synergistic Illness.

This is not medical advice I am posting this for educational and informational purposes.

Mitochondria regulate our immune response and oxidative stress. Many things can cause mitochondria dysfunction. This can lead to metabolic issues, excess oxidative stress and autoimmunity which can lead to cancer and other chronic illness.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052888/

As you read this you will come to realize why so many are getting Lyme disease and many other illnesses. Our bodies are under assault by fake science also known as corporate science. The science it is based on has been proven wrong yet they push it as fake. Because of that many have developed chronic illness.  Learning how the immune system really works is the first steps to healing.

There are many things that effect our immune system. The amount of toxins in the body, oxidative stress, infections, vaccine injury, processed foods, GMOs and farm chemicals. How we address immune related issues depends on what caused them and the what health problems we have. For example many things cause inflammation which has a dramatic effect on the immune system. Some things will cause mast cell activation which can cause the body to turn on itself. Most illnesses you will find are an autoimmune issue. Inflammation and oxidative stress are the main contributors to autoimmunity. Immunity does not work like pharmaceutical science states it does. They are either lying or doing some of the worst scientific research in the history of man. If you read how the vaccine producers claim vaccines give immunity you will see the very things they claim help the vaccine give immunity are found to be common in autoimmune disorders. They in some way have come to believe stimulating the very things that cause dysfunction in the immune system would impart immunity. How would disabling the immune system impart immunity? I cannot bring myself to believe they are not aware of those facts. If you read the information believe you will see why vaccine will never work. Our immune system works nothing like the fake corporate science leads people to believe it does.

This is just a partial list of the things that are causing modern day illness. There are many other things like heavy metal, and other toxins. If I get time I will update this.

Oxidative stress contributes to chronic illness and cancer. You will hear it mentioned often. There is a test for oxidative stress. It is the Urinary 8-OHdG test.

https://www.sciencedirect.com/science/article/pii/S0009898103004534?via%3Dihub

There are other test that can help identify which areas of the anti-oxidant system are working and which may not be working. This can help identify the sources of high ROS levels or other toxins produced in the body from oxidative stress.

https://drjockers.com/oxidative-stress-test/

They are incorrect about so many things for example they claim genetics cause disease but that is being proven wrong more and more.

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0154387

They claim antibodies prove immunity but antibodies aren’t even required for immunity.

https://www.sciencedaily.com/releases/2012/03/120301143426.htm

A break down of our environment effects our health.

https://www.frontiersin.org/articles/10.3389/fimmu.2017.01501/full

Autophagy is required to develop immunity but I truly believe it should be to develop a symbiont relationship.

https://www.ncbi.nlm.nih.gov/pubmed/29654322

Now inflammation and autophagy work together but the toxins in vaccines cause inflammation. So this would mean it would cause a dis-regulation of autophagy.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933864/

Vaccine producers themselves say they need to cause inflammation for the vaccine to be effective. They are effective at producing autoimmunity because of their fake science.

https://www.ncbi.nlm.nih.gov/pubmed/28741088

Now when you read the research it becomes clear allergies and asthma are caused by inflammation. Instead of looking for the cause they try treating the symptoms. My question is why do they not look for the cause? Do they already know it is vaccine injury so dance around it to prevent being exposed? Vaccinations are known to make people more susceptible to getting allergies and asthma. Also sugar causes inflammation which will make us more susceptible to allergies and asthma. Many toxins in our food now days cause inflammation and the ingredients in our foods are based on the honor system. The government expects the manufacturers to self regulate what they put in foods for the most part.

https://blog.healthmatters.io/2018/07/27/what-is-gamma-globulin-function-interpretation/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800381/

Instead of looking for the cause they try treating the symptoms. It is a common theme now days. They dance around the cause of any illness because they know what it is. They also know they will expose powerful people if they try addressing the cause so they go into cover up mode. Treat the symptoms instead of the cause so they do not expose those responsible for the cause.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698748/

https://www.achooallergy.com/learning/chronic-inflammation-chronic-disease/

For example a high salt diet can cause an imbalance in gut bacteria which leads to hypertension. Eating habits are passed down from our parents. Even how we interact with others is not genetic, but is determined by the health of our gut microbiome.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865374/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960464/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006525/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928587/

https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-018-0525-6

Many are coming to realize our gut microbiome modulate our genes and that many things are not cause be inherited genetics.

https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-018-0466-8#main-content

The whole theory behind vaccinations is severely flawed. They are so flawed that vaccinations have caused diseases to develop that are worse then the ones they are supposedly protecting people from.

They have discovered that adaptive immunity is not how our bodies protect themselves.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359130/

http://www.greenmedinfo.com/blog/herd-immunity-flawed-science-and-mass-vaccination-failures

Studies like this frustrate me. Cholesterol is an antioxidant, when there is high oxLDL it indicates that there is either a high toxin level, or an infection. These studies seem to over look that even though they know that cholesterol is an antioxidant and an anti-inflammatory. It means the cholesterol is doing it’s job. They are looking at a symptoms instead of looking for the cause. Even lowering inflammation will not get rid of the oxLDL they have to address the cause. It is not the cholesterol making the T cell levels go up but it is the oxLDL because that is telling the body something is wrong.

https://www.nature.com/articles/s41598-017-15546-8

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723280/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543092/

Some aspects of autoimmunity.

https://www.immunophen.com/blogs/news/explaining-immune-dysfunction-syndromes

Function of the spleen.

https://www.thoughtco.com/spleen-anatomy-373248

Vitamin A deficiency can effect the immune system.

https://www.ebi.ac.uk/interpro/potm/2005_6/Page2.htm

Regulatory T cell keep our immune system at homeostasis. A deficiency can cause allergies and other autoimmune issues. It is very common for those with inflammatory bowel disorders to have low T reg levels.

https://academic.oup.com/intimm/article/21/10/1105/883857

https://clinicalmolecularallergy.biomedcentral.com/articles/10.1186/1476-7961-7-5

Bad gut health can cause T cell issues.

https://blog.bulletproof.com/how-to-own-your-gut-bacteria-and-fix-leaky-gut-syndrome/

http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0106335

https://aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/hep.25704

Our Microbiome and our immune system

Our microbiome regulate lung health.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710201/

https://www.ncbi.nlm.nih.gov/pubmed/28295020

https://www.ncbi.nlm.nih.gov/pubmed/29142211

Clostridium Leptum blances the immune system

https://www.sciencedirect.com/science/article/abs/pii/S0198885914004571

Lactobacillus Crispatus doesn’t only prevent obesity it prevents candidia infection.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308008/

Our microbiome regulate our immune system.

http://www.pnas.org/content/108/13/5354

https://www.hindawi.com/journals/bmri/2018/4178607/

https://www.sciencedirect.com/science/article/pii/S1074761312002373

https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0921-4

We also have commensal fungus that help modulate immunity.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332855/

Our gut microbiom protects us from allergies.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026470/

https://immunenetwork.org/DOIx.php?id=10.4110/in.2018.18.e15

http://www.mdpi.com/2072-6643/9/7/672

https://asthmarp.biomedcentral.com/articles/10.1186/s40733-017-0037-y

http://www.jimmunol.org/content/198/7/2689.long

https://www.cell.com/cell/fulltext/S0092-8674(16)31403-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867416314039%3Fshowall%3Dtrue

Our gut bacteria protect us by increasing T regulatory cells which keeps our immune system at homeostasis.

http://science.sciencemag.org/content/351/6275/858

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276397/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574601/

This is why antibiotics make us more prone to developing allergies.

https://aacijournal.biomedcentral.com/articles/10.1186/s13223-016-0148-7

Identifying and dealing with milk allergies.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537845/

The earlier a child is intoduced to beneficial gut microbiome the better the chances of them getting established are.

https://www.frontiersin.org/articles/10.3389/fped.2017.00111/full

https://www.frontiersin.org/articles/10.3389/fmicb.2018.01376/full

https://www.nature.com/articles/ismej2015151

It can even influence a childs mental health later in life. Mental illness is autoimmune disease.

https://link.springer.com/article/10.1007%2Fs13311-018-0604-9

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1571800/

Many artificial sweeteners cause weight gain and inflammation because of their negative impact on our gut microbiome.

https://www.ncbi.nlm.nih.gov/pubmed/28594855

Our gut bacteria train our immune system.

https://onlinelibrary.wiley.com/doi/abs/10.1111/imm.12896

Our gut bacteria are part of the redox system which is our antioxidant system.

https://elifesciences.org/articles/35987

Our gut bacteria have effects on the health of our whole body.

https://link.springer.com/article/10.1007%2Fs13238-018-0547-2

https://www.hindawi.com/journals/bmri/2018/9478630/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788971/

Vaccinations, GMOs and farm chemicals especially glyphosate raise zonulin levels. This makes us sensitive to glutin, gliaden and lactose. Our gut bacteria regulate our tight junction protein layer to protect us from toxins and from food particles entering out blood stream. Once they enter out blood stream our bodies will start producing antibodies against them.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156689/

How our diet effects our immune system. Our diet effects our microbiome.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276397/

https://onlinelibrary.wiley.com/doi/abs/10.1177/0148607104028005348

https://www.ncbi.nlm.nih.gov/pubmed/24129165

Since our gut bacteria regulate our immune system things that disrupt them like farm chemicals in our food , antibiotics, GMOs, or even mercury and other heavy metals can cause us to develop autoimmunity. Many do not realize mental illness, heart disease, diabetes, COPD, liver and kidney disease is often times cause by an autoimmune disorder.

https://www.ncbi.nlm.nih.gov/pubmed/28197336

Our gut bacteria modulate our brain health.

https://aacijournal.biomedcentral.com/articles/10.1186/s13223-016-0148-7

http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0106335

We need to take a probiotic that has the prebiotic specific to the bacteria we are lacking in order for it to establish itself in the gut when taking probiotics to prevent allergies.

https://www.nature.com/articles/pr2017270

antibiotics cause inflammation by their effects on our gut microbiotia.

https://gut.bmj.com/content/65/7/1100.long

Allopathic medicine can contribute to candida causing autoimmunity.

https://ccforum.biomedcentral.com/articles/10.1186/s13054-016-1182-z

Many with MS have been shown to have high levels of methane producing bacteria.

https://www.nature.com/articles/ncomms12015

Some infections prevent allergies.

https://m.jci.org/articles/view/45041

Microbiota in our bodies are what protects us not adaptive immunity.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359130/

They call candida a pathogen yet it is part of the human gut microbiome. Showing that when things go wrong then so do our commensal bacteria.

https://academic.oup.com/femsyr/article/15/7/fov081/641997

Metallothionein can make some conditions worse and some better based on the type of cytokines being produced. This is why we must do our research and base the protocol we develop on our own unique bodies physiological profiles. This also shows the importance of maintaining our zinc levels because it is involved in signaling in the immune system.

https://academic.oup.com/jid/article/182/Supplement_1/S62/2191506

Vaccinations and autoimmunity.

They shoot toxins and pathogens directly into the blood stream and they still don’t know how the immune system works. There is no valid science surrounding vaccinations. Those who get vaccinated are the figurative lab rats. The government has never research the safety of vaccinations which they are required to do by law. The dangerous impact vaccine have on our health has been well studied and documented. The vaccine manufactures were having to pay so much out for the injuries and death that occurred the government passed a bill to protect them from the harm they do. They are not required to test the vaccines for safety but the government is supposed to. They illegally have never tested them for safety or even tracked their safety record. To keep the vaccine manufactures from going bankrupt they had to setup the vaccine injury compensation fund which pays out millions a year. The government themselves admit that most vaccine injury goes unreported. Most likely because doctors have no training concerning vaccinations. They do not know what is in them or how to identify vaccine injury and probably never will be because much of the major educational institutions are heavily funded by the pharmaceutical companies.

Because vaccinations are based on theories that have been proven wrong they cannot work and will only cause more illness that are more virulent . They cause things that usually help us and do good for the body to become pathogens. I could post hundreds of studies showing that vaccine make pathogens more virulent.

http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002198

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367402/

https://wwwnc.cdc.gov/eid/article/20/4/13-1478_article

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409122/

They cause autoimmune issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782231/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416069/

https://bmcimmunol.biomedcentral.com/articles/10.1186/s12865-016-0151-2

http://www.pnas.org/content/111/2/787.long

Vaccinations damage the immune system causing an improper immune response.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209321/

https://www.ncbi.nlm.nih.gov/pubmed/21880755

Vaccines can cause self antigens causing the body to turn on itself.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782231/

When he body turns on itself it can result in a variety of illnesses.

https://cdn2.hubspot.net/hubfs/519118/Content%20Offerings/Summary%20of%20Studies%20Featured%20in%20Vaccines%20and%20Autoimmunity%20.pdf

Diabetes has been linked to vaccinations and their effects on T cells.

https://zenodo.org/record/1034775#.W067rteYXMp

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1464-5491.2011.03391.x

Mercury is still used in some vaccines. It causes an immune system imbalance.

https://medel-la-production.s3.amazonaws.com/uploads/attach_document/document_file/59ad883a69702d6c01e71100/Effect_of_thimerosal_in_Jurkat_t_cell_line.pdf

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092705

How vaccines may cause autoimmunity through molecular mimicry.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266166/

Many vaccines contain the OspA and it is how Lyme disease and Ebola causes autoimmunity.

http://www.jimmunol.org/content/166/8/5286.long

Studies like this make me laugh because science has shown that B cell or T cell responses do not indicate or cause immunity.

https://academic.oup.com/jid/article/208/1/1/796926

Vaccinations can damage the lungs.

http://jvi.asm.org/content/77/18/9831.short

https://www.sciencedirect.com/science/article/pii/S0264410X06013235?via%3Dihub

T Cell response does not impart immunity.

https://www.atsjournals.org/doi/abs/10.1164/rccm.201003-0334OC?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed

Those who did not get the Flu shot had a better immune response.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067073/

This is a common theme, vaccinations do not give immunity.

http://www.pnas.org/content/111/2/787

https://www.nejm.org/doi/full/10.1056/NEJMoa1200850#discussion=&t=articleTop

An imbalance in T Cell response is involved in COPD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226027/

Inflammation causes T cell imbalances, T regulatory cells help balance the immune response. Increasing T reg cells helps with COPD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143167/

Inflammation is involved in almost all autoimmune disorders including COPD and asthma.

https://www.jacionline.org/article/S0091-6749(16)30362-1/fulltext

The flu vaccine is one of the ones that causes the most vaccine injuries.

https://medium.com/@andreangelantoni/there-are-several-significant-errors-the-doctor-includes-in-her-article-6dfc196afd9b

If you read this study and compare it to how vaccines are supposed to work you will see that vaccine research in itself is showing it causes autoimmune dysfunction it does not give immunity. Inflammation and many of the cytokines used to determine autoimmune disease are the very same markers vaccine makers use to claim their vaccines are producing immunity. In actuality they are producing autoimmunity.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449453/

Inflammation and autoimmunity

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753746/

Instead of getting the flu shot take some vitamin D.

http://healthimpactnews.com/2017/study-vitamin-d-is-more-effective-than-flu-vaccine/

Vaccinations can cause antiphospholipid syndrome which pretty much means the whole body has turned on itself.

http://journals.sagepub.com/doi/abs/10.1177/0961203311429816?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

Vaccinations can cause brain swelling, inflammation is involved in autoimmunity, which is life threatening and is also one of the main symptoms of autism. Autism has the markers of an autoimmune disorder.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152158/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535916/

https://www.ncbi.nlm.nih.gov/pubmed/16512356/?ncbi_mmode=std

https://www.nature.com/articles/nature18626

Mycoplasmas which cause autoimmunity have been found to be a contaminant in vaccines. There are many types of mycoplasma making it nearly impossible for them to test for contamination. The government says that is acceptable risk. Mycoplasmas can be deadly, especially when injected directly into the body.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207559/

https://www.sciencedirect.com/science/article/pii/S1045105696900524?via%3Dihub

Infection and Cancer.

Lyme disease is often mistaken for T cell lymphoma. Kind of explains why doxycycline reduces cancer.

http://www.zora.uzh.ch/id/eprint/108438/

Human T cell leukemia virus.

http://jvi.asm.org/content/75/9/4420.long

Often times throughout history vaccinations have been found to be contaminated with pathogens that either appear to be cancer or cause cancer.

https://www.sciencedirect.com/science/article/pii/S1045105602000945?via%3Dihub

Some people got vaccinated with vaccines that were contaminated with cancer causing SV40 which also cause HIV like symptoms.

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1750-3639.1999.tb00207.x

https://www.ncbi.nlm.nih.gov/pubmed/15202523/?ncbi_mmode=std

Carcinogen list, the irony of it is many of what they lasted have been found to be contaminants in vaccines, even some of the viruses.

https://www.nih.gov/news-events/news-releases/seven-substances-added-14th-report-carcinogens?fref=gc

Cancer can be from immune issues which we know vaccinations cause, now add an infection to the picture and because the body cannot respond properly you end up with cancer.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712330/

Some infections protect us from cancer.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692468/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006373/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206105/

http://jem.rupress.org/content/214/10/2843

https://www.bmj.com/content/330/7503/1294

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692468/

https://www.lrjournal.com/article/S0145-2126(05)00466-2/abstract

http://www.ener-chi.com/articles/how-infection-can-prevent-and-cure-cancer/

What Th1 and Th2 are.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC27457/

Information on balancing Th1 and Th2.

https://autoimmunewellness.com/how-do-you-balance-th1-and-th2-in-autoimmune-disease/

https://thyroidnation.com/th1-th2-connection-immune-system/

Diet can contribute to autoimmunity.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034518/

There is a big fuss about Cannabinoids but some of them inhibit IL-2 which can have the same effects as too much Omega 6 . It can cause an imbalance in the immune system making us more susceptible to certain infections.

http://molpharm.aspetjournals.org/content/53/4/676.long

http://jvi.asm.org/content/88/21/12452.full

Now where cannabinoids may be helpful is if we have have high B cell and T cell levels.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206973/

Just as this study has found. After reading a lot of research, I have come to realize that there are other things involved in repairing the immune system. We must increase T Reg cells, reduce inflammation, address any infections or/or toxins and correct any metabolic issues.

http://diabetes.diabetesjournals.org/content/61/1/14

Th17 , high levels are common in psoriasis, lupus and interstitial cystitis.

TH17 imbalance is common in those with psoriasis and interstitial cystitis.

https://drknews.com/nitric-oxide-modulation-for-autoimmune-disease/#

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137509/

Pretty much any skin disorder is caused by high TH17 levels. It causes a hapten response which causes the body to attack itself. High Th17 levels is a sign of systematic inflammation

https://www.hindawi.com/journals/jir/2013/261037/

https://www.sciencedirect.com/science/article/pii/S0022202X15336733

Vitamin D helps reduce Th17 levels. Those who have psoriasis, lupus or interstitial cystitis usually have high Th17 levels.

http://www.jbc.org/content/285/50/38751.full

Th17 and neurological issues.

https://www.hindawi.com/journals/ecam/2011/548086/

Those with inflammatory bowel disorders have been found to have high Th17 levels.

https://www.annualreviews.org/doi/full/10.1146/annurev-pathol-011110-130318#_i21

Berberine reduces Th1 and Th17

http://www.jimmunol.org/content/185/3/1855

High levels of Th17 indicate systematic inflammation. This can lead to hashimoto syndrome.

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-3083.2010.02425.x

Inflammation can cause glycolysis issues which will cause Th17 issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5712044/

Th17 is involved in Sjorgren’s Syndrome.

https://www.ima.org.il/FilesUpload/IMAJ/0/254/127219.pdf

Nitric oxid and TH17, I did a post on nitrosative stress.

https://drknews.com/nitric-oxide-modulation-for-autoimmune-disease/#

Red Gensing and vitamin C can help with those who have vaccine induced lung injury.

https://onlinelibrary.wiley.com/doi/abs/10.1111/jphp.12529

Chealation and autoimmunity.

https://drknews.com/chelation-autoimmunity/

Lupus and B cells.

https://arthritis-research.biomedcentral.com/articles/10.1186/s13075-017-1438-2

Histamine can be involved in autoimmunity.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938197/

The problem with this study is that it is pretty much invalid. They use folate which is natural interchangeably with folic acid which is man made. The body does not have issues with folate but our bodies only produce a small amount of the hormones needed to break down man made folic acid. The rest goes into our blood stream causing issues with many receptors in the body and it increases our risk for cancer. The environmental factor they are missing in this study is probably that they were using folic acid instead of folate. The way they used the terms interchangeably made it difficult to tell by the study which they really meant. But issues with the folate cycle can cause immune issues. In my opinion it is most likely from high levels of folic acid.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703744/

Lyme has many ways to avoid the immune system. One of them is by manipulating the immune system.

http://journals.plos.org/plospathogens/article?id=10.1371%2Fjournal.ppat.1002066

Bile acids play a role in our immune system. Oxidative stress and inflammation can inhibit bile acid which would effect our immune system.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426628/

Some viruses play a role in our immunity and protect us from other viruses.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499065/

This study shows interstitial cystitis is an autoimmune disorder. I would not recommend the drug in the study though because many with IC have sulfite issues so this drug could make some worse.

https://www.jurology.com/article/S0022-5347(05)66981-9/fulltext

Getting infections when younger protects us from similar infections but vaccinations have been shown to actually hinder immunity towards similar infections.

http://newsroom.ucla.edu/releases/childhood-flu-infections-provide-protection-against-influenza-pandemics-scientists-report

Inflammation

Inflammation is involved in immune dis-regulation. Vaccines are designed to cause inflammation. The types of adjuvants they use can stay in the body for years. Many that irritant to the cells will be there for a very long time. Imagine what this would do to the body over the years.

https://www.sciencedirect.com/science/article/pii/S0264410X16302559?via%3Dihub

Aluminum which is used in vaccines. is one of the contributing factors to all the neurological diseases now days.

https://www.hindawi.com/journals/jt/2014/491316/

https://www.nature.com/articles/nm.2403

Milk Thistle helps with autoimmunity.

https://pubs.acs.org/doi/10.1021/acs.jnatprod.5b00288

Back Sativa helps because it reduces inflammation and oxidative stress.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884216/

Lactoferrin helps stabilize the immune system.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143167/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143167/

DHEA helps with Addison’s disease.

https://onlinelibrary.wiley.com/doi/full/10.1002/eji.200526128

Stimulating IL 10 and IL 12 helps to clear the OspA . OspA is found in many pathogens and vaccines and is know to cause autoimmunity.

https://www.frontiersin.org/articles/10.3389/fimmu.2014.00310/full

Because NAFLD is an autoimmune disorder and isoflavones help stabilize the immune system it helps with NAFLD.

https://www.sciencedirect.com/science/article/pii/S0091743511005202

Those who have been damaged by antibiotics , GMOs or glyphosate,or glufosinate and have become gluten intolerant may be able to eat sour dough bread. GMOs, vaccinations and farm chemicals raise zonulin levels which cause leaky gut. That causes things like gluten and gliaden to become irritants.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1932817/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273010/

https://link.springer.com/article/10.1007%2Fs10875-012-9745-5

IL 35 helps restore B cells in type 1 diabetes. IL 35 is a T regulatory cell which modulates the immune system and keeps it at homeostasis. So increasing T reg cells would raise IL 35 levels.

http://care.diabetesjournals.org/content/40/8/1090.long

http://care.diabetesjournals.org/content/35/3/465

Increasing IL 35 can cause cancer so increasing T reg cells is the safest way to go.

https://www.sciencedirect.com/science/article/abs/pii/S1043466614002075

It is very important to reduce inflammation also because inflammation causes a reduction in IL 33.

http://europepmc.org/abstract/MED/18787100

Vitamin D3 also helps with diabetes.

https://www.nature.com/articles/srep10411

Curcumine helps with diabetes but it chelates iron so I should be used in moderation because taking it too often can cause anemia.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176754/

mTOR play a huge role in the immune system.

https://www.selfhacked.com/blog/mtor-natural-mtor-inhibitors/

How infection effects the immune system causing inflammation, which can lead to autoimmunity.

https://www.cell.com/cell-reports/fulltext/S2211-1247(17)30933-6

http://www.bio.davidson.edu/people/sosarafova/assets/bio307/meprasse/page05.html

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753746/

A way to detect sepsis.

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180554

Same markers found in Arthritis.

https://febs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1742-4658.2004.04489.x

Causes sepsis through inflammation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2533795/

Levels are high in those with cystic fibrosis because of a change in bacteria in the throat.

https://www.nature.com/articles/ncomms6105

The irony of it is and they do not see this , if levels are still high the body is fighting an infection. So sepsis again is a symptoms which allopathic medicine only looks at. They do not look for the cause so they can correct it.

https://www.nature.com/articles/ncomms6105

Anthrax disables the bodies ability to produce it.

http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.0030187

It suppresses the immune system so would help those with an over active immune system.

http://www.pnas.org/content/106/28/11673.long

Green algae increases SPA2

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2013000400010

Olive Oil reduces it.

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091282

Studies have shown that negative epigenetic changes we aquire throughout life can be passed to our children. That is why it is important to address them and when possible correct them. In the cause of this cut microbiome we would most likely need to support FUT2 enzymes to get this bacteria to establish. There are bacteria that do that. Obesity is an inflammatory conditon, so it could be considered an autoimmune disorder.

https://www.cell.com/cell/fulltext/S0092-8674(14)01241-0

IL-22 stimulates FUT2 so those who lack bacteria that require us to secrete FUT2 enzymes are probably deficient in the bacteria that stimulate increase IL-22. FUT2 also modulates our immune system so we could develop autoimmunity if we are deficient in the bacteria that produce FUT2

https://www.sciencedirect.com/science/article/pii/S1074761313003312

Getting sunlight is important for immune homeostasis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156047/

Those with the lest amount of sun exposure have the highest mortality rates.

https://onlinelibrary.wiley.com/doi/abs/10.1111/joim.12251

Anemia can be an autoimmune disorder caused by cobalamin deficiency.

http://www.discoverymedicine.com/Thein-H-Oo/2017/09/challenging-clinical-presentations-of-pernicious-anemia/

Type of cytokines produced in autoimmunity determines which parts of the body are effected. It is not as simple as Th1 or Th2.

https://arthritis-research.biomedcentral.com/articles/10.1186/ar432

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416069/

In some cases parasite cleanses can make autoimmune conditions worse.

http://www.acupuncturebrooklyn.com/alternative-health/why-a-parasite-cleanse-can-make-you-worse

Oxidative stress and t cells. Notice the common tie. Oxidative stress causes inflammation.

https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-015-0194-3

https://www.cell.com/current-biology/fulltext/S0960-9822(14)00326-1

If you read this study you will see how vaccination cause oxidative stress which causes autoimmunity.

http://experimentalvaccines.org/wp-content/uploads/2015/02/86-Research-Papers-Supporting-the-Vaccine-Autism-Link.pdf

A summarization of things that can cause autoimmunity.

https://doctordoni.com/2018/03/reverse-autoimmunity/

http://www.completenutritionandwellness.com/common-ailments/autoimmune-disorders/

https://www.hindawi.com/journals/omcl/2015/631927/

We have viral genes in us that protect us from illness but when something disrupts them they can make us ill.

https://www.frontiersin.org/articles/10.3389/fmicb.2018.00462/full

http://www.jimmunol.org/content/jimmunol/176/12/7636.full.pdf

https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4901-9

It gets better we also have genes from hookworms in us.

http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0000035

Now we address nutrient deficiencies and their role in autoimmunity.

https://www.amymyersmd.com/2018/04/6-key-nutrient-deficiencies-linked-to-autoimmunity/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292330/

Metallothonein helps protect us from cancer by reducing oxidative stress caused by toxins. It also helps remove heavy metals from the body.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634463/

http://www.cease-therapy.com/treatment/metallothionein

https://www.sciencedirect.com/science/article/pii/S0041008X05800171

https://biofoundations.org/inducing-metallothionein-for-heavy-metal-detoxification-and-reducing-oxidative-stress/

Now lets see what could cause modern day nutrient deficiencies.

Genetically modified foods contain less nutrients.

http://farmandranchfreedom.org/wp-content/uploads/2014/01/glyphosate-accumulates-roundup-ready-gmo-soybeans.pdf

Rats feed GM foods died sooner.

http://www.ijbs.com/v05p0706.htm

Glyphosate used on GMOs chelates minerals from the body and is found in most of our food suppley.

https://www.omicsonline.org/field-investigations-of-glyphosate-in-urine-of-danish-dairy-cows-2161-0525.1000186.php?aid=18383

If you really want to see the harm they do read this information.

https://www.gmwatch.org/en/news/latest-news/17483

http://seattleorganicrestaurants.com/vegan-whole-food/allergies-chlorinate-tap-water-GMOs.php

Hyper Excitement of NMDA (autism also known as encephalitis)

This is not medical advice I am posting this for informational and educational purposes.

stock-photo-concept-of-human-intelligence-with-human-brain-on-blue-background-294471983

The NMDA receptors in the brain is one of the most effected when we are ill. It can cause blurred vision, trouble with light it will glare to those effected. You may get buzzing in the ears. It can cause bipolarism, autism , schizophrenia, dissociative behavior and tunnel vision among many other issues.

Most things like metabokic issues , oxidative stress, autoimmunity that I mention in here I have posted on and you can find it using the search feature in my blog.

NMDA Receptors

Information on how the NMDA receptor functions.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1760733/

L-glutamate or glutamic acid is one of the most important of the excitatory neurotransmitters. It is released by many different types of neurons and stimulates other neurons at the synapses. The excitatory neurotransmitters act to stimulate the next neuron to fire.

Excitotoxicity is when levels of excitatory neurotransmitters are to high, at which point the level of neuronal activation or induced firing of neurons becomes damaging.

GABA inhibits firing of neurons. GABA is synthesized from glutamine. It needs the active form of B6, pyridoxal phophate. When there have been inhibitions in metabolic pathways the body may not be able to convert the B6 to the active form causing a build up of glutamine or glutamate. This can lead to dysfunction in the brain. It can also lead to high ammonia levels. Raised ammonia levels can kill our good gut bacteria and let the sulfur digesting and methane producing bacteria increase in numbers. This will also happen in the bladder. Also high ammonia levels will make candida go from commensal to pathogenic form. This will cause high sulfite levels which will interfere with BH4, I discussed earlier the problems that creates. The high sulfite levels can also cause problems with the CBS pathway which can eventually effect the Krebs Cycle.

GABA and glutamate are balanced in the brain . P5P deficiency can result in elevated glutamate to GABA ratio in the brain which results in elevated levels of exitotoxicity.

https://www.ncbi.nlm.nih.gov/pubmed/17127302

Taurine performs manby vital functions in the body including nutritional metal transport into the cells.

L-glycine is an inhibitor of neurotransmitter.

N-Methyl-D-Aspartate (NMDA) receptors found in various nerve cells or neurons in the brain. They are stimulated by glutamate and aspartate (aspartic acid). There are 4 main types of of neurotransmitters. NMDA, AMPA, Kainate and Metabotropic receptors.

NMDA primary role is to respond to glutamate or aspartate. NMDA is also stimulated by glycine and polyamines. Aspartate is also involved in the Krebs cycle. Polyamines are interesting, they do not know a lot about them but from what I have read they are almost like software that will zip or compress files then decompress them. They also have a lot of other functions.

Post synaptic NMDA receptor hyper excitement by the presence of elevated glutamate and aspartate levels and/or insufficient GABA, Taurene or Glycine levels results in the receptor opening a channel in the cell membrane allowing the influx of calcium (Ca2+) ions and a reduction of potassium (k+) ions. This has been linked to many brain disorders and it is a common theme in a variety of disorders effecting the brain. The influx of calcium into the cells stimulates NOS leading to NO production in post synaptic cells. I discussed eNOS and iNOS in my post on Nitrosative Stress. Most of the NO production in the NMDA receptor is from nNOS. This can increase peroxynitrite levels because of elevated superoxide levels from oxidative stress. This can damage the brain and blood brain barrier. This can also deplete ATP , when ATP levels are low the NMDA receptors become hyper sensitive.

When the NMDA receptor is hyper sensitive a person will become sensitive to many thing, sound, light, certain odors especially toxic ones. It can make a person sensitive to chemicals because of the over stimulation.

problems with the NMDA recptor can cause the immune system to be inhibited

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586474/

NMDA issues can also have effects on the heart.

https://www.ncbi.nlm.nih.gov/pubmed/27561785

There is a connection between the NMDA receptor and pancreatic cancer.

https://www.dovepress.com/nmda-receptors-are-important-regulators-of-pancreatic-cancer-and-are-p-peer-reviewed-article-CPAA

Issues with the NMDA receptors can result in chemical sensitivities.

https://www.ncbi.nlm.nih.gov/pubmed/12205032

Copper moduclates the NMDA receptor. When we have an infection our bodies will hide copper in our soft tissue. This can make us appear to be deficient in copper. Vitamin C frees the copper from our soft tissue. Do not take too much, in high doses vitamin C destroys red blood cells. If you are deficient in copper liquid chlorophyll is a good source of copper.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382327/

https://www.hindawi.com/journals/ijad/2011/292593/

https://www.hindawi.com/journals/omcl/2014/147251/

Vitamin C interacts with the NMDA receptor to reduce pain. Has been shown to help with sciatica.

https://www.ncbi.nlm.nih.gov/pubmed/28902622

Most know vaccinations damage the brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297824/

http://n.neurology.org/content/86/16_Supplement/P5.136

https://www.ncbi.nlm.nih.gov/m/pubmed/25081016/?i=5&from=%2F26844739%2Frelated

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936221/

It is a good idea to learn the symptoms because damage to the NMDA receptor is common in those vaccinated.

http://pediatrics.aappublications.org/content/138/3/e20160901?download=true

http://www.sciencedirect.com/science/article/pii/S2214250914000262

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297824/

Information on NMDA and supplements that help with NMDA issues.

https://www.wellnessresources.com/news/when-ssris-fail-causes-of-depression-nutrition-for-your-brain

Magnesium and Zinc helps to counter the influx of Ca2+ from the NMDA stimulation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122891/

Restless legs has been caused by high glutamate levels.

http://www.rlcure.com/glutamate.html

High ammonia levels will cause high glutamate levels.

http://www.ucl.ac.uk/~ucbcdab/urea/amtox.htm

Oxidative stress.

https://www.sciencedirect.com/science/article/pii/S1011134417307030?via%3Dihub

https://www.ncbi.nlm.nih.gov/pubmed/16766163

https://www.ncbi.nlm.nih.gov/pubmed/24814387

http://thescipub.com/html/10.3844/ajbbsp.2008.73.84

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881419/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965765/

How the body regulates glutamate levels and how to protect the brain.

https://www.ncbi.nlm.nih.gov/pubmed/26711497

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431845/

http://nancymullanmd.com/glutamate-and-gaba-balance/

http://www.holistichelp.net/blog/how-to-increase-gaba-and-balance-glutamate/

http://www.jneurosci.org/content/25/26/6084

http://dana.org/Cerebrum/Default.aspx?id=39382

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134390/

http://journals.sagepub.com/doi/pdf/10.1177/0300060517693423

https://www.ncbi.nlm.nih.gov/pubmed/25433158

The blood brain barrier.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687937/

Glyphosate, this has been found to be in very high levels in our food supply. They have found the environment is so contaminated that it is even in the air and rain. So almost all have glyphosate in them.

https://www.ncbi.nlm.nih.gov/pubmed/28627408

https://www.sciencedirect.com/science/article/pii/S0300483X14000493

Inflammation

https://neuroshaman.wordpress.com/2016/01/23/kynurenic-acid-a-factor-for-schizophrenia-and-autism/

BH4 and autism.

https://autismmasterycourse.com/wp-content/uploads/2016/08/Neurochemical-Imbalances-and-Autism-Tetrahydrobiopterin-Metabolism-and-Quinolinic-Acid-Toxicity.pdf-8-15-16.pdf

The NMDA receptor has been tied to interstitial cystitis.

http://inter-use.com/Journals/JSAB/2015/Volume_03_Issue_04/2015/0507/96.html

Brain and gut.

https://www.wellnessresources.com/news/when-ssris-fail-causes-of-depression-nutrition-for-your-brain

https://link.springer.com/article/10.1007/s00787-017-1056-1

https://www.ncbi.nlm.nih.gov/pubmed/9881820

https://www.ncbi.nlm.nih.gov/pubmed/29090837/

https://www.ncbi.nlm.nih.gov/pubmed/20359266

https://www.nature.com/articles/nature22075

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068444

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879184/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228144/

https://www.selfhacked.com/blog/gut-bacteria-microbiome/?utm_source=ActiveCampaign&utm_medium=email&utm_content=ICES%2FPEMF%2C+Ceylon+Tea%2C+Gut+Microbiome+Affects+%2B+Management%2C+Purple+Sweet+Potato%2C+Myostatin%2C+Hyperbaric+Oxygen+Therapy&utm_campaign=Mar42018+Newsletter

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040025/

https://www.cell.com/cell/fulltext/S0092-8674(15)00248-2

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169303

https://www.researchgate.net/publication/312447778_Lactobacillus_plantarum_CCFM639_can_prevent_aluminium-induced_neural_injuries_and_abnormal_behaviour_in_mice

https://thevaccinereaction.org/2016/09/role-of-the-microbiome-in-infant-development/

https://www.ncbi.nlm.nih.gov/pubmed/18283240

https://kresserinstitute.com/gut-circadian-rhythm-connection/

https://www.honeycolony.com/article/trust-your-gut-health/

http://www.greenmedinfo.com/blog/vaccine-injury-first-gut-then-brain

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572414/

GMOs and the farm chemicals used on them cause leaky gut. This is a cause of autism.

https://molecularautism.biomedcentral.com/articles/10.1186/s13229-016-0110-z

https://www.theunion.com/news/twi/glyphosate-roundup-and-its-link-to-celiac-disease-gluten-intolerance/

https://detoxproject.org/glyphosate/glyphosate-and-roundup-negatively-affect-gut-bacteria/

http://autismcoach.com/glyphosate-folic-acid-oxalic-acid-vaccines-and-tylenol-wreak-metabolic-havoc-together/

https://www.ncbi.nlm.nih.gov/pubmed/25883837

https://www.cell.com/cell/fulltext/S0092-8674(16)30730-9

http://journals.sagepub.com/doi/pdf/10.1177/0300060517693423

Getting GMOs out of the diet helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550406/

http://www.autismone.org/content/autism-explained-synergistic-poisoning-aluminum-and-glyphosate-stephanie-seneff

https://www.youtube.com/watch?v=kzHXuMIsZTA

http://www.mdpi.com/1099-4300/15/4/1416

Our toxic food.

https://bebrainfit.com/neurotoxins-foods/

https://chriskresser.com/beyond-msg-could-hidden-sources-of-glutamate-be-harming-your-health/

http://www.holistichelp.net/toxins.html

https://www.dementia.org/study-links-diacetyl-to-alzheimers-disease

https://www.sciencedirect.com/science/article/pii/S0300483X14000493

Our parents past can have effects on our brain.

https://www.whatisepigenetics.com/a-fathers-stress-felt-for-generations/

https://www.madinamerica.com/2013/05/starvation-what-does-it-do-to-the-brain/

http://europepmc.org/articles/PMC4333222

How infection causes NMDA issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635055/

https://www.ncbi.nlm.nih.gov/pubmed/28484451

Our environment.

https://www.ncbi.nlm.nih.gov/pubmed/26721368

http://www.chemtrust.org/brain/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914412/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428475/

Proton Pump inhibitors damage the brain.

https://jamanetwork.com/journals/jamaneurology/fullarticle/2487379?utm_source=facebook&utm_medium=social_jamaneur&utm_campaign=article_alert&utm_content=automated

Endotoxins can contribute to NMDA excitability. Astaxanthin helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746928/

https://docs.google.com/document/d/19UH1Jfe0qlPrKunC36yZVXZcuRLx_f8MslQdSXkV8pA/mobilebasic

https://autismrecoverytreatment.com/autism-treatment-–-quinolinic-acid-and-autism/

A number of autism studies and causes.

https://medel-la-production.s3.amazonaws.com/uploads/attach_document/document_file/59cda6fe69702d2351c80600/autism-studies-april-2008-2.pdf

Over active immune response which can be caused by tick born illness, vaccinations or glyphosate.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921406/

Inflammation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753746/

http://www.cytokines-and-depression.com/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535916/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961620/

Inflammation from Lyme can even cause aneurysms.

https://jnnp.bmj.com/content/64/5/636

https://www.madinamerica.com/2017/03/lyme-wake-up-call/#comment-125698

https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-5-40

https://www.ncbi.nlm.nih.gov/pubmed/24604078

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481283/

https://www.linkedin.com/pulse/your-brainon-lyme-lori-dennis-ma-rp/?trk=prof-post

Oxidative stress

http://www.eurekaselect.com/101108/article

Immune system

https://reliawire.com/immune-system-social-behavior/?utm_content=buffer5f170&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer

https://www.ncbi.nlm.nih.gov/pubmed/23867105

http://neurosciencenews.com/schizophrenia-immune-disorder-bipolar-8179/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143489/

Encephalitis is part of the illness.

https://aealliance.org/patient-support/symptoms/

http://www.pandasnetwork.org/wp-content/uploads/2013/07/Autoimmune_encephalitis.pdf

Brain being deprived of cholesterol. This shows how statins cause it but metabolic issues can also cause this.

https://www.westonaprice.org/health-topics/modern-diseases/dangers-of-statin-drugs-what-you-havent-been-told-about-popular-cholesterol-lowering-medicines/

https://www.medicalnewstoday.com/articles/321115.php

http://www.greenmedinfo.com/blog/underreported-dangers-low-cholesterol

https://www.theautismexchange.com/organized-information/biomedical/conditions/low-cholesterol

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005588/

https://www.ncbi.nlm.nih.gov/pubmed/?term=PMC5806328

https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-016-0877-8

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487843/

This I have researched it is caused by oxidative stress from toxins.

https://www.medel.la/card_collections

Fluoride damages the brain.

https://www.researchgate.net/publication/291795479_Effects_of_endemic_fluoride_poisoning_on_the_intellectual_development_of_children_in_Baotou

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997496/

https://www.hsph.harvard.edu/news/features/fluoride-childrens-health-grandjean-choi/

https://www.ncbi.nlm.nih.gov/pubmed/25577494

https://www.ncbi.nlm.nih.gov/pubmed/25556215

Fluoroquinolone drugs destroy the brain.

https://floxiehope.com/2015/06/13/hacking-fluoroquinolone-toxicity-via-the-nervous-system/

Reversing autism

https://www.youtube.com/watch?v=m2PyRhOSYBY

http://healing-arts.org/children/mtpromotion.htm

Certain metabolic issues caused by toxins, infection or nutrient deficiencies can cause high ammonia levels which can lead to brain injury. These can be caused by nutrient deficiencies, toxins, vaccine injury, inflammation, over active immune system or infection. Many studies have connected metallothionein deficiency with autism.

http://www.neuroradiologycases.com/2012/02/hyperammonemic-encephalopathy-mri.html

https://academic.oup.com/ajcn/article-abstract/80/6/1611/4690493?redirectedFrom=fulltext

http://www.cease-therapy.com/treatment/metallothionein/

https://epidemicanswers.org/metallothionein-and-autism-2/

https://www.psy-journal.com/article/S0165-1781(13)00737-3/fulltext

https://www.hindawi.com/journals/omcl/2017/5828056/abs/

These metabollic issues can be caused by vaccine injury and glyphosate.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028461/

https://www.ncbi.nlm.nih.gov/pubmed/17127302

https://www.westonaprice.org/health-topics/environmental-toxins/violent-behavior-a-solution-in-plain-sight/

https://www.tandfonline.com/doi/abs/10.1080/1028415X.2017.1423268?journalCode=ynns20

Low CoQ10 can contribute but under certain circumstances it could increase oxidative stress making things worse. So I would so address the issues causing the low CoQ10 before taking it.

https://www.ncbi.nlm.nih.gov/pubmed/20010493

Mast cell activation can cause a number of illnesses.

http://www.mastcellaware.com/mast-cells/related-conditions.html

https://www.prohealth.com/library/study-shows-that-mast-cell-activation-a-disorder-common-in-lyme-disease-causes-depression-5478

http://planetthrive.com/2010/12/the-alkaline-brain/

Spinal fluid leak can be caused by fluoroquinolones or tick born illness.

http://spinalcsfleak.org/

Mercury can cause problems with the NMDA receptor. They claim it is not in vaccinations but that is a lie some still contain it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241260/

https://www.nature.com/articles/4001529

They try to blame genetics for mercuries effects on the NMDA receptor.

https://www.nature.com/articles/4001529

Serine helps.

https://pubs.acs.org/doi/10.1021/acs.jafc.7b04217

vitamin B6 helps by reducing brain inflammation.

http://www.hormonesmatter.com/reducing-brain-inflammation-vitamin-b6/

Ashwanga enhances memory through the NMDA receptor.

https://www.ncbi.nlm.nih.gov/pubmed/23711138

If the body is not producing enough endocanabinoids , phytocanabinoids my help.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342457/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877778/

Sarcosine helps with NMDA issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921092/

https://jamanetwork.com/journals/jamapsychiatry/fullarticle/209027

D3 also helps reduce psychosis through the NMDA receptor.

https://www.ncbi.nlm.nih.gov/pubmed/12842123

Those with anti-NMDA antibodies have been found to be low in vitamin D.

https://www.ncbi.nlm.nih.gov/pubmed/27836631

The NMDA receptors help regulate glucose homeostasis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903398/

http://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(15)00248-9

Fasting reverses some aging in the brain through NMDA.

http://www.jneurosci.org/content/27/38/10185

PQQ helps with nuerotoxic injury.

https://www.ncbi.nlm.nih.gov/pubmed/1318959

https://michaelrucker.com/glutamate/pqq-glutamate-nitric-oxide-and-n-methyl-d-aspartic-acid-receptors/

Cat’s Claw helps with NMDA issues.

https://www.ncbi.nlm.nih.gov/pubmed/15531384?dopt=Abstract

Not sure what Acorus is but it helps with NMDA issues.

https://www.ncbi.nlm.nih.gov/pubmed/11253173?dopt=Abstract

Psychotria Colorata helps with NMDA issues and opioid addiction.

https://www.ncbi.nlm.nih.gov/pubmed/11417913

Huperzia serrata contains huperizine A which helps with alzheimer’s

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137276/

Aspertame an atrificial sweetener can cause damage to the NMDA receptors.

https://www.globalhealingcenter.com/natural-health/health-dangers-of-aspartame/

MSG also has a negative impact on the NMDA receptors.

https://www.researchgate.net/publication/303458692_The_effects_of_monosodium_glutamate_and_aspartame_on_rat_hippocampal_N-methyl-D-aspartate_receptor_subunits_and_oxidative_stress_biomarkers

Muscarinic

Muscarinic receptors are G-protein (molecular switches) coupled acetycholine receptors. They are found on the outer membrane of certain neurons and cells. There are five types of Muscarinic Acetylcholine receptors (mACHRs). M1-M5 , when the odd numbered receptors are stimulated they produce increased levels of cytoplasmic (material within a cell) calcium ions in the cell. The odd number receptors trigger synthesis of a chemical messenger IP3 (inositol triphosphate-a phytate) which releases intercellular calcium stores from certain calcium stores that have been sequestered away in the cell. The increased cellular calcium concentration will lead to increased NO production by nNOS and eNOS this can lead to high peroxynitrite levels.

Over stimulation of mACHRs from farm chemicals and many other toxins like heavy metals cause high acetycholine levels by inhibiting acetylcholesterase enzyme which breaks down acetylcholine. This causes high levels of acetycholine which causes the release of NO leading to the production of peroxynitrite. Excessive supplementation of DMAE or Centrophenoxine which has a DMAE component can result in elevated acetylcholine. This can also lead to excess inflammation throughout the body because it is involved in reducing inflammation.

High acetylcholine levels can cause anxiety and high risk taking behavior and mood swings.

http://www.pnas.org/content/103/13/5219

Scopolamine found in belladonna can inhibit muscarinic excitability.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285663/

Nutrients for the muscarinic receptors.https://ecommons.aku.edu/cgi/viewcontent.cgi?referer=https://swisscows.com/&httpsredir=1&article=1032&context=pakistan_fhs_mc_bbs

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1471-4159.2011.07616.x

Mugwort helps

https://ecommons.aku.edu/cgi/viewcontent.cgi?referer=https://swisscows.com/&httpsredir=1&article=1032&context=pakistan_fhs_mc_bbs

Tylenol autism.

https://vactruth.com/2016/06/25/acetaminophen-and-autism/

https://safeminds.org/news/data-points-acetaminophen-exposure-children-potentially-inducing-autism/

Psychological Stress or Trauma

Psychological stress or trauma causes high NO levels which can lead to high peroxynitrite levels which is very damaging to the brain and body. iNOS is upregulated in the lungs and liver during stress. High iNOS levels have been found to be common in post traumatic stress disorder and many illnesses involving chronic fatigue. iNOS is also unregulated during physical trauma which makes those who have been abused more susceptible to chronic fatigue disorders.

Vaccinations and NMDA

It is stated on many vaccine inserts that brain swelling is a side effect. Vaccinations have a dramatic impact on the NMDA and Muscarinic receptors causing the above mentioned things. If you look up the symptoms of autism you will see that brain swelling is the main symptom. But the pharmaceutical companies play the rename game. When people start figuring things out they will rename an illness. They now call it encephalopathy. They played this very game when people figured out that Gulf War Syndrome was caused by vaccinations. They now call it ASIA syndrome.

Aluminum is in vaccines.

https://www.frontiersin.org/articles/10.3389/fneur.2014.00212/full

https://www.ncbi.nlm.nih.gov/m/pubmed/6135334/

https://cdn2.hubspot.net/hubfs/519118/Content%20Offerings/Summary%20of%20Studies%20Featured%20in%20Vaccines%20and%20Autoimmunity%20.pdf

http://www.greenmedinfo.com/article/study-found-increased-asd-risk-among-children-whose-mothers-received-influenza

http://www.ageofautism.com/2010/05/peer-reviewed-papers-support-findings.html

https://bmcneurol.biomedcentral.com/articles/10.1186/1471-2377-11-149

https://arupconsult.com/content/n-methyl-d-aspartate-nmda-type-glutamate-receptor-autoantibody-disorders

https://link.springer.com/article/10.1007%2Fs12026-016-8855-1

http://circleofdocs.com/30-solid-scientific-studies-that-prove-vaccines-cause-autism/

https://medel-la-production.s3.amazonaws.com/uploads/attach_document/document_file/59725b7269702d07c0bf0000/Acute_Disseminated_Encephalomyelitis_After_Influenza_Vaccination.pdf

https://www.sciencedirect.com/science/article/pii/S0946672X17308763

https://jbiomedsci.biomedcentral.com/articles/10.1186/1423-0127-19-51

https://www.hindawi.com/journals/jt/2014/491316/

https://www.ncbi.nlm.nih.gov/pubmed/944354

https://www.ncbi.nlm.nih.gov/m/pubmed/24996055/

https://www.ncbi.nlm.nih.gov/pubmed/21058170

https://jamanetwork.com/journals/jamapediatrics/article-abstract/2617988

http://www.globalresearch.ca/mitochondrial-collateral-damage-thanks-to-big-pharma/5447650

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1112717/

https://www.ncbi.nlm.nih.gov/pubmed/15265850

http://www.ageofautism.com/2010/07/new-study-shows-vaccines-cause-brain-changes-found-in-autism.html

https://jamanetwork.com/journals/archneurpsyc/article-abstract/647602#nav

https://www.jocn-journal.com/article/S0967-5868(08)00189-6/fulltext

http://www.vaclib.org/links/jockslinks.htm

They claim mercury has been removed from vaccines but that is a lie because some still contain it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705731/

https://www.ncbi.nlm.nih.gov/pubmed/23843785

https://www.ncbi.nlm.nih.gov/pubmed/16870260

https://www.ncbi.nlm.nih.gov/pubmed/19357975

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70278-3/abstract

https://www.globalresearch.ca/big-pharma-prescribed-drugs-or-vaccine-induced-dementia-is-not-alzheimer/5628607

http://www.greatergoodmovie.org/learn-more/science/brain-inflammation-encephalitis-post-vaccination/

https://www.hopkinsmedicine.org/news/media/releases/brain_inflammation_a_hallmark_of_autism_large_scale_analysis_shows

https://www.ncbi.nlm.nih.gov/pubmed/22015705

https://www.mcleanhospital.org/news/mclean-hospital-neuroscientists-find-immune-system-newborns-may-affect-developing-brain

https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/2047-9158-3-16

https://www.ncbi.nlm.nih.gov/pubmed/21549155

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173748/

https://web.archive.org/web/20150210051051/http://www.ashotoftruth.org/history

Autoimmunity.

http://journals.sagepub.com/doi/abs/10.1177/0961203311429550?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

Toxins cause oxidative stress which leads to brain injury.

https://www.researchgate.net/figure/Methionine-synthase-links-oxidative-stress-to-epigenetic-regulation-Figure-4-shows-how_fig4_223971780

Nutrients that help.

http://www.mdpi.com/2072-6643/10/3/369

Saffron can help with the effects of these things.

https://www.sciencedirect.com/science/article/pii/S094471131400364X?via%3Dihub

https://www.ncbi.nlm.nih.gov/pubmed/21623535

Increasing Ghrelin may help.

https://www.selfhacked.com/blog/ghrelin-role-cognitive-gut-function-weight-inflammation-autoimmunity/

Melatonin helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1571800/

Fish oil helps.

https://draxe.com/fish-oil-benefits-health/

Removing aluminum from the brain.

http://realfarmacy.com/mineral-waters-remove-aluminum-from-brain/

Black Sativa helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642442/

Having pets helps.

https://www.nih.gov/news-events/news-releases/animals-presence-may-ease-social-anxiety-kids-autism

Corn silk helps but must be organic. The BT Toxin and glyphosate in GMOs have been shown to cause autism.

https://innovareacademics.in/journals/index.php/ijpps/article/view/6943

Anise oil helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416669/

orthosilicic acid may help or silica

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546016/

https://www.ncbi.nlm.nih.gov/pubmed/3743228

To increase my brain glycogen levels in the morning I started using maple syrup, honey or organic unsulfured blackstrap molasses.

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1471-4159.2004.02421.x

Luteolin helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490655/

Niacin may help.

http://blog.healthybynaturehwc.com/niacin-deficiency/#comment-1287

Wild violet helps with insomnia.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341349/

Some natural therapies that helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994794/

https://feingold.org/

Ebselem helps by reducing oxidative stress.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759215/

Ferulic Acid found in wheat bran and angelica helps.

https://www.sciencedirect.com/science/article/abs/pii/S0031938416308691

Sulfur and autism.

https://www.blants.com.au/autism.html

Flaxseed increases MAO release which may help.

http://journals.sagepub.com/doi/abs/10.1177/0960327115571765

Tryptophan my help with some but there are certain metabolic issues this could make worse.

https://www.ncbi.nlm.nih.gov/pubmed/11336160

St. Johnswort may help.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736901/

Plants that may help.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597072/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452207/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210916/

Plants that help reduce acetycholine.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518125/

Honeysuckle may help.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492671/

Metallothein helps.

https://metabolichealing.com/metallothionein-forgotten-antioxidant-missing-puzzle-piece-for-alzheimers-leaky-gut/

Lionsmane mushroom helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583117/

Gingko really helped me but the first couple of times I took it, it gave me a headache. It you take it for too long it can damage the liver. But certain vitamins can do that.

https://www.jstage.jst.go.jp/article/bpb/37/2/37_b13-00378/_article

Some herbs that helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459457/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993511/

http://www.encognitive.com/node/6310

Palmitoylethanolamide helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531370/

Baicalein found in sculletaria, fleabane and plantain herb helps. Helped me a lot.

https://www.ncbi.nlm.nih.gov/pubmed/27518088

Hydroxocolbalamin may help.

https://www.prohealth.com/library/the-brain-boosting-and-fatigue-fighting-b-12-26949

Diet for those with phenylketonuria. I fixed mine.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750587/

Thymus found in savory, juniper berries, thyme, black sativa and bergamot will help.

https://www.ncbi.nlm.nih.gov/pubmed/24814387

Passion flower helps but I have seen studies that make me question the safety of it’s long term use. I would only use when needed.

https://www.ncbi.nlm.nih.gov/pubmed/27693740

Self heal helps.

https://onlinelibrary.wiley.com/doi/10.1002/ptr.4929

Pyrroluria is a symptom of porphyria. This will help the pyrroluria part of the symptoms.

https://nutrientpower.wordpress.com/pyrroluria/

For those who have symptoms severe enough to cause convulsions these herbs have been researched.

http://www.eurekaselect.com/152566/article

Tips for reducing brain inflammaton.

http://www.hormonesmatter.com/reducing-brain-inflammation-vitamin-b6/

Rooibos helped me.

https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.201300463

Roseroot helps. Actually I looked at the phytochemicals of the whole plant and they are pretty much the same throughout the plant.

https://www.medicalnewstoday.com/articles/291596.php

Quiet time helps.

https://www.lifehack.org/377243/science-says-silence-much-more-important-our-brains-than-thought?ref=facebook

Serrapeptase and nattokinase helps but very high doses can have serious negative health effects.

http://journals.sagepub.com/doi/abs/10.1177/0960327112467040?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

For better sleep.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008810/

Pyrroloquinoline Quinone helped me a lot with healing.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303106/

N-acetylcysteine helped me.

https://www.optimallivingdynamics.com/blog/the-powerful-antioxidant-proven-to-treat-6-mental-illnesses

Hops was another one that helped me a lot. It has a cannabinoid similar to THC, I react bad to THC but not to hops.

https://akademiai.com/doi/abs/10.1556/APhysiol.99.2012.2.6?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed

God info on healing nerves and the brain.

https://www.selfhacked.com/blog/myelin/

Good info on healing children with autism.

http://www.healourlittleones.com/?p=837

Reducing endothelins can helps, this would also help with high blood pressure.

https://www.selfhacked.com/blog/endothelins/?utm_source=ActiveCampaign&utm_medium=email&utm_content=The+Latest+From+SelfHacked&utm_campaign=Jan282018+Newsletter

Cut toxic people out of your life. If they cared they would not be so toxic.

https://themindsjournal.com/why-its-okay-to-cut-toxic-family-members-out-of-your-life/

Thiamine deficiency can cause many health problems.

https://www.livescience.com/51721-vitamin-b1-thiamine.html

Those who are G6PD deficiency or metabolic issues especially porphyria or sulfation issues need to address them because the foods that contain thiamine could make them ill if they do not. They may have to supplement until they have addressed them.

https://draxe.com/thiamine-foods/

https://www.livescience.com/51721-vitamin-b1-thiamine.html

Folic Acid is man made and not good for the body and can cause problems.

https://www.drbenlynch.com/resource/why-you-should-stop-taking-folic-acid/

http://blog.naturalhealthyconcepts.com/2015/05/13/the-difference-between-folate-folinic-acid-and-folic-acid/

https://www.thehealthyhomeeconomist.com/folic-acid-making-us-sick/

https://www.globalhealingcenter.com/natural-health/difference-between-folate-and-folic-acid/

Folic acid has been linked to cancer. Folate has not.

https://breastcancerconqueror.com/the-hidden-dangers-folic-acid-vs-folate/

the gut and cholestokinin

http://www.yourhormones.info/hormones/cholecystokinin/

https://www.selfhacked.com/blog/good-bad-effects-cck/

Trypsin inhibitors increase cholecystokinin.

https://naldc.nal.usda.gov/download/26115/PDF

Things that raise GABA like , mugwort, wormwood and rooibos reduces cholecystokinin levels. High estrogen levels cause high cholecystokinin levels. High dopamine levels increases cholecystokinin. High levels of cholecystokinin causes glutamate toxicity and NMDA toxicity.

https://www.acnp.org/g4/GN401000056/CH056.html

Potatoes increase cholecystokinin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033477/

If not addressed it leads to autism.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628252/

 

Meditation now called nuero feedback can help heal the brain.

https://www.frontiersin.org/articles/10.3389/fpsyg.2013.00688/full

https://www.selfhacked.com/blog/neurofeedback/?mpweb=1367-178-19862

There are various meditation technique depending on the desired outcome.

https://www.researchgate.net/publication/41486162_Focused_attention_open_monitoring_and_automatic_self-transcending_Categories_to_organize_meditations_from_Vedic_Buddhist_and_Chinese_traditions._Consciousness_and_Cognition_19(4)_1110-1118

https://www.brainsinternational.com/default/assets/File/Phenotype_%20Johnstone,%20et%20al.pdf

Those who meditate have higher cognitive function and less stress.

https://www.goalcast.com/2017/06/20/healing-power-meditation-brain-health/

Meditation even helps with inflammatory bowel disease. It can turn bad genes off.

https://news.harvard.edu/gazette/story/2015/05/meditation-may-relieve-ibs-and-ibd/

https://www.brainline.org/article/role-mindfulness-meditation-and-prayer-after-brain-injury

Nitrosative Stress

This is not medical advice , I am posting this for educational and informational purposes only. This compliments the other post I did on recovering from endotoxemia.

Nitrosative Stress

Is caused by oxidative stress, inflammaton and infection. Those can also lead to Nitrosative Stress which can cause superoxide, and peroxynitrite which are very damaging to the body especially the brain and nervous system. These are a form of Reactive Nitrogen Species. (RNS) Nitric Oxide dependent reactions lead to formation of RNS through the reaction of Nitric Oxide and O2-, peroxynitrite (ONOOH) is formed and leads to oxidation, nitrosation (addition of NO), or nitration (addition of NO2) .

Nitric Oxide is formed from Nitric Oxide Synthase (NOS) which can also produce O2-. Other sources are Xanthine Oxidase, NADPH oxidase, and Myeloperoxidase. There are three types of NOS, inducible nitric oxide synthase (iNOS, NOS2), endothelium NOS (eNOS, NOS3), neuronal NOS (nNOS, NOS1) They no longer use the numerical references to NOS because it inaccurately described them.

Nitric Oxide is a signaling molecule. When functioning properly it is involved with the homeostasis of our blood pressure. Nitric Oxide is released by the endothelial of the smooth muscle to promote smooth muscle relaxation. This increases the diameter of blood vessels to prevent high blood pressure. Oxidative stress and nitrosative stress can deplete NO causing high blood pressure.

Nitric Oxide has antithrombic effects. So if NO is depleted or production is inhibited by free radicals then excessive blood clotting can occur. Impaired NO production can lead to hypertension, preclampsia, diabetes, obesity, erectile dysfunction, and migraine headaches.

NO is generated as a normal part of an immune response. White blood cells known as phocytes have both inducible and inhibitory enzymes to control NO. NO secreted as part of the immune response uses NOS free radical properties and it is toxic to bacteria, causing DNA damage and degredation of the iron sulfur center.

NO increases expression of superoxide dismutase which catalyzes superoxide anion to hydrogen peroxide. NO upregulates Heme oxygenase 1 and ferritin expression which reduce anion concentrations in blood vessels. This prevents blood vessels from leaking. Inflammation , endotoxins, farm chemicals and many other things can inhibit this. This leads to hardening of the arteries because the body will use cholesterol and calcium to plug the leaks.

NO helps convert thiol groups including cysteine residues in proteins, to form s-nitrosothiols. Thiols are organo sulfur compounds. Our bodies need sulfur for many things and all cell need it. If sulfite levels get high from BH4 , CBS issues, gut dysbiosis or candida it could interfere with the proper function of the thiol groups. S-nitrosylation is an important mechanism for dynamic, post translational regulation of most all major classes of proteins. Post translational regulation is control of gene expression.

Guanylyl known as the NO receptor. Activate guanylyl cyclase enables the production of the cyclic guanosine monophosphate (cGMP) . cGMP activates and regulates the enzyme G-kinase. G-kinase modifies proteins in cell through phosphorylation of the myosin light chain kinase which causes smooth muscle relaxation.

Chronic expression of NO can lead to cancer of the epithelium, juvenile diabetes, multiple sclerosis, arthritis, and ulcerative colitis. NO is an oxidising free radical and does cause some oxidative stress on the bodies membranes and tissues. Sustained No production can result in tissue toxicity but most damage is caused from NO causing peroxynitrite formation.

NO protects organs from ischemia, but can contribute to reperfusion injury by increasing inflammation and oxidative damage.

NO forms complexes with transitional metal ions, including those regularly found in metalloproteins. The main trap for no is oxyhemoglobin (oxygen loaded form of hemoglobin) , which binds to NO faster then oxygen. The reaction produces methaemoglobin other NO sensitive metalloproteins are NOS, Cytochrome P450, Ferritin, Ceruloplasmin, mitochondrial respiratory chain. NOS is discussed later, Cytochrome P450 is a very important for detoxing the body. Ferritin helps regulate iron homeostasis. Ceruloplasmin is a copper-carrying protein that is involved in iron metabolism. Mitochondrial respiratory chain is involved in cellular energy.

As NO rises it oxidizes hemoglobin. In healthy individuals about 1% of total hemoglobin has been oxidized mainly by NO. Excess oxidative stress causes excess NO. which can make methemoglobin higher. Methemoglobin contains Fe3 which cannot bind to oxygen. Curcumine and Lactoferrin reduces Fe3 levels in the body. Curcumin can make you anemic if taken for too long because it can also chelate the good iron from the body. Excess methemoglobin is called acquired methemoglobinemia. This can cause skin discoloration, shortness of breath, lethargy, headache, dizzyness, brain fog. Methylene blue helps with this because it is caused by sepsis but those who are G6PD deficient cannot take methylene blue it could kill them.

Some causes of high NO levels.

Prolonged or frequent immune system activation. Which is common in those with CFS, MS, and Fibromyalgia. The most common cause is viral infection. But any number of infections can cause this especially mycoplasma. So to reduce peroxynitrite levels it is important to reduce the viral load on the body, calm the immune system and reduce inflammation.

Inflammation and pro-inflammatory cytokines.

Effects of low NO levels

Low levels of NO will cause low levels of ATP which means the cells would have less energy. This also disables autophagy preventing recycling of mitochondria.

iNOS

NOS is calcium dependent. iNOS is primarily expressed in macrophages a type of white blood cell of the immune system that engulfs and digest cellular debris, foreign substances, microbes, cancer cells and any other cell that does not the type of proteins specific to healthy cells. They are found in almost all tissues in the body. They are expressed primarily after induction by cytokines(small proteins involved in cell signaling) , especially IFN-Y and lippopolysaccharide (endotoxins) . Lippopolysaccharide is abbreviated LPS. Because iNOS contributes to inflammation and destroys parasites and infections it is a major contributor in septic shock. Excessive iNOS can lead to vascular permeability.

Reactive oxygen species works together with reactive nitrogen species to damage cells. Reactive oxygen species produces hydrogen peroxide which can be very damaging to the body. Reactive nitrogen produces peroxynitrite which is also very damaging to the body. Normally the body can neutralize them but when under excess oxidative stress from emotional stress, physical stress, infection, toxins or from nutritional deficiencies the body cannot neutralize and detox the reactive nitrogen and reactive oxygen species. It is a cycle that can be difficult to break. The inflammation that is caused prevents the body from being able to detox and also the metabolic issues it causes puts an even heavier burden on the body because it produces toxins adding to the burden. This is why it is very important to address the nutrient deficiencies caused by illness or toxins and to reduce inflammation.

eNOS

Endothelial NOS (eNOS) is primarily responsible for the generation of NO in vascular endothelium. Endothelium is a monolayer of cells lining the interior surface of blood vessels. No produced by eNOS in the vascular endothelium plays a crucial role in regulating vascular tone, cellular proliferation (process that results in an increase in the number of cells), leukocyte adhesion (white blood cell), and platelet aggregation. eNOS is dependent on calcium and synthesizes NO from L-arginine and oxygen which binds to the heme group of eNOS. Heme is the part of red blood cells that contain the iron which is needed to transport oxygen. The binding of Tetrohydrobiopteran (BH4) is essential for eNOS to generate NO. In the abscense of BH4 which many toxins like glyphosate, mercury and endotoxins can cause eNOS shifts from a dimeric to a monomeric form, thus becoming uncoupled. This causes a production of superoxide anion by eNOS instead of NO. It is a highly reactive free radical that damages the cardiovascular system. This also causes phenylketonuria, ammonia build up in the body because phenylalanine can no longer be recycled. Eating things high in phenylalanine like meat or potatoes will increase the ammonia levels making a person suffering from this sicker, their urine will get dark and smell and when very bad their body odor will be strong.

eNOS causes a reduction in Cationic Amino Acid Transporter 2 (Cat2) which mediates the L-arginine transport needed for raised NO production.

When functioning properly eNOS prevents hardening of the arteries and damage of the blood vessles. It has anti-artheriosclerotic effects. Oxidative stress can cause it to become uncoupled causing many health problems because this also increase reactive oxygen species. This is the one that will cause issues throughout the body because many metabolic pathways will be effected. There are natural ACE inhibitors that will reduce the damage when this happens. Remember the goal is homeostasis. Once the issues that have caused it’s uncoupling have been addressed focus on healing. To continue to take allopathic or natural things to treat symptoms keeps you on a hamster wheel because you have to address the cause. Treating the symptoms will not resolve the problem it will only reduce the symptoms. Enos is very important to the healing of soft tissue throughout the body so it is very important for all pathways to be functioning. Through indirect processes fluoroquinolones also inhibit BH4 and interfere with eNOs. BH4 is involved in the production of serotonin, and L-Tyrosine so inhibition or uncoupling can have dramatic effects on our brains.

Neuronal NOS

Neuronal NOS which used to be known as NOS1 is constitutively(always active) expressed in the central(brain and spinal cord) and peripheral (nerves throughout the rest of the body) neurons and some other cell types.

nNOS functions include synaptic plasticity in the Central Nervous System, central regulation of blood, and vasodilation via nitrergic nerves.

Peroxynitrite

Peroxynitrite is formed when NO reacts with superoxide (O2-) which it readily combines with. The higher the levels of NO present the great the risk of it reacting with super oxide to form peroxynitrite. Peroxynitrite can cause oxidation to hemoglobin causing anemia.

When peroxynitrite is formed it depletes the bioactivity of NO which effect the bodies ability to regulate blood pressure, platelet activation, and vascular cell signaling. This can result in high blood pressure, and hardening of the arteries. When NOS enzymes have limited L-arganine or BH4 they my produce superoxide instead of NO. The can be transformed to peroxynitrite. BH4 reacts with peroxynitrite and is oxidized to biopterin. BH4 is also oxidized by neopterin which is an indication of an immune response. This causes inflammation which in turn can stimulate more peroxynitrite synthesis.

Peroxynitrite can react with other components of the cell including lipids(fats), thiols(organosulfur compounds) , amino acid residues(an amino acid contained within a peptide or protein) , DNA bases (adenine, cytosine, guanine,thymine) , and antioxidants.

Peroxynitrite can react with other molecules to form additional types of RNS including nitrogen dioxide (N2O2) as will as other chemically reactive free radicals which include peroxynitrous acid, hydroxyl radical, carbon dioxide, carbanate radical and dinitrogentrioxide.

Peroxynitrite can react directly with proteins that contain transition metal centers. Therefore it can modify proteins such as hemoglobin, myoglobin, and cytochrom C by oxidising heme into it’s corresponding ferrous forms. Two of the most common reactions is cystein oxidation and tyrosine nitration. These reactions affect protein structure and function so have the potential to cause changes in the catalytic activity of enzymes, altered skeletal organization and impaired cell signal transduction. So it can hinder the bodies ability to heal and examples of illnesses caused by changes in the catalytic activities of enzymes are illnesses such as porphyria and phenylketonuria. Also with the cells ability to communicate impaired all heck can break loose.

Both NO and peroxynitrite can oxidize the iron-sulfur protein based enzymes in the Krebs cycle (citric acid cycle). The iron-sulfur protein is known as Aconitase. Krebs cycle is involved in producing cellular energy. It is the metabolic pathway that connects carbohydrate, fat and protein metabolism. So problems with this pathway would have dramatic effects throughout the body. So we can see the importance of reducing peroxynitrite levels.

No reacts with nitrogen dioxide (NO2) presumably instead of superoxide to form Dinitrogen Trioxide (NO3) , which is a type of reactive nitrogen species. All nitrogen oxides are good oxidizing agents. This cause excess Cyclic GMP, vascular collapse and septic shock, s-nitrothiol formation on proteins (thionitrites).

Now you should be able to see why iNOS has been implicated in inflammatory bowel disorders.

GTP cyclohydrolase increases BH4, folate is needed to produce it. Do not take folic acid it is man made and can build up in the body causing health problems.

Vitamin C the real vitamin C not man made, Vitamin E and Folate not to be mistaken for Folic Acid which is man made and can build up in the body damaging the NMDA receptor and increasing the risk for cancer. These all scavenge peroxynitrite.

Hydroxycolbamin scavenges peroxynitrite

COX2 inhibitors reduce peroxynitrite. In my list of supplements I listed some things that will inhibit COX.

Getting rid of infection and reducing inflammation reduces peroxynitrite.

Reducing toxins in the body especially glyphosate and heavy metals reduces peroxynitrite.

Ellagic Acid reduces peroxynitrite.

https://www.sciencedirect.com/science/article/pii/S0308814608006195

How Nitric Oxide Species are produced.

https://www.sciencedirect.com/science/article/pii/S0005272899000286

Disregulation of NO can cause many health problems from diabetes to cancer.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345541/

Though I do not agree with statin use because it does more damage to the body then oxidative stress does, this article has a good summary of Nitric Oxide production and the enzymes that regulate it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345541/

iNos has been implicated in inflammatory bowel disease.

https://gut.bmj.com/content/45/2/199

Inflammation and infection are known causes of hardening of the arteries. The blood vessels start to leak and the body uses calcium and cholesterol to seal the leaks resulting in hardening of the artieries. INOS causes leakage in blood vessels in response to inflammation and infection. This is why it is very important to address the infection and inflammation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572034/

Excess iNOS production can cause anemia.

http://jultika.oulu.fi/Record/isbn951-42-6851-2

eNOS issues have been linked to cardiovascular disease, erectile dysfunction, hypertension, diabetes, and obesity.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345541/

This is cause by oxidative stress .

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174401/

Toxins and infection can lead to excess NMDA receptor activation which can lead to nitrosative stress.

https://www.researchgate.net/profile/Zezong_Gu2/publication/42441952_Redox_Reactions_Induced_by_Nitrosative_Stress_Mediate_Protein_Misfolding_and_Mitochondrial_Dysfunction_in_Neurodegenerative_Diseases/links/575a2c2e08ae9a9c954f2c86/Redox-Reactions-Induced-by-Nitrosative-Stress-Mediate-Protein-Misfolding-and-Mitochondrial-Dysfunction-in-Neurodegenerative-Diseases.pdf?origin=publication_detail

Epselen can scavenge peroxynititrite but has not been approved for usage for anything but mental disorders.

https://www.sciencedirect.com/science/article/pii/S1054358908609862

Thymoquinone reduces oxidative stress which damages the brain.

https://www.ncbi.nlm.nih.gov/pubmed/28655600

https://www.ncbi.nlm.nih.gov/pubmed/24814387

Baicalein found in sculletaria and plantain herb protects from peroxynitrite damage.

https://www.ncbi.nlm.nih.gov/pubmed/27518088

Arugula another super food.

 

 

arugulaEruca Sativa

This is not medical advice and should not be taken as such. This is for informational and educational purposes. If in doubt don’t, know a plant before you use it.

I found out about this plant by accident. I strange weed started growing in my garden. I posted it in a plant ID group on Facebook and they identified it as Arugula. I tasted it and it had a pleasant taste. Not only that I have Lyme and was having a bad day, after eating it I felt better so decided to find out more about it. I eat it in salads and on pizza but I have heard that it taste good added to dishes you would add oregano to like spaghetti.

https://www.nutrition-and-you.com/arugula.html

https://draxe.com/arugula-salad/

It would help those who have myocarditis or thrombosis it prevents blood clotting. It is probably why it made me feel better because I have Lyme carditis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277002/

It helps with neurological issues and would help with autoimmunity because it restores function of IL-10 which Lyme and HIV inhibit.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928599/

https://www.ncbi.nlm.nih.gov/pubmed/25837274

Arugula helps prevent cancer.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442471/

https://www.sciencedirect.com/science/article/pii/S0367326X11000657?via%3Dihub

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065051/

http://journal.waocp.org/?sid=Entrez:PubMed&id=pmid:26745094&key=2015.16.18.8411

High in antioxidants so it improves skin barrier function.

https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.5138

It contains Isorhamnetin which is also found in onions and other spices. It is renoprotective.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840710/

Phytochemicals

https://pubs.acs.org/doi/abs/10.1021/jf052756t

https://www.ncbi.nlm.nih.gov/pubmed/17590871

https://www.ncbi.nlm.nih.gov/pubmed/27816826

https://www.ncbi.nlm.nih.gov/pubmed/22369966

It chelates the bad iron from the body and reduces reactive oxygen species.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701420/

It inhibits urease which would help with gastric ulcers. It would also help lower ammonia levels in the body.

http://journals.sagepub.com/doi/abs/10.1177/2156587214527452?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed&

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675085/

Reduces Quinone which would help with sepsis, detox issues, a leaky blood brain barrier and hormone issues.

https://www.ncbi.nlm.nih.gov/pubmed/27523193

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312139/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241708/

Would help protect from vaccine injury and other toxins. Protects the thyroid.

https://www.ncbi.nlm.nih.gov/pubmed/17207565

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153205/

https://link.springer.com/article/10.1007%2Fs11356-017-8671-8

http://journal.waocp.org/?sid=Entrez:PubMed&id=pmid:26320454&key=2015.16.14.5801

https://www.ncbi.nlm.nih.gov/pubmed/28913779

It is high in Erucin

https://www.ncbi.nlm.nih.gov/pubmed/27087163

Helps with diabetes.

https://www.karger.com/Article/Abstract/12829

https://www.tandfonline.com/doi/full/10.1080/13880209.2017.1280687

Reduces inflammation because it is high in isothiocyanites.

https://www.ncbi.nlm.nih.gov/pubmed/22453842

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037733/

Skullcap

Scutellaria

This is not medical advice and should not be taken as such , I am posting this for information and educational purposes only. If in doubt don’t please know your plants before using them.

There are many plants that are poisonous that get mistaken for Scutellaria and are sometimes contaminants in supplements containing Skullcap. Two of the most common that can be mistaken for Skullcap that are poisonous are Downy Skullcap (scutellaria icana) and Germander which is in the Teucrium family.

The ones with the most health benefits in the order of effectiveness are Sculletaria Racemosa, Sculletaria Biacalensis, and the one with the best sedative effects is Sculletaria Lateriflore.

They contain biacalein which I have seen miss spelled as biacalin in some studies. It has amazing healing abilities. S Racemosa has the highest levels of biacelain. It has been shown to be very effective against cancer with little side effects. One of the problems I had with Skullcap was that it healed my nerves and improved my blood circulations so fast that all heck broke loose. The best way I can describe it is when you sleep on your arm and it goes to sleep. As the blood flow returns you experience muscle spasms and major tingling. That happened to me for about three days when I started taking it and then I started to feel much much better. I was surprised at how fast it was healing me. I used Sculletaria Racemosa.

https://draxe.com/skullcap/

http://www.herbslist.net/skullcap.html

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678518/

Biacalein has been shown to be effective against liver fibrosis and correct metabolic disorders.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678518/

Skullcap helps with asthma and COPD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5971322/

It has antibacterial and anti inflammatory effects which helps prevent periodontal disease.

https://www.karger.com/Article/Abstract/92853

Effective against various types of cancer.

https://www.spandidos-publications.com/10.3892/mmr.2018.9036

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929448/

https://www.ncbi.nlm.nih.gov/pubmed/29797601

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688794/

https://www.worldscientific.com/doi/abs/10.1142/S0192415X18500027?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed

This would also help interstitial cystitis because this is something cancer patients and those with interstitial cystitis have in common.

https://www.ncbi.nlm.nih.gov/pubmed/29697746

Reduces artherosclerosis by reducing oxidative stress.

https://www.ncbi.nlm.nih.gov/pubmed/29793330

https://www.ncbi.nlm.nih.gov/pubmed/29495284

Reduces inflammation and the way it does it would be very beneficial for those with interstitial cystitis.

https://www.ncbi.nlm.nih.gov/pubmed/29331857

Reduces hypertension

https://www.worldscientific.com/doi/abs/10.1142/S0192415X18500404?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543745/

Improves chances of having a successful pregnancy.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963314/

Helps with autoimmune disorders.

https://www.ncbi.nlm.nih.gov/pubmed/29656117

Protects the brain and nerves and stimulates healing.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758355/

https://www.ncbi.nlm.nih.gov/pubmed/21718777

https://www.jstage.jst.go.jp/article/bpb/41/4/41_b17-00768/_article

Helps with NAFLD, fatty liver disease.

https://www.ncbi.nlm.nih.gov/pubmed/29542003

https://www.ncbi.nlm.nih.gov/pubmed/29158052

https://www.ncbi.nlm.nih.gov/pubmed/29031535

Helps fight the flu.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869510/

http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=5567&category_id=145&option=com_virtuemart&vmcchk=1&Itemid=1

Prevents heart failure.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783530/

https://www.ncbi.nlm.nih.gov/pubmed/29047162

https://www.spandidos-publications.com/mmr/16/6/9251

Reduces bone inflammation.

https://www.ncbi.nlm.nih.gov/pubmed/29253124

Helps heal leaky gut.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707656/

Helps with diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/29028535

The list goes on and on as to the benefits of Skullcap.

Wild Violet

Viola

This is not medical advice and should not be taken as such. It is for information and educational purposes. If in doubt don’t make sure you know your plant before you use them.

Their are many species of wild violet but their nutrients and phytochemistry is pretty much the same.

Viola Biflora, Viola Canina, Viola, V. Labradorica, V. Odorata, V. Rostrata, and V. Sororia are the ones I am familiar with. They all taste the same to me. I love them it is one of my favorite wild edibles. I could eat wild violets daily. They have similar nutrients as dandelion only higher levels of them.

http://www.ediblewildfood.com/wild-violet.aspx

https://thesurvivalmom.com/enjoy-wild-violets/

The viola species have hepaprotective properties.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217637/

They reduce inflammation and an over active immune system.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918579/

Reduces coughing

https://www.ncbi.nlm.nih.gov/pubmed/25954025

Phytochemicals that are good for the heart and oxidative stress.

https://www.ncbi.nlm.nih.gov/pubmed/23035206

Reduces oxidative stress.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967839/

https://www.ncbi.nlm.nih.gov/pubmed/26751970

Is nueroprotective.

https://www.ncbi.nlm.nih.gov/pubmed/27516984

Anti inflammatory.

https://www.ncbi.nlm.nih.gov/pubmed/17983197

Fights cancer

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163403/

Fight bacterial infections.

https://www.ncbi.nlm.nih.gov/pubmed/20558471

Reduces histamines

http://www.thepab.org/files/2017/March-2017/PAB-MS-160199.pdf

https://www.sciencedirect.com/science/article/pii/S0378874113005941

Is high in mucilage which heals the gut. It is so high that when I make tinctures they come out like a gel.

https://thenaturopathicherbalist.com/herbs/v-z/viola-tricolor/