Feel bloated, flatulence smell like rotten eggs?

This is not medical advice, I am posting this for educational and informational purposes.

Boating, stinky flatulence that smell like rotten eggs, abdominal pain, constipation or diarrhea, Bile acid refux, headache, fatigue, muscle pain?

If we have to many Hydrogen Sulfate producing bacteria it can negatively impact our health. This occurs if we eat GMOs which are high in glyphosate and glufonisate or from taking antibiotics for too long. H2S inhibits butyrate oxidation in colonic epithelial cells which causes many health problems even psychosis. This also compromises the intestinal barrier function which causes an energy deficit.

Bismuth blocks H2S production ,Lactobacillus Plantarum and Saccharomyces Cerevisiae reduces Desulfovibrio , and other producers of H2S but there are others that produce it. Glycomacropeptide found in whey protein reduces Desulfovibrio bacteria. Lactoferrin and lactulose have been shown to reduce sulfur digesting bacteria. Galacto-oligosaccharide has been found to increase the good microbes that reduce the sulfur digesting and methane producing bacteria. Fiber also helps reduce sulfur digesting bacteria.

High H2S causes increased inflammation, increased Reactive Oxygen Species, and increase neutrophils in order to convert H2S to thiosulfate. If thiosulfate levels get too high in the blood it can cause a type of anemia called Heinz Body anemia. If a person is G6PD deficient this will make their symptoms much worse. Low thiosulfate levels in the urine could indicate low or inhibited Thiolmethyltransferase. High thiosulfate in the blood can also be caused by excess garlic consumption.

There are urine test for thiosulfate. High levels can indicate high H2S producing bacteria in the gut or it can indicate a deficiency in Thiolmethyltransferase. This can lead to CoQ10 deficiency and NADPH deficiency. This can also lead to inhibited sulfide oxidation which can impair fatty acid oxidation. This also causes glutathione to become depleted. You can also test the urine for H2S.

This can effect each differently depending on the level of H2S. They can either become constipated or get diarrhea. It can result in inflammatory bowel, pouchitis, halitosis, fatty acid deficiency from inhibited fatty acid oxidation and malabsorption. Lower H2S stimulates intestinal contraction and higher levels causes relaxation of the intestines.

High sulfur foods and meat increase H2S levels if the sulfur digesting gut microbiota are high. Most fats can also increase H2S and medium chain fatty acids are usually the best to consume when there are high sulfur digesting bacteria levels. Many of our processed foods contain sulfur as a preservative.

In a lactulose test if the levels of methane and hydrogen are not high then it is most likely dysbiosis caused by high sulfur digesting bacteria levels.

H2S cysteine activates GLUT increasing the transport of glucose into the cell. The excess hydrogen sulfide in the body will cause a person to develop sulfur intolerance. High sulfur foods will cause a reaction or they will become ill.

Polyphenols reduce the H2S producing bacteria. Wine and green tea in moderation can reduce the H2S producing bacteria.

The bacteria that can be found in the stool that are sulfur digesting and produce high levels of H2S are Desulfovibrio, Streptococcus, Enterococcus, and Prevotella.

Often times when a person has dysbiosis they will tell them to avoid starch but resistant starch reduces the H2S producing microbiota. Butyrate found in butter helps reduce the effects of high H2S. We can increase our Butyrate by taking a butyrate producing probiotic and making sure they get the starches and sugars they need.

High H2S levels increases Trimethylsulfonium in urine. High trimethylsulfonium levels can effect indolethylamine-N-methyl-transferease enzymes which is needed for the methylation of thiols. When this is effected It can effect hormones throughout the body. Glyphosate uses a sulfonium salt which could increase the negative effects to add gasoline to the fire glyphosate kills the microbiota that help keep sulfur digesting bacteria levels down.

H2S inhibits nNOS which causes nitric oxide production to become inhibited. This also increase NADPH levels and decreases NADH levels. Increasing BH4 counters the effects of H2S. Leafy greens and beet root increases nitric oxide which will help to increase BH4. Working on improving mitochondrial respiration will help to restore energy production in the mitochondria. Inhibited respiration in the mitochondria causes the high NADPH levels. High NADPH increases oxidative stress so a person may need to increase super oxide dismutase to help reduce the oxidative stress.

Sulfation and high sulfides.

This is not medical advice I am posting this for educational and informational purposes.

Written by Lee Stevenson, sorry I am a lousy editor.

stock-photo-sulfur-or-sulfur-on-old-wood-background-698157433

Sulfation is vital for many processes throughout the body. If sulfation is inhibited or faulty we can develop intolerances to high sulfur foods and even meat. It will also affect the bodies ability to heal. It can cause high histamine, ammonia, hydrogen peroxide and sulfite levels which can cause damage throughout the body. The brain cannot function properly without sulfur. Almost every cell in the body relies on sulfation. There are many things that affect sulfation vaccine injury, toxins especially those found in GMOs , and agricultural chemicals used on our foods. Glyphosate is one of the biggest causes of siltation issues. Those with tick born illness often suffer from this.

Symptoms of high sulfites and some possible causes. Nutrients that help reduce them. When we have sulfation issues it can cause high oxalates. I have posted on oxalates.

http://www.beatcfsandfms.org/html/Sulfides.html

https://mthfrsupport.com/2016/02/impacts-to-our-snps-via-foodtoxins-and-the-resulting-domino-effect-on-their-genetic-expression/

About sulfur metabolism

https://metabolichealing.com/cbs-mutations-regulations-new-observations-insights/

Molybdenum is a key nutrient if we are deficient our bodies cannot convert sulfites to sulfates. This is a nutrient that you should not take high levels of. Once you reach homeostasis you should back off and pulse taking it to maintain homeostasis. To much can have adverse effects on the body.

https://www.nature.com/articles/s41598-018-22751-6

Sulfation is involved in the glucuronidation process. If it is inhibited your ability to detox environmental toxins becomes inhibited. You will develop many sensitivities especially to odors and fumes. It also makes you more sensitive to mold and mold illness and fungal infections.

http://www.newtreatments.org/fromweb/sulfur.html

http://drsircus.com/cancer/cancer-sulfur-garlic-glutathione

https://www.ncbi.nlm.nih.gov/pubmed/3081005

Mercury is still used in some vaccinations especially the flu shot. It has a negative impact on sulfation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774468

Until issues are corrected it may be necessary to temporarily go on a low sulfur diet.

http://drjockers.com/cbs-mutation-low-sulfur-diet

Sulfation issues are a biomarker in autism.

https://www.sciencedaily.com/releases/2017/03/170316141101.htm

https://www.blants.com.au/autism.htmlhtml

One of the main causes of sulfation issues is glyphosate so it is very important to detox it.

https://liveto110.com/166-glyphosate-herbicide-and-how-to-detox-it-with-dr-stephanie-seneff

Sulfation issues cause autism.

http://autismcoach.com/glyphosate-folic-acid-oxalic-acid-vaccines-and-tylenol-wreak-metabolic-havoc-together/

It is very important to restore detox functions.

http://www.ei-resource.org/easyblog/entry/foods-and-supplements-to-balance-phase-1-and-phase-2-liver-detoxification

https://biofoundations.org/how-to-detoxify-your-body-from-glyphosate-exposure

High sulfite sometimes referred to as sulfide levels have been linked to autism. The good sulfur is sulfate. Sulfite has been oxidized and can be a sign of infection, inflammation, high toxin levels or metabolic issues caused by nutrient deficiencies. It could also indicate gut dysbiosis which cause high sulfite and hydroxy radicals.

http://www.learningtarget.com/nosulfites/

Those who have high hydroxy radical levels and high sulfite levels have been found to be deficient in Bifidobacterium Infantis.

https://www.sciencedirect.com/science/article/pii/S2352340918306334?via%3Dihub

High sulfite levels cause mast cell degranulation which can result in high histamine.

https://www.annallergy.org/article/S1081-1206(10)63549-1/pdf

https://genomeinterpretation.org/content/CBS

Glyphosate causes molybdenum cofactor deficiency which inhibits sulfite oxidase, xanthing oxidase, aldehyde oxidase, and Mitochondrial amidoxime-reducing component. Sulfite oxidase catalyzes the oxidation of sulfite to sulfate, xanthing oxidase converts xanthine to uric acid preventing hypoxanthine from forming which would cause deamimation of adenine, mARC is involved in fat metabolism, if inhibited we can develop high triglyceride levels. So you can see how the high sulfites can really effect the body when glyphosate is involved.

https://www.cityofberkeley.info/uploadedFiles/Health_Human_Services/Commissions/Commission_for_Community_Health/Glyphosate,%20pathways%20to%20modern%20diseases%20II_%20Celiac%20sprue%20and%20gluten%20intolera.pdf

https://www.scirp.org/journal/PaperInformation.aspx?PaperID=53106

Tungstate has been shown to help with dysbiosis.

https://www.nature.com/articles/nature25172

Sulfur regulates our cardiovascular system, any disruptions will cause serious health issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709694/

Foods high in sulfur.

https://www.livingnetwork.co.za/chelationnetwork/food/high-sulfur-sulphur-food-list/

We want to correct our metabolic issues because we cannot keep avoiding sulfur, it’s deficiency results in serous illness.

https://www.westonaprice.org/health-topics/abcs-of-nutrition/sulfur-deficiency/

Sulfur protects our lungs from injury.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011328/

It is also involved in remodeling of our collagen so you can imagine what happens when we are deficient or the metabolism of sulfur has been dysrupted.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725894/

Cholesterol and sulfur are some of the most important nutrients to good health.

https://www.ihealthtube.com/video/will-forever-change-how-you-view-cholesterol-and-heart-health

This is why it is important that we get selenium. Mercury found in some vaccinations and in the environment binds to sulfur. Selenium protects us from mercury toxicity.

https://www.tandfonline.com/doi/abs/10.1080/15563650.2017.1400555?journalCode=ictx20

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433557/

Sulfite toxicity causes ALS and glutamate toxicity. So it can cause anxiety, severe headaches and many other health issues.

https://www.ncbi.nlm.nih.gov/pubmed/18973429

Aluminum in vaccinations can cause food allergies which will interfere or change sulfur metabolism.

https://www.jacionline.org/article/S0091-6749(15)02364-7/pdf

Epsom salt baths help us get the right kind of sulfur. If we go into the sun afterwards for a short period of time it will also detox glyphosate and carcinogenic estrogen.

https://drcarolyndean.com/2012/12/magnesium-baths/

Leaky gut starts a vicious cycle it lets oxalates into our blood stream which causes problems with sulfur metabolism. This in turn produces more oxalates which prevent the gut from healing. I found high mucilage foods and bismuth helped heal my gut so I could break the cycle.

http://redmountainclinic.com/the-down-side-to-high-oxalates-problems-with-sulfate-b6-gut-and-methylation/

http://bioindividualnutrition.com/oxalates-their-influence-on-chronic-disease/

Magnesium sulfate (epsom salt) also helps detox organophosphates.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470074/

This is a message board with discussion on how to address many metabolic issues. Very good information here.

https://forums.phoenixrising.me/index.php?forums/genetic-testing-and-snps.12/

Alkalosis and Acidosis also effect sulfation or can be cause by sulfuation issues , I have posted on those.

Infection and toxins can interfere with BH4. This can cause many health problems and has also been linked to autism. Oxidative stress and inflammation can also inhibit it.

https://autismmasterycourse.com/wp-content/uploads/2016/08/Neurochemical-Imbalances-and-Autism-Tetrahydrobiopterin-Metabolism-and-Quinolinic-Acid-Toxicity.pdf-8-15-16.pdf

https://www.medicinenet.com/tetrahydrobiopterin_deficiency/article.htm

Ignore that it is a genetic issue we know that this is proving to be untrue.

http://www.diseaseinfosearch.org/Tetrahydrobiopterin+deficiency/7038

https://www.selfhacked.com/blog/tetrahydrobiopterin-bh4-role-body-buy/

http://www.beyondmthfr.com/mthfr-depression-folate-bh4-connection/

How to increase BH4

https://biochemicals.com/news/how-to-naturally-raise-tetrahydrobiopterin-bh4

If you do not address the sulfite issue it can lead to porphyria which comes with many other illnesses. Phenylketonuria which means you get ill if you eat meat or things high in Phenylalanine like potatoes. Pyrrole issues which means you will get ill from fats and not be able to properly absorb them. Most will get indigestion and have gall bladder issues if they have pyrrole issues. If you have either of those read my pophyria post.

Symptoms of high sulfites and some possible causes. Nutrients that help reduce them.

http://www.beatcfsandfms.org/html/Sulfides.html

About sulfur metabolism

https://metabolichealing.com/cbs-mutations-regulations-new-observations-insights/

Molybdenum is a key nutrient if we are deficient our bodies cannot convert sulfites to sulfates. This is a nutrient that you should not take high levels of. Once you reach homeostasis you should back off and pulse taking it to maintain homeostasis. To much can have adverse effects on the body.

https://www.nature.com/articles/s41598-018-22751-6

Molybdenum is important for many of the detox enzymes.

http://lpi.oregonstate.edu/mic/minerals/molybdenum

Sulfation is involved in the glucuronidation process. If it is inhibited your ability to detox environmental toxins becomes inhibited. You will develop many sensitivities especially to odors and fumes. It also makes you more sensitive to mold and mold illness and fungal infections.

http://www.newtreatments.org/fromweb/sulfur.html

http://drsircus.com/cancer/cancer-sulfur-garlic-glutathione

https://www.ncbi.nlm.nih.gov/pubmed/3081005

Foods that increase UDP-glucuronosyltransferase.

http://dmd.aspetjournals.org/content/30/5/564

https://www.heart-health-guide.com/apigenin.html

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874462/

https://www.selfhacked.com/blog/apigenin-top-11-science-based-health-benefits-apigenin/

Luteiolin is good at increasing UDP-glucuronosyltransferase.

http://secretsofnaturalhealing.blogspot.com/2010/12/luteolin-rich-foods-shown-to-reduce.html

https://www.selfhacked.com/blog/top-11-science-based-health-benefits-luteolin/

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166239

Diosmetin is found in the white parts of citris fruit and dates.

https://pubs.acs.org/doi/abs/10.1021/jf502359x?src=recsys&journalCode=jafcau

https://www.researchgate.net/publication/228115816_Bioactivity_of_Diosmetin_Glycosides_Isolated_from_the_Epicarp_of_Date_Fruits_Phoenix_dactylifera_on_the_Biochemical_Profile_of_Alloxan_Diabetic_Male_Rats

Mercury is still used in some vaccinations especially the flu shot. It has a negative impact on sulfation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774468

Until issues are corrected it may be necessary to temporarily go on a low sulfur diet.

http://drjockers.com/cbs-mutation-low-sulfur-diet

Sulfation issues are a biomarker in autism.

https://www.sciencedaily.com/releases/2017/03/170316141101.htm

https://www.blants.com.au/autism.htmlhtml

One of the main causes of sulfation issues is glyphosate so it is very important to detox it.

https://liveto110.com/166-glyphosate-herbicide-and-how-to-detox-it-with-dr-stephanie-seneff

Sulfation issues cause autism.

http://autismcoach.com/glyphosate-folic-acid-oxalic-acid-vaccines-and-tylenol-wreak-metabolic-havoc-together/

It is very important to restore detox functions.

http://www.ei-resource.org/easyblog/entry/foods-and-supplements-to-balance-phase-1-and-phase-2-liver-detoxification

https://biofoundations.org/how-to-detoxify-your-body-from-glyphosate-exposure

We cannot detox if we do not correct sulfation issues.

http://drsircus.com/cancer/cancer-sulfur-garlic-glutathione/

One of the main causes of sulfation issues is glyphosate so it is very important to detox it.

https://liveto110.com/166-glyphosate-herbicide-and-how-to-detox-it-with-dr-stephanie-seneff

It is very important to restore detox functions.

http://www.gilbertssyndrome.com/detoxification.php

https://biofoundations.org/how-to-detoxify-your-body-from-glyphosate-exposure

High sulfite sometimes referred to as sulfide levels have been linked to autism. The good sulfur is sulfate. Sulfite has been oxidized and can be a sign of infection, inflammation, high toxin levels or metabolic issues caused by nutrient deficiencies. It could also indicate gut dysbiosis which cause high sulfite and hydroxy radicals.

http://www.learningtarget.com/nosulfites/

Those who have high hydroxy radical levels and high sulfite levels have been found to be deficient in Bifidobacterium Infantis.

https://www.sciencedirect.com/science/article/pii/S2352340918306334?via%3Dihub

High sulfite levels cause mast cell degranulation which can result in high histamine.

https://www.annallergy.org/article/S1081-1206(10)63549-1/pdf

https://genomeinterpretation.org/content/CBS

Glyphosate causes molybdenum cofactor deficiency which inhibits sulfite oxidase, xanthing oxidase, aldehyde oxidase, and Mitochondrial amidoxime-reducing component. Sulfite oxidase catalyzes the oxidation of sulfite to sulfate, xanthing oxidase converts xanthine to uric acid preventing hypoxanthine from forming which would cause deamimation of adenine, mARC is involved in fat metabolism, if inhibited we can develop high triglyceride levels. So you can see how the high sulfites can really effect the body when glyphosate is involved.

https://www.cityofberkeley.info/uploadedFiles/Health_Human_Services/Commissions/Commission_for_Community_Health/Glyphosate,%20pathways%20to%20modern%20diseases%20II_%20Celiac%20sprue%20and%20gluten%20intolera.pdf

https://www.scirp.org/journal/PaperInformation.aspx?PaperID=53106

Tungstate has been shown to help with dysbiosis.

https://www.nature.com/articles/nature25172

Sulfur regulates our cardiovascular system, any disruptions will cause serious health issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709694/

Foods high in sulfur.

https://www.livingnetwork.co.za/chelationnetwork/food/high-sulfur-sulphur-food-list/

We want to correct our metabolic issues because we cannot keep avoiding sulfur, it’s deficiency results in serous illness.

https://www.westonaprice.org/health-topics/abcs-of-nutrition/sulfur-deficiency/

Sulfur protects our lungs from injury.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011328/

It is also involved in remodeling of our collagen so you can imagine what happens when we are deficient or the metabolism of sulfur has been dysrupted.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725894/

Cholesterol and sulfur are some of the most important nutrients to good health.

https://www.ihealthtube.com/video/will-forever-change-how-you-view-cholesterol-and-heart-health

This is why it is important that we get selenium. Mercury found in some vaccinations and in the environment binds to sulfur. Selenium protects us from mercury toxicity.

https://www.tandfonline.com/doi/abs/10.1080/15563650.2017.1400555?journalCode=ictx20

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433557/

Sulfite toxicity causes ALS and glutamate toxicity. So it can cause anxiety, severe headaches and many other health issues.

https://www.ncbi.nlm.nih.gov/pubmed/18973429

Aluminum in vaccinations can cause food allergies which will interfere or change sulfur metabolism.

https://www.jacionline.org/article/S0091-6749(15)02364-7/pdf

Epsom salt baths help us get the right kind of sulfur. If we go into the sun afterwards for a short period of time it will also detox glyphosate and carcinogenic estrogen.

https://drcarolyndean.com/2012/12/magnesium-baths/

Leaky gut starts a vicious cycle it lets oxalates into our blood stream which causes problems with sulfur metabolism. This in turn produces more oxalates which prevent the gut from healing. I found high mucilage foods and bismuth helped heal my gut so I could break the cycle.

http://redmountainclinic.com/the-down-side-to-high-oxalates-problems-with-sulfate-b6-gut-and-methylation/

http://bioindividualnutrition.com/oxalates-their-influence-on-chronic-disease/

Magnesium sulfate (epsom salt) also helps detox organophosphates.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470074/

This is a message board with discussion on how to address many metabolic issues. Very good information here.

https://forums.phoenixrising.me/index.php?forums/genetic-testing-and-snps.12/

Alkalosis and Acidosis also effect sulfation or can be cause by sulfuation issues , I have posted on those.

Infection and toxins can interfere with BH4. This can cause many health problems and has also been linked to autism. Oxidative stress and inflammation can also inhibit it.

https://autismmasterycourse.com/wp-content/uploads/2016/08/Neurochemical-Imbalances-and-Autism-Tetrahydrobiopterin-Metabolism-and-Quinolinic-Acid-Toxicity.pdf-8-15-16.pdf

https://www.medicinenet.com/tetrahydrobiopterin_deficiency/article.htm

Ignore that it is a genetic issue we know that this is proving to be untrue.

http://www.diseaseinfosearch.org/Tetrahydrobiopterin+deficiency/7038

https://www.selfhacked.com/blog/tetrahydrobiopterin-bh4-role-body-buy/

http://www.beyondmthfr.com/mthfr-depression-folate-bh4-connection/

How to increase BH4

https://biochemicals.com/news/how-to-naturally-raise-tetrahydrobiopterin-bh4

If you do not address the sulfite issue it can lead to porphyria which comes with many other illnesses. Phenylketonuria which means you get ill if you eat meat or things high in Phenylalanine like potatoes. Pyrrole issues which means you will get ill from fats and not be able to properly absorb them. Most will get indigestion and have gall bladder issues if they have pyrrole issues. If you have either of those read my pophyria post.

This is why I stress the importance of homeostasis and not looking at things as I have to cure or get rid of something. We need sulfur to regulate our blood pressure. If we get our levels too low we could develop high blood pressure.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822510/

Sulfur deficiency may lead to obesity. So we really need to focus on restoring the metabolic pathways that need sulfur so our health is not negatively impacted.

https://www.westonaprice.org/health-topics/abcs-of-nutrition/sulfur-deficiency/

Sulfur is needed to regulate the Nrf2 pathway which is the master regulator of the antioxidant system.

https://www.liebertpub.com/doi/abs/10.1089/ars.2012.4944?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

Sulfur is needed for a variety of cellular functions.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845716/

This is why we need to try our best to avoid farm chemicals that are found in and on much of our food. Many of them especially glyphosate can inhibit sulfation.

https://www.researchgate.net/publication/319281616_Can_glyphosate’s_disruption_of_the_gut_microbiome_and_induction_of_sulfate_deficiency_explain_the_epidemic_in_gout_and_associated_diseases_in_the_industrialized_world

Sulfites inhibt Soux when they get to high and this can lead to issues with glutamate. This causes sulfite sensitivities.

http://www.jbc.org/content/279/41/43035.long

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017445/

https://www.chem.uwec.edu/Webpapers2005/mintermm/pages/GDH.html

http://www.readingtarget.com/nosulfites/where.htm

Issues with sulfation can result in Gauchers disease.

https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC1147041&blobtype=pdf

High estrogen levels can cause high sulfites leading to a cycle that is hard to break.

Issues with sulfatase has been linked to many diseases including cancer and lysosomal storage diseases.

https://academic.oup.com/hmg/article/14/21/3203/2355820

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452883/

Melatonin helps regulate sulfatase activity.

https://www.ncbi.nlm.nih.gov/pubmed/26458420

Information on melatonin.

https://lifespa.com/melatonin-rich-foods-will-improve-health/

Sulfotransferase is involved in adipogenesis and energy homeostasis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993609/

http://diabetes.diabetesjournals.org/content/61/6/1353

It also regulates Nrf2 homeostasis. High estrogen activates Nrf2 , which reduces estrogen. When levels reach homeostasis it will shut Nrf2 off. Then when it gets low it will turn Nrf2 on stimulating estrogen production so a working Nrf2 pathway is very important for proper antioxidant function and estrogen homeostasis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505540/

Berries reduce the effects of high estrongen.

https://www.ncbi.nlm.nih.gov/pubmed/18444155.

Herbs that help with estrogen dominance.

https://hormonesbalance.com/articles/7-herbs-manage-estrogen-dominance-pms-breast-lumps-cellulite/

https://sarahjanesandy.com/natural-remedies-for-estrogen-dominance/

https://www.bewell.com/blog/15-ways-to-protect-yourself-from-excess-estrogen/

http://main.poliquingroup.com/ArticlesMultimedia/Articles/Article/801/10_Ways_To_Lower_Estrogen_Toxic_Load_.aspx

SBHG regulates our hormone levels and low levels can cause high estrogen. High estrogen leads to many metabolic issues and sludgy bile flow.

http://healthyhormones.us/shbg-test/

Boron reduces SBHG which reduces estrogen.

https://www.ncbi.nlm.nih.gov/pubmed/30037620

Some herbs reduce it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846366/

Many toxins can effect hormone status leading to aging.

https://www.ncbi.nlm.nih.gov/pubmed/26254889

Ways to lower SHBG to increase testosterone or reduce estrogen.

https://www.anabolicmen.com/how-to-lower-shbg-naturally/

https://healthisking.life/lower-shbg-females/

Low levels of boron increases estrogen and high levels decreases it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712861/

Excess endogenous hydrogen peroxide can decrease estrogen it can lead to bone lose so we must be cautious if we increase our H2O2 levels.

https://academic.oup.com/endo/article/146/2/728/2878298

Hydrogen peroxide is needed for redox signaling high estrogen levels can interfere with it’s proper function.

https://www.sciencedirect.com/science/article/pii/S0891584913000440