Fatty Liver, Cirrohsis, thrombosis and other diseases caused by fibrosis.

 

 

Gray1086-liverThis is not medical advice. I am posting this for educational and informational purposes. It takes time, persistence and research to heal.

Fibrosis can result in excess blood clotting, muscle damage, NAFLD, COPD and many other illness. I have posted on oxidative stress, inflammation and infection. I have also posted on toxins like glyphosate, glufosinate, mercury and detoxing them. All those things can cause fibrosis. Modern medicine looks at the symptoms and not the cause for example when the liver or lungs are failing they view those as the problem but most things like that are from a systemic failure throughout the body caused by many things. If you read my post it is your gut and not your genes you will see many things they blame on genetics can be corrected in the gut. Even thought this post is about NAFLD these things should help with just about any illness caused by fibrosis including thrombosis (blood clotting) because many of them have similar causes.

Ways NAFLD developes

https://www.futuremedicine.com/doi/full/10.2217/pgs-2016-0047

Genes and NAFLD, keep in mind things they thought were genetic and could not be changed they have found can be and people can heal.

http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0050256

Good list of supplements for NAFLD.

https://www.nationalnutrition.ca/HEALTHCONCERNS_fatty_liver_disease.aspx

https://www.atkins.com/how-it-works/library/articles/to-protect-your-liver-take-five

Foods that may help.

https://naturalon.com/fight-fatty-liver-disease-with-these-12-natural-methods/view-all/

Krill Oil and other fats may help with fatty liver.

https://www.omicsonline.org/open-access/oral-intake-of-krill-oil-has-prophylactic-and-potential-therapeutic-effectson-alcoholic-fatty-liver-in-rats-fed-with-highfat-diet-2167-0501-1000189.php?aid=61584

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268598/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930973/

https://www.ncbi.nlm.nih.gov/pubmed/8979168

Pantethine has been shown to reverse fatty liver disease. but excessive use may cause fatty liver.

https://www.ncbi.nlm.nih.gov/pubmed/11425046

https://universityhealthnews.com/daily/heart-health/5-powerful-pantethine-benefits/

Ubiquinol helps reduce fatty liver.

http://healthandscience.eu/index.php?option=com_content&view=article&id=623:supplements-of-q10-may-help-people-with-liver-disease&Itemid=198&lang=en

https://alsearsmd.com/2016/08/non-alcoholic-fatty-liver-disease/

https://articles.mercola.com/sites/articles/archive/2011/06/29/this-form-of-co-q-10-found-far-superior-to-one-typically-being-sold.aspx

Low P5P can cause fatty liver disease.

https://www.gastrojournal.org/article/S0016-5085(84)80110-9/pdf

https://paulaowens.com/vitamin-b6-deficiency/

PPC may help with fatty liver.

https://academic.oup.com/jn/article/127/9/1800/4728940

SAM helps with fatty liver.

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1530-0277.2008.00803.x

https://academic.oup.com/ajcn/article/76/5/1183S/4824268

Carnitine helps with fatty liver.

http://care.diabetesjournals.org/content/38/7/1245.long

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209366/

Those with fatty liver have been found to be low in magnesium. This can be cause by oxidative stress, inflammation , toxins and metabolic disorders.

https://www.ncbi.nlm.nih.gov/pubmed/29435319

https://www.nature.com/articles/s41598-017-18076-5

Fruit vinegars help with fatty liver.

https://www.tandfonline.com/doi/full/10.3109/13880209.2015.1031910

http://fattyliverdietreview.com/does-apple-cider-vinegar-help-with-a-fatty-liver/#axzz5OBoTWWyi

Alpha R-lipoic Acid helps with fatty liver.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929137/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976966/

Treatment options for NAFLD.

https://www.wjgnet.com/1007-9327/full/v23/i36/6549.htm

Nattokinase also reduces fibrinogen which would help with COPD and NAFLD.

https://www.sciencedirect.com/science/article/pii/S0271531709000220?via%3Dihub

This is a site with a list of things that can cause NAFLD. Most of these issues I have posted on if you search my blog.

https://mybiohack.com/blog/nafld-nash-cld

Renal function can improve at any stage of illness.

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081835#s4

In some Tenascan-C becomes activated which can lead to fibrosis throughout the body including the liver and lungs.

http://news.feinberg.northwestern.edu/2016/06/mechanism-behind-chronic-fibrosis-discovered/

Illnesses that cause damage to the body from increased inflammation and oxidative stress can cause raised Tenascan-C levels.

https://pdfs.semanticscholar.org/226c/57aec0c9e736f0253a1f8c4e2c31c63d3c6d.pdf

Tenascin-C is high in tissue injury which is why it is important to address the issues that are causing the injury. Whether it is metabolic issues, nutrient deficiencies, toxins , infection or oxidative stress.

https://www.e-sciencecentral.org/upload/molcell/pdf/molcell-34-1-35-5.pdf

Ace inhibitors may help with fatty liver. I have posted on natural ACE inhibitors in my hypertension post.

https://www.ncbi.nlm.nih.gov/pubmed/18239590

https://fg.bmj.com/content/5/4/277

Vitamin E found in things like Olive Oil and Fish Oil helps with fatty liver.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789322/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712166/

Vitamin D deficiency or a number of metabolic disorders or toxins can prevent the body from converting vitamin D to D3. Low levels of D3 can increase Tenascan-C levels. Supplementing with D3 may reduce Tenascan-C levels.

https://www.sciencedirect.com/science/article/pii/S0014579398003482

Alcoholics get cirrhosis of the liver because it depletes the nutrients (cofactors) needed for sulfation and glucuronidation.

https://www.ncbi.nlm.nih.gov/pubmed/3081005

Cholesterol dysregulation and NAFLD.

http://www.cell.com/cell-metabolism/abstract/S1550-4131(12)00144-1#.V3mMaZ8-dsE.facebook

Homocysteine NAFLD

https://www.sciencedirect.com/science/article/pii/S0014579309001860

Betaine, Homocysteine, NAFLD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642650/

Those who have issues with thiols cannot take betaine. I have posted on thiols.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265525/

Estrogen PEMT

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430895/

Estrogen,PEMT and choline deficiency.

https://www.ncbi.nlm.nih.gov/pubmed/21059658

Choline deficiency can lead to NAFLD, there also also metabolic issues that can interfere with the bodies use of choline.

https://www.ncbi.nlm.nih.gov/pubmed/21059658

A deficiency in PEMT enzymes leads to fatty liver.

https://www.news-medical.net/news/20160307/Absence-of-PEMT-enzyme-leads-to-development-of-fatty-liver-disease-and-tumours-in-thin-patients.aspx

The vagus nerve can effect PEMT levels.

https://www.ncbi.nlm.nih.gov/pubmed/25433161

Misaligned vertebrae and vagus nerve.

https://www.atlantotec.com/en/fundamentals/autonomic-nervous-system

Dysregulation of PEMT will result in liver dysfunction from choline deficiency. It is not mentioned in this study but nutrient deficiencies and metabolic issues like inhibited sulfation and issues with thiols can cause this. I have posted on those. Carcinogenic estrogen can build up in the body effecting these receptors. This can be caused by vaccine injury, heavy metals and glyphosate. Under normal health estrogen induces PEMT. PEMT homeostasis is important for preventing fibrosis throughout the body.

http://www.beyondmthfr.com/estrogen-methylation-and-choline-deficiency/

http://www.beyondmthfr.com/mthfr-digestion-methylation-connection-gallbladder-function/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020773/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430895/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601486/

A deficiency in PEMT leads to fatty liver disease.

https://www.news-medical.net/news/20160307/Absence-of-PEMT-enzyme-leads-to-development-of-fatty-liver-disease-and-tumours-in-thin-patients.aspx

http://roosclues.blogspot.com/2017/02/gallbladder-disease-connection-between.html

This is a more in depth article on PEMT.

http://geneticgenie.org/blog/2013/10/21/acetylcholine-deficiency-in-chronic-illness-the-hunt-for-the-missing-egg/

PEMT issues can result in lung dysfunction.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983399/

High levels of certain gut bacteria , and high endotoxin levels can cause PEMT issues. I have posted on gut bacteria and how to reduce the strains mentioned, I think it was in my gut bacteria post. Leaky gut and infection causes high endotoxin levels and I have posted on how to address those.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049827/

https://www.sciencedirect.com/science/article/pii/S2542568418000041

SNAIL1 inhibition can reverse fatty liver caused by PEMT dysfunction.

https://www.spandidos-publications.com/etm/14/5/4231

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020706/

A natural pesticide form the melia toosendan tree inhibits SNAIL1. It is used to get rid of parasites in the body.

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ptr.6132

https://www.sciencedirect.com/science/article/pii/S0367326X14002561

Eucalyptol is a SNAIL1 inhibitor.

http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=22311&path%5B%5D=70602

Insulin resistance caused by inflammation and oxidative stress can lead to NAFLD.

https://www.sciencedirect.com/science/article/pii/S0925443914002579

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265866/

Betaine (TMG) helps with fatty liver.

https://academic.oup.com/ajcn/article/80/3/539/4690529

Antitrypsins defiency can lead to NAFLD. Raw egg whites and Lima beans inhibit trypsin but I do not know if it will help , I could not find research on humans. Though there are studies on mice that show beans that have trypsin inhibitors in them being effective. There are studies showing the trypsin inhibitors in beans fight cancer.

https://www.sciencedirect.com/science/article/pii/S0954611111000515

https://www.sciencedirect.com/science/article/pii/S0271531715002808

https://www.hindawi.com/journals/bmri/2010/219793/

Ursodeoxycholic acid reduces liver fibrosis. Inhibited sulfation can cause a deficiency in ursodeoxycholic acid. It can also cause sulfated ursodeoxycholic acid to build up in the liver causing damage. This can also cause problems in the intestines, resulting in inflammation and even intestinal lesions. There are a number of things that cause liver fibrosis and many of them can be addressed by increasing the gut bacteria that produce ursodeoxycholic acid.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024236/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082879/

http://www.em-consulte.com/en/article/100091

https://www.wisegeek.com/what-is-ursodeoxycholic-acid.htm

I gut bacteria help keep our liver healthy.

https://www.sciencedirect.com/science/article/pii/S2212877816300564

https://www.ncbi.nlm.nih.gov/pubmed/28983453

Our gut bacteria also protect our livers from infection.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097911/

Parental nutrition effects the health of an infants liver.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622747/

Enterococcus Lactis protects the liver from oxidative stress.

https://www.ncbi.nlm.nih.gov/pubmed/21778036

Oligosaccharrides increase the beneficial bacteria that produce ursodeoxycholic acid, this helps with liver fibrosis which has been found to be common in those with SIBO.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812493/

Obeticholic acid reduces liver fibrosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5970222/

Bile acid dysfunction has been connected to many chronic illnesses.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966875/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874546/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535499/

Metabolic issues effect bile acid production which can lead to illness.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954621/

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157427

http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=22803&path%5B%5D=71990

Our gut bacteria regulate our bile acids, bile acid dysfunction can lead to kidney and liver disease.

http://www.mdpi.com/2072-6643/9/10/1124

https://www.nature.com/articles/nrgastro.2018.23

https://www.cell.com/cell-metabolism/pdf/S1550-4131(16)30223-6.pdf

https://www.hindawi.com/journals/grp/2015/398585/

https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-017-0462-7

https://academic.oup.com/ndt/advance-article-abstract/doi/10.1093/ndt/gfy172/5043141#.W1TXZnvKNpQ.facebook

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229528/

Lithium in low doses heals the kidneys in high doses it can damage them.

https://www.physiology.org/doi/abs/10.1152/ajprenal.00145.2016?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed

https://nutritionreview.org/2013/04/lithium-orotate/

Dybiosis can cause poor liver health regardless of our body fat levels.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780381/

Fasting increases HSP70 which helps with NAFLD. I have posted on HSP70

http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0110748

Ginseng may help with liver fibrosis.

https://www.jstage.jst.go.jp/article/bpb/41/4/41_b17-00934/_article

https://www.kgcus.com/blog/benefits-of-ginseng-in-treating-liver-function-problems-and-diseases/

Oligosacharride helps normalize our gut bacteria.

https://www.jstage.jst.go.jp/article/jnsv/63/4/63_269/_article

https://www.physiology.org/doi/pdf/10.1152/ajpgi.00324.2015

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157427

https://www.sciencedirect.com/science/article/pii/S0016508517356986

http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0117851

This study shows the importance of bile acid homeostasis in the prevention of NAFLD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651899/

Nrf2 regulates bile acid homeostasis. I covered Nrf2 in my antioxidant post.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947974/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420438/

https://www.physiology.org/doi/full/10.1152/ajpgi.00322.2010

Trehalose reduces oxidative stress by regulating Nrf2/keap1 pathway and induces autophagy.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730428/

https://www.ncbi.nlm.nih.gov/pubmed/26905426

Choline metabolism and our gut bacteria are connected to liver disease. A sign of metabolic issues that need addressed is gall bladder trouble and indigestion when eating foods high in choline.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601486/

We need to get the correct fats an adequate amounts of cholesterol for bile production. We also must address issues that may cause a loss of cholesterol and fats by oxidation . I have posted on oxidative stress and inflammation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811459/

I have posted on thiols. Cholesterol dysregulation can cause NAFLD.

https://www.cell.com/cell-metabolism/abstract/S1550-4131(12)00144-1#.V3mMaZ8-dsE.facebook

Hemochromatosis can cause liver fibrosis. They claim it is genetic but I have seen studies showing toxins, infection and excess oxidative stress can cause it. Curcumine also reduces iron overload but taking it for too long can cause anemia. Lactoferrin reduces symptoms of iron overload by normalizing levels of iron in the blood though I have not research the safety of it’s use in liver disease.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657669/

This is a list of herbs that helps with hemochromatosis.

https://academic.oup.com/jn/article/143/7/1061/4637651

Liver fibrosis is caused by increased collagen production.

https://www.spandidos-publications.com/mmr/13/5/4335

Porphyria can lead to fatty liver. I have posted on it.

http://europepmc.org/articles/PMC3021615

http://www.porphyriafoundation.com/about-porphyria/types-of-porphyria/PCT

Stringy Stonecrop help with liver fibrosis.

https://www.sciencedirect.com/science/article/pii/S0024320514004135?via%3Dihub

NAD+ may help with fatty liver.

https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.13513

Eleuthero reduces fatty liver.

https://link.springer.com/article/10.1007/BF02974078

Diosmetin found in citrus fruit reduces liver fibrosis.

https://www.ncbi.nlm.nih.gov/pubmed/27101925

Inhibiting USAG1 may help with Alport Syndrome. Proteinuria is part of the problem with Alport Syndrome. If I get a chance I will research the effects of protease on Alport Syndrome.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827946/

Biochanin A which is found in red clover and in the red papery covering of peanuts prevents liver fibrosis.

http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0069276

Relaxin helps reduce lung fibrosis which would help with COPD.

https://www.frontiersin.org/articles/10.3389/fphar.2017.00318/full

Bacteriodes Fragilis reduces liver injury.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5097911/

I found this interesting IDO deficiency causes liver fibrosis. IDO deficiency can be caused by metabolic issues, toxins like mercury, glyphosate and glufosinate. Infection cause high quinolinic acid levels which can cause IDO deficiency. Also toxins from mold can cause IDO deficiency. High IDO levels can cause cancer so this is not something you would want to increase but something you would want to restore homeostasis to.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012673/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415894/

http://chikd.org/journal/view.php?id=10.3339/chikd.2015.19.2.79

https://www.washingtonpost.com/news/to-your-health/wp/2018/03/10/dentists-keep-dying-of-this-deadly-lung-disease-the-cdc-cant-figure-out-why/?utm_term=.c4eac3e7e373

High MMP levels causes fatty liver.

https://www.ncbi.nlm.nih.gov/pubmed/23136827

https://www.ncbi.nlm.nih.gov/pubmed/29856896

This is a list of MMP inhibitors. I find it strange that many of these also fight viruses.

https://www.sciencedirect.com/science/article/pii/B9780444626158000035

http://researchinventy.com/papers/v7i2/B07020410.pdf

Fraxinux Excelsior seed helps reverse fatty liver.

https://www.researchgate.net/publication/276144825_Preventive_Effect_of_a_Fraxinus_Excelsior_L_SeedsFruits_Extract_on_Hepatic_Steatosis_in_Obese_Type_2_Diabetic_Mice

https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-016-1398-0

https://www.omicsonline.org/open-access/preventive-effect-of-a-fraxinus-excelsior-l-seedsfruits-extract-onhepatic-steatosis-in-obese-type-2-diabetic-mice-2155-6156-1000527.pdf

Theraputic targets to help with fibrosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326607/

Those with liver fibrosis have been found to be deficient in Vitamin A.

https://academic.oup.com/ajcn/article/102/1/130/4564323

Other vitamin deficiencies connected to liver fibrosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849418/

Zinc deficiency is common in cirrhosis of the liver.

https://www.ncbi.nlm.nih.gov/pubmed/1505922

Berberine helps with NAFLD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947506/

Metabolic issues, oxidative stress, toxins especially mecury and glyphosate can cause the loss of retinoic acid receptor. I have posted on how to address those things.

https://www.sciencedirect.com/science/article/pii/S1386634605003128?via%3Dihub

Rumex Visicarius can help prevent liver disease.

https://www.ncbi.nlm.nih.gov/pubmed/25702903

Burdock root is hepaprtoective.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355822/

Kudzu has many healing properties. It is hepaprotective.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733283/

Though this is the kidneys I am sure this could happen in the liver also. Infection especially tick born illness can cause antiphospholipid syndrome. Vaccine injury can also cause this. Antiphospholipid syndrome can cause fibrosis in the kidneys.

http://www.scielo.mec.pt/scielo.php?script=sci_abstract&pid=S0872-01692017000300009

Paeony helps reduce symptoms of kidney disease.

https://link.springer.com/article/10.1007%2Fs11255-016-1345-5

Low carbohydrate diet reduces kidney disease in diabetes. I have posted on diabetes. This would be a temporary fix. It is better to address the issues causing it.

https://www.sciencedaily.com/releases/2011/04/110420184429.htm

List of herbs that help cleanse the kidneys.

https://www.top10homeremedies.com/kitchen-ingredients/top-10-super-herbs-to-cleanse-your-kidneys.html

Many medications can cause liver fibrosis especially fluoroquinolones.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654244/

http://www.ajhp.org/content/71/1/37?sso-checked=true

https://pubs.acs.org/doi/abs/10.1021/pr401230s

Murcormycosis is a lung infection and if not addressed it can lead to liver disease and COPD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309303/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828593/

Cristifolin found in Joe Pye helps with liver fibrosis but it contains an alkaloid that can build up in the body so I would not recommend over use.

https://www.thieme-connect.com/DOI/DOI?10.1055/s-2006-957558

How isoflavones protect the liver.

https://www.wjgnet.com/1007-9327/full/v21/i4/1099.htm

Sirt1 activators help reduce NAFLD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555103/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440403/

Inhibited Sirt.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710930/

Silymarin found in milk thistle seed inhibits mTOR which has been found to help with NAFLD.

https://www.ncbi.nlm.nih.gov/pubmed/26186142

Stevia Extract has hepaprotective properties.

https://www.sciencedirect.com/science/article/pii/S1056872712002802

Glyphosate causes liver damage resulting in liver fibrosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3600513/

http://www.organic-systems.org/journal/92/abstracts/Swanson-et-al.html

https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-015-0109-2

https://www.nature.com/articles/srep39328

Cathepsin B causes NAFLD.

http://www.jbc.org/content/early/2017/12/19/jbc.M117.778365.full.pdf

There are natural Cathepsin inhibitors but have not found studies on their effectiveness.

https://www.sciencedirect.com/science/article/pii/B9780444637499000062

https://www.omicsonline.org/open-access/cathepsin-b-inhibitors-for-targeted-cancer-therapy-1948-5956.1000302.php?aid=32883

Japanese Honeysuckle helps with liver fibrosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632443/

Plantain herb is hepaprotective.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861812/

Artichoke is hepaprotective.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879230/

Yarrow protects the renal system and reduces oxidative stress.

yarrow protects the renal system.

https://onlinelibrary.wiley.com/doi/abs/10.1002/ptr.1897

reduces oxidative stress.

https://www.hindawi.com/journals/ecam/2013/893050/

https://www.researchgate.net/publication/317632510_Pharmacognosy_Phytochemistry_and_Pharmacological_Properties_of_Achillea_millefolium_L_A_Review

http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2011/09/WC500115468.pdf

Ginger is hepaprotective and reduces oxidative stress.

https://www.sciencedirect.com/science/article/abs/pii/S0753332218316688

https://www.sciencedirect.com/science/article/abs/pii/S0753332218324168

Hibiscus is in the mallow family. Most plants in the mallow family are hepaprotective.

Hibiscus is hepaprotective.

https://www.sciencedirect.com/science/article/pii/S030881461400692X?via%3Dihub

Rose hip is hepaprotective.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877970/

https://www.ncbi.nlm.nih.gov/pubmed/23880806

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485961/

White malberry helps with NAFLD

https://www.sciencedirect.com/science/article/pii/S0009279717311377?via%3Dihub

https://www.jfda-online.com/article/S1021-9498(17)30196-5/fulltext

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981255/

https://foodandnutritionresearch.net/index.php/fnr/article/view/1289

Sages have many healing abilities. Red Sage helps with liver fibrosis.

Red Sage helps reverse liver fibrosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054956/

Sirt activators help with NAFLD. Resveratrol found in grape seed extract is a sirtian activator.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155167/

Beta Glucan found in mushrooms, whey protein and whole grains help with liver fibrosis.

Beta glucan protects from fibrosis which is found in COPD and NAFLD.

https://www.europeanreview.org/article/8816

Rooibos protects the renal system by reducing oxidative stress.

It also protects the renal system the same way.

https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-14-392

Causes of lipid storage disease.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879869/

Oxidative stress causes renal damage, this is how Tylenol causes liver damage. Corn Silk helps protect the liver from oxidative stress, it is yummy to.

https://www.hindawi.com/journals/ecam/2016/2046298/

miR22 promotes liver fibrosis.

http://www.jbc.org/content/288/51/36202.full

miR22 is modulated by our gut bacteria, our mRNA communicate with our gut microbiome. So if we have undressed health issues then this could be disrupted.

https://ucdavis.pure.elsevier.com/en/publications/butyrate-induces-ros-mediated-apoptosis-by-modulating-mir-22sirt-

https://www.frontiersin.org/articles/10.3389/fmicb.2018.00151/full

Plants that should be avoided because they have alkaloids that can destroy the liver or kidneys.

Plants with poison alkaloids.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983973/

Lipoxin reduces inflammation which should help with NAFLD. I have not had a chance to research how to increase lipoxin.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598198/

I do not like metformin because of the effects of long term use on the body. I am posting this to show that folic acid is toxic to the body and is used to damage the liver of animals in test. It is man made and our bodies make very little of the enzyme needed to break it down. This causes the excess that cannot be broken down to enter the blood stream causing damage throughout the body. Folate which is natrual does not have this effect on the body. They fortify our food with folic acid making it toxic, so those with NAFLD should try to avoid foods containing folic acid.

https://www.ncbi.nlm.nih.gov/pubmed/29380373

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340065/

Glycogen storage disease.

http://themedicalbiochemistrypage.org/vongierkedisease.php

Beta Glucuronidase is bad for NAFLD but helps with lysosomal storage disease.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC294437/

Those with NAFLD can be deficient in B12

https://www.b12-vitamin.com/blood-levels/

Mitochondrial disfunction is common in NAFLD, PQQ improves mitochondrial function.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140972/

Hibiscus is hepaprotective.

https://www.sciencedirect.com/science/article/pii/S030881461400692X?via%3Dihub

Red Sage helps reverse liver fibrosis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054956/

Beta glucan protects from fibrosis which is found in COPD and NAFLD.

https://www.europeanreview.org/article/8816

Reduces blood pressure.

https://academic.oup.com/ajcn/article/104/6/1534/4564684

https://link.springer.com/article/10.1007%2Fs00125-014-3305-x

Rooibos protects the heart by reducing oxidative stress and by reducing inflammation. Rooibos is also an ACE inhibitor.

https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-017-0200-8

https://www.ncbi.nlm.nih.gov/pubmed/22095883

Tenascan-C is needed for heart repair.

https://www.nature.com/articles/srep04051

https://www.frontiersin.org/articles/10.3389/fphys.2014.00283/full

Tenascan-C is high in COPD

https://respiratory-research.biomedcentral.com/articles/10.1186/1465-9921-12-48

Tenascin-C is high in tissue injury which is why it is important to address the issues that are causing the injury. Whether it is metabolic issues, nutrient deficiencies, toxins , infection or oxidative stress. This also causes high oxLDL levels.

https://www.e-sciencecentral.org/upload/molcell/pdf/molcell-34-1-35-5.pdf

Fructose and NAFLD, fruit fructose is different it is processed fructose that causes the problem. Just as processed honey loses it’s health benefits so does processed fructose.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372893/

Insulin/Snail1 issues are involve in macrophagy which shows that NAFLD is a macrophagy issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048127/

Macrophagy issue also cause lipogenesis issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108423/

https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-015-0450-z

Those with NAFLD have glycolysis issues. This indicates macrophagy issues.

https://www.journal-of-hepatology.eu/article/S0168-8278(13)00362-0/pdf?code=jhepat-site

macrophagy issues have been linked to NAFLD.

https://www.hindawi.com/journals/bmri/2014/120179/

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Boneset

 

Eupatorium Perfoliatum

I  have written this for educational purposes. If in doubt don’t, make certain you know your plants. This is not medical advice and should not be taken as such.

There are many varieties of Boneset but this is the one I am familiar with. Eupatorium Perfoliatum is the one that is most common in my area. It is great for fighting the cold and flu. It dramatically reduces the duration of both. It has also been shown to fight cancer. I have used it when I have gotten ill and could not believe how fast it worked the results were surprising.

Boneset has many amazing properties but can be toxic so should only be used when very ill and not for extended periods of times. Also something to keep in mind. The dose makes the poison. If you drink too much water you will flush your electrolytes out and can cause a heart attack. So even though many plants contain alkaloids that can harm the body in high doses or if taken in for extended periods of time they can harm the body. Borage is one such food that contains an alkaloid that can build up in the body and harm it.

http://www.herbaltransitions.com/materiamedica/Eupatorp.htm

Some claim drying the herb destroys the toxic alkaloid.

http://www.rjwhelan.co.nz/herbs%20A-Z/boneset.html

Now to show the benefits if used in moderation.

http://klemow.wilkes.edu/Eupatorium.html

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323186/

It reduces inflammation and will lower cholesterol.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945065/

Has great antiviral properties.

https://www.ncbi.nlm.nih.gov/pubmed/24078828

https://www.sciencedirect.com/science/article/pii/S0378874116302793?via%3Dihub

It has even been shown to be effective against protozoa infection.

https://www.sciencedirect.com/science/article/abs/pii/S0031942211000525