Diabetes, type 1, type 2 and type 3c.

 

This is not medical advice, I am posting this for educational and informational purposes.

Excess Oxidative stress leads to chronic illness there is a test to see if you have excess oxidative stress. If you do not get it resolved you cannot heal. There is a test that can check for excess oxidative stress.

https://www.sciencedirect.com/science/article/pii/S0009898103004534

There are other test that can help identify which areas of the anti-oxidant system are working and which may not be working. This can help identify the sources of high ROS levels or other toxins produced in the body from oxidative stress.

https://drjockers.com/oxidative-stress-test/

One thing we must get rid of is believing that our genes are written.

https://www.telegraph.co.uk/news/science/10369861/Epigenetics-How-to-alter-your-genes.html

Dynamics of B-cell insulin secretion.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324607/

How B Cells are destroyed.

https://www.sciencedirect.com/science/article/pii/S0896841103000398?via%3Dihub

Leptin can help with diabetes. I do not like Yales research it is usually conditionally bias and even flawed but I have seen research to back this one.

https://news.yale.edu/2014/06/15/how-leptin-satiety-hormone-reverses-diabetes

http://www.pnas.org/content/107/11/4813.full

Increasing Leptin sensitivity can reduce body weight.

https://medlicker.com/1038-foods-that-increase-leptin-sensitivity

https://universityhealthnews.com/daily/nutrition/how-to-increase-leptin-sensitivity-5-strategies-for-easier-fat-loss/

https://blog.bulletproof.com/how-to-reset-your-leptin-sensitivity-and-master-your-metabolism/

Role of Pancreas

https://my.clevelandclinic.org/health/diseases/8103-pancreatitis

Type 2 diabetes is insulin resistance.

https://www.diabetes.co.uk/type2-diabetes.html

In type 1 diabetes the body does not produce enough insulin.

http://www.diabetes.org/diabetes-basics/type-1/?referrer=https://www.google.com/

Thyroid issues and Addison’s disease is common in type 1 diabetes which are symptoms of sepsis or endotoxemia.

https://pmj.bmj.com/content/75/886/467.short

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137618

https://www.metabolismjournal.com/article/S0026-0495(16)30187-1/fulltext

Sepsis is also found to be common in type 2 diabetes.

https://robbwolf.com/2012/06/28/sepsis-type-2-diabetes-cut-cloth/

An imbalance in T cells can cause Type 1 diabetes. I have post on the immune system and it covers balancing T cells.

http://diabetes.diabetesjournals.org/content/61/1/14

If type 1 diabetes is not addressed a person could develop COPD.

https://cardiab.biomedcentral.com/articles/10.1186/1475-2840-11-132

Type 1 diabetes has been linked to our gut bacteria.

https://www.sciencedirect.com/science/article/pii/S1931312815000219

Oxidative stress plays a major role in diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996922/

https://www.futuremedicine.com/doi/full/10.2217/epi-2016-0002

Infection can cause diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925815/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925815/

Most know now that GMOs, farm chemicals and vaccinations can lead to leaky gut which causes autoimmunity. This can lead to diabetes. I have posted on how to heal the gut.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886850/

http://diabetes.diabetesjournals.org/content/57/6/1470

https://www.wageningenacademic.com/doi/abs/10.3920/BM2016.0184?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed

Gmos can cause diabetes also.

https://www.naturalnews.com/045247_GMOs_weight_gain_obesity.html

Exposure to mercury as a child can cause diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661833/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661833/

Mycoplasma can cause diabetes

https://academic.oup.com/cid/article/46/1/148/337379

Supplement that are recommended for those suffering from diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202446/

For type 2 diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499308/

Berberine protects the heart in those with diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843280/

Those vaccinated have been shown to have increased risk of diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/22934546

https://www.omicsonline.org/open-access/vaccine-induced-immune-overload-and-the-resulting-epidemics-of-type-diabetes-and-metabolic-syndrome-1747-0862.S1-025.php?aid=24058

http://www.encognitive.com/node/1371

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1116914/

vaccinations linked to type 1 diabetes.

https://avvi.info/2017/09/13/study-mmr-vaccine-linked-to-type-1-diabetes/

Vaccinations are known to cause autoimmunity. Type 1 diabetes is an autoimmune disorder.

https://www.ncbi.nlm.nih.gov/pubmed/12791316

Governments hide that vaccinations are linked to diabetes.

http://www.ghostshipmedia.com/2017/01/23/swedish-public-health-authority-hid-vaccine-link-childhood-diabetes/

Many toxins especially glyphosate can cause diabetes.

https://www.emaxhealth.com/13638/people-type-2-diabetes-can-reverse-it-changing-diet-now-science-confirms-processed-foods-contain-glyphosate-which-contribute-disease

http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=9659f917-f004-4eca-9573-587c521da5db&cKey=acbc3d67-71eb-4ab2-b697-49181cdb722d&mKey=2bb00804-c880-450c-a19d-6b47d880fc09

http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=10b63037-9068-4c4c-8de8-2475d2605b26&cKey=1259f56f-90ce-4c09-a246-ee51994a9e4d&mKey=2bb00804-c880-450c-a19d-6b47d880fc09

Our food supply has been found to be heavily contaminated with pesticides and herbicides. They have been found to contribute to diabetes.

https://www.sciencedirect.com/science/article/pii/S0160412016300496?via%3Dihub

https://www.ncbi.nlm.nih.gov/pubmed/27743729

Medication have effects on our gut bacteria which can lead to diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/26756039

https://nyulangone.org/press-releases/antibiotic-treatment-increased-risk-for-type-1-diabetes-in-animal-study

If the gut bacteria are not replace it can lead to NAFLD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813164/

Leaky gut cause form toxins or even stress and inflammation can lead to diabetes and even mental illness.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478855/

This is why prebiotics have been found to aid with diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615359/

https://www.ncbi.nlm.nih.gov/pubmed/25897351

Many toxins and drugs can destroy our commensal virome part of our microbiome. Our bodies need these viruses and so do our gut bacteria to keep us healthy.

http://jvi.asm.org/content/89/4/1951.full

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4398897/

Probiotics may be needed in diabetics.

https://www.sciencedaily.com/releases/2015/09/150903131728.htm

http://diabetes.diabetesjournals.org/content/57/6/1470

Babies born to mothers through C-section and who have taken antibiotics are prone to developing diabetes.

https://www.naturalnews.com/2017-12-22-c-section-or-antibiotics-while-pregnant-give-babies-probiotics.html

They are finding that exercise and diet have little to do with determining if someone will develop diabetes. Processed food will make us prone to diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/22934546

http://www.diabetes-book.com/truth-fats-iv/

Having an imbalance in gut bacteria causes metabolic issues which can lead to diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/28701081

Vitamin D helps with type 2 diabetes.

https://www.vitamindcouncil.org/health-conditions/type-ii-diabetes/

https://www.diabetesdaily.com/blog/vitamin-d-and-its-role-in-diabetes-402285/

https://dmsjournal.biomedcentral.com/articles/10.1186/1758-5996-5-8

Mothers who are vitmamin D deficient can cause the child to be prone to diabetes.

https://www.ncbi.nlm.nih.gov/pubmed/27103201

Also babies born by C-section are more prone to diabetes. They found seeding the babies with the mothers microbiota from her vagina can help prevent this.

https://www.naturalnews.com/2017-12-22-c-section-or-antibiotics-while-pregnant-give-babies-probiotics.html

BH4 issues can cause diabetes it regulates glucose homeostasis. I have posted on BH4 and resolving BH4 issues, often times there are other issues that need addressed if there are BH4 issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414566/

https://www.ncbi.nlm.nih.gov/pubmed/23649519

Supplementing with BH4 has been shown to improve diabetes.

http://www.fasebj.org/content/30/1_Supplement/737.6

Green tea has been found to restore BH4 levels. Drinking green tea should be done in moderation. Drinking it everyday has been found to cause high histamine levels.

http://www.life-enhancement.com/magazine/article/3721-green-tea-re-establishes-tetrahydrobiopterin-levels-in-human-diabetics

Regulating BH4 levels is very improtant.

http://www.j-circ.or.jp/english/sessions/reports/71st/sym10.htm

This study discusses the many issues diabetics were found to have.

https://www.hindawi.com/journals/ijvm/2012/918267/

Issues with the Folate pathway can cause Type 1 diabetes. I wouldn’t doubt if folic acid could contribute to this. It is man made and the body does not produce enough of the enzyme needed to break it down. Many have high levels of folic acid which can effect the brain, increase our risk of cancer and have many other negative health effects on our body. Sadly the scientific and medical community use folate and folic acid interchangeably.  Science has gotten very sloppy now days. Folate is the natural form.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703744/

Some with MTHFR issues my benefit from increasing folate intake. Read my comment on this post about folic acid because they use it interchangeably and folic acid is bad.

https://www.thediabetescouncil.com/is-folic-acid-beneficial-for-diabetes/#comment-15332

Many do not know the difference between Folate and Folic acid. Folic Acid should be avoided.

https://www.ncbi.nlm.nih.gov/pubmed/16886840

Nutrients that help with diabetes.

https://www.sepalika.com/type-2-diabetes/vitamins-for-diabetics/

https://www.ncbi.nlm.nih.gov/pubmed/28335416

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5371921/

https://www.sepalika.com/type-2-diabetes/vitamins-for-diabetics/

https://www.nutritionjrnl.com/article/S0899-9007(17)30125-9/fulltext

Herbs that help with diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755736/

I do not recommend high doses of any vitamin it can make things worse. Do things in moderation.

https://www.medscape.com/viewarticle/731177

It is very important for diabetics to reduce oxidative stress.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144755/

Biotin is important for regulating glucose homostais.

https://www.ncbi.nlm.nih.gov/pubmed/28935144

Statins increase the risk of developing diabetes.

https://www.medscape.com/viewarticle/877626

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156828/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066992/

Egg consumption improves blood glucose levels.

https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/egg-consumption-as-part-of-an-energyrestricted-highprotein-diet-improves-blood-lipid-and-blood-glucose-profiles-in-individuals-with-type-2-diabetes/0D343EB44969CC003FC865D44308D7F4

http://www.mdpi.com/2072-6643/7/9/5344/htm

It is a myth that egg consumption in diabetics causes high LDL levels.

http://ajcn.nutrition.org/content/101/4/705.short

The chameleon plant helps protect pancreatic B-cells.

https://www.hindawi.com/journals/aps/2014/809438/

Sweet potato vine leaves help restore insulin sensitivity.

https://www.ncbi.nlm.nih.gov/pubmed/12870164

Processed sugar causes diabetes from causing excess oxidative stress.

http://diabetes.diabetesjournals.org/content/55/11/2939

The B Cells are very good at adapting so what goes wrong? This will be explained in the links below.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605729/

A ketogenic diet can help restore B Cells.

https://www.leafscience.org/type-1-diabetes/

Ketoacidosis can result from diabetes, this can be corrected by addressing metabolic issues. Those with type 1 diabetes can develop ketoacidosis if they try fasting.

https://www.mayoclinic.org/diseases-conditions/diabetic-ketoacidosis/symptoms-causes/syc-20371551

https://www.emedicinehealth.com/diabetic_ketoacidosis/article_em.htm

Thiamine deficiency can make ketoacidosis worse.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865064/

Metabloic syndrome is a marker used to detect diabetes.

http://care.diabetesjournals.org/content/26/11/3153

Those with type 2 diabetes secrete low levels of insulin from B cells.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434080/

Olive leaf improves insulin sensitivity and increases B-cell secretion of insulin.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596374/

There has been success using an Arab herbal combination at treating diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586306/

Okra helps with diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178946/

Jujube a member of the buckthorn family helps with many disorders including diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5174181/

Stevia leaves increase insulin sensitivity and reduces blood glucose levels.

https://www.ncbi.nlm.nih.gov/pubmed/23140911/

Burdock helps with diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355822/

Just as inflammation causes heart disease it can also cause diabetes. Stress also causes inflammation so it stands to reason that it could also cause it.

http://diabetes.diabetesjournals.org/content/57/6/1470

https://www.diabetesselfmanagement.com/blog/put-out-the-fire-of-diabetes-inflammation/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087185/

https://www.diabetesselfmanagement.com/blog/put-out-the-fire-of-diabetes-inflammation/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265866/

Paeonia helps with kidney disease caused by diabetes.

https://link.springer.com/article/10.1007%2Fs11255-016-1345-5

https://www.sciencedirect.com/science/article/pii/S0378874116305773?via%3Dihub

Stevia extract also helps protect the kidneys. Stevia the sweetener is different , it must be the extract.

https://www.sciencedirect.com/science/article/pii/S1056872712002802

Corns silk is another one that is good for all around healing.

http://www.mdpi.com/1420-3049/17/8/9697/htm

Now if you look at this study they are looking at the symptoms as usual and not the cause when it is clear the cause is inflammation and oxidative stress. So they need to find the cause and address it. Also fatty acid issues can be connected to leaky gut, gut dysbiosis and pyrrole issues which is a symptom of porphyria.

http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.906.7401&rep=rep1&type=pdf

Hibiscus taiwanensi is in the mallow family. I wouldn’t doubt if others of this family have this quality. It helps with type 2 diabetes. Because most in the mallow family have the same benefits.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652199/

Bitter melon increases the volume of islet cells in the pancreas but can have side effects.
https://www.ncbi.nlm.nih.gov/pubmed/18983991

https://www.tandfonline.com/doi/full/10.1080/13880209.2017.1396350
Bitter melon should be used with caution it can aggevate fatty liver disease.
http://pubs.acs.org/doi/abs/10.1021/pr401230s
Addressing metabolic issues helps restore B-cell funtion. I have covered some metabolic issues like sulfation . I have also covered detoxing in some of my post.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605729/
Olive oil has been shown to help with metabolic issues found in diabetic mice.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153607
https://www.future-science.com/doi/abs/10.4155/fmc-2017-0113?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=fmc
Free Fatty Acid Receptor Agonist help correct diabetes. That is why bitter melon helps it is a FFAR agonist.
http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.906.7401&rep=rep1&type=pdf

 

Fleabane may help with diabetes. Fleabane has biacelain which has many health benefits.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477270/

There are other naturals that have been researched.

https://cardiab.biomedcentral.com/articles/10.1186/1475-2840-4-5
ceremide accumulation contributes to diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839256/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279553/
Diabetes has been found to be a metabolic disorder. Proteinuria causes neuropathy in diabetes. Those with proteinuria , phenylketonuria or pyrrole issues most likely have porphyria. Those are all symptoms of porphyria which I have posted on.
http://m.cjasn.asnjournals.org/content/2/1/58.full
Flax seed helps with diabetes. It must be crushed the body cannot digest whole flax seed.
http://www.tandfonline.com/doi/abs/10.3109/19390211.2015.1036188#.WAUEeI0IKVc.facebook

https://flaxcouncil.ca/abstract/an-open-label-study-on-the-effect-of-flaxseed-powder-linum-usitatissimum-supplementation-in-the-management-of-diabetes-mellitus/

http://journals.sagepub.com/doi/abs/10.1177/0960327115571765

Phytic acid helps with insulin resistance.

https://www.precisionnutrition.com/all-about-phytates-phytic-acid
Those with diabetes have been found to have excess oxidative stress this is why Nrf2 activators can helps some with diabetes.
https://www.ncbi.nlm.nih.gov/pubmed/26165427

https://www.hindawi.com/journals/jdr/2017/4826724/

Nrf2 activators also help prevent damage to the renal system.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198074/

Rehmannia is an Nrf2 activator.

https://www.spandidos-publications.com/10.3892/etm.2017.5302

Cinnamon is an Nrfw activator.

https://www.karger.com/Article/FullText/374074
Feverfew helps with diabetes by reducing inflammation. Taking feverfew for too long can result in severe withdrawal when you quit taking it. I would only take it with colds or when symptoms are very bad.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309307/
Mtor signaling is involved in protein homeostasis and is connected to diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154417/
fasting helps restore B-cell and can help with type 1 diabetes. Those with type 1 diabetes can develop ketoacidosis when fasting so should be cautious about this one. If you were to try it I would make sure you had plenty of electrolytes and used glycoproteins or something. I would not do a complete fast. Ketoacidosis is life threatoning. This is a fasting mimicking diet. Fasting should be done intermittently. 
https://www.leafscience.org/type-1-diabetes/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168743/
Leaky gut can cause excess mtor activation which causes diabetes. I have posted on healing the gut.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468516/
Horny goat weed is an mtor inhibitor so helps with diabetes.
http://pubmedcentralcanada.ca/pmcc/articles/PMC5053690/
Burdock helps with diabetes.
http://ajp.mums.ac.ir/article_7843_0.html
Sage has been shown to be as effective as metformin against diabetes without the dangerous side effects.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003706/
Lotus seed pod ehnances glucose homeostasis.
https://www.ncbi.nlm.nih.gov/pubmed/28314100
Inhibited mTor disrupts glucose homeostasis. We need to find balance, too much mTOR causes problems and not enough does. The goal should always be to reach homeostasis.
http://diabetes.diabetesjournals.org/content/early/2017/05/20/db16-1349
GPI deficiency can result in mTor activation.
http://www.sciencedirect.com/science/article/pii/S0925443911001608
Good information on mTor

https://selfhacked.com/blog/mtor-natural-mtor-inhibitors/
Oxidative Stress causes autoimmunity which lead to diabetes.
https://www.ncbi.nlm.nih.gov/pubmed/12791316
B-cell function can be restored.
https://www.diabetesselfmanagement.com/blog/can-beta-cells-be-healed/
Gymena stimulates B-cell growth.
https://www.ncbi.nlm.nih.gov/pubmed/20537514/
Reducing blood glucose stimulates B-cell growth. This can be done by fasting.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626401/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168743/
Fluoroquinolones a dangerous antibiotic can severily impact glucose levels and cause diabetes
https://academic.oup.com/cid/article/57/7/971/338682

https://academic.oup.com/cid/article/57/7/971/338682

https://www.sciencedaily.com/releases/2013/08/130815084843.htm#.WM06AIfHrHE.facebook
Mineral water with sodium bicarbonate helps with diabetes. And fungal infections.
https://www.hindawi.com/journals/ecam/2015/824395/

https://www.diabetes.co.uk/news/2016/may/baking-soda-could-treat-rare-fungal-infection-in-diabetic-ketoacidosis-98341555.html
Iron overload can cause diabetes. Lactoferrin helps with iron overload, so does curcumine but if curcumine is taken for too long it can make you anemic because it chelates iron.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648340/
It used to be believed that the pancrease cannot regenerate but they have found that it can regenerate.
https://www.bensprostate.com/pancreas-regenerate/
https://www.pancreapedia.org/reviews/pancreatic-regeneration-models-mechanisms-and-inconsistencies
https://www.hindawi.com/journals/isrn/2012/640956/
Even those who have had diabetes for many years still have B-cell function
http://care.diabetesjournals.org/content/35/3/465
http://www.oatext.com/Increased-fasting-and-stimulated-c-peptide-levels-after-the-diagnosis-of-type-1-diabetes-a-case-report.php
Fasting is one way to stimulate pancreatic regeneration.
http://www.cell.com/cell/fulltext/S0092-8674(17)30130-7
We must make sure we address autoimmune issue to get pancreatic cells to regenerate. I have posted on that also.
https://www.nature.com/articles/nature13633
Tumeric can help regenerate B-cells. Must be careful using it though it chelates iron and can cause anemia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176754/

Yarrow helps with a lot of things.

https://www.medel.la/search/results?utf8=✓&key_word=diabetes

Kudzu root is another thing that helps with a lot of things.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784920/

Vitamin D helps pancreas regenerate B-cells
https://www.nature.com/articles/srep10411
A1C is a measurement of how many red blood cells have glucose attached. It can be reduced by eating certain foods and other natural methods.
https://www.niddk.nih.gov/health-information/diabetes/overview/tests-diagnosis/a1c-test
https://www.curejoy.com/content/ways-to-lower-hemoglobin-a1c-levels-naturally/
http://a1cguide.com/foods-lower-a1c/
https://beyondtype1.org/secrets-to-lowering-your-a1c-a-diabetic-health-coach-gives-us-the-scoop/
Good information on preventing diabetes.
https://draxe.com/prediabetes-symptoms/
The ketogenic diet helps with type 2 diabetes.
https://www.ruled.me/lower-blood-sugar-naturally/

https://www.sciencedaily.com/releases/2011/04/110420184429.htm
Pumpkin seed helps with type 2 diabetes.
https://www.ncbi.nlm.nih.gov/pubmed/11483384
https://www.researchgate.net/publication/263652319_Effects_of_Cucurbita_ficifolia_Intake_on_Type_2_Diabetes_Review_of_Current_Evidences

Dandelion is another one of those plants that help with many things.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635758/

I have never tried cissus but my friend say it is fantastic.

https://www.organicfacts.net/health-benefits/other/cissus-quadrangularis.html

Camu Camu helped me a lot, it also raises GABA levels so would help with anxiety.

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000100355

Self Heal is another herb with many healing abilities.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269750/
The antioxidant effects of phyto chemicals from many plants can help protect the pancreas and help with healinng.
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100001
http://www.greenmedinfo.com/blog/10-natural-substances-may-help-cure-type-1-diabetes

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586306/

I consider saffron a super herb, it helps with a lot of things.

https://www.sciencedirect.com/science/article/pii/S0019483216301924?via%3Dihub

This list of plants has sage which is another super herb for healing.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003706/

Muscadine grapes help with diabetes.

https://iubmb.onlinelibrary.wiley.com/doi/abs/10.1002/biof.5520300306

Canola oil causes diabetes but Omega 3 oils reduce it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267437/

Metabolic, inflammation and infection can cause thrombosis and fibrosis. These are found to be common in diabetes so if someone has diabetes they need to address the cause of the oxidative stress , inflammation or metabolic issues or whatever else is causing the health problems. Diabetes is a symptom not a cause. Allopathic medicine only looks at and treats symptoms they do not address the cause. There is no money in curing. A healthy patient is a lost customer. These are a sign of endothelial dysfunction.

http://www.scielo.br/scielo.php?pid=S1516-84842010000600013&script=sci_arttext&tlng=en

https://www.hindawi.com/journals/ijvm/2012/918267/

Folate helps with endothelial dysfuncton. They say folic acid, for some reason many medical professionals use the term folate interchangebly with folic acid which most know by now is toxic to the body. I do not know if they are doing it to promote it for better sales or if they are in error or are just doing sloppy science but folic acid can be toxic to the body. Folate is the safe one it is natural.

http://journals.sagepub.com/doi/abs/10.1191/1358863x06vm664oa?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

Activating Sirt1 helps with diabetes.

http://joe.endocrinology-journals.org/content/237/1/1.long

There are natural Sirt1 activators like resveratrol found in grape seed extract.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727669/

https://www.hindawi.com/journals/omcl/2016/4206392/

https://www.researchgate.net/figure/Sirtuin-activators-of-natural-resveratrol-curcumin-and-quercetin-and-synthetic_fig1_233749168

Alpha Lipoic acid is a sirt activator.

https://link.springer.com/article/10.1007%2Fs00125-012-2530-4
We should avoid GMOs they have been found to alter the pancrease.
http://onlinelibrary.wiley.com/doi/10.1002/jat.1319/full
Autoimmune dysfunction has been mistaken for pancreatic cancer.
https://www.mdedge.com/ccjm/article/95018/gastroenterology/autoimmune-pancreatitis-mimic-pancreatic-cancer
Emoden is found in buckthorn and Japanese Knotweed. It can stimulate B-cell regenerations.
https://www.ncbi.nlm.nih.gov/pubmed/12142738
Herbs that reduce glucose levels stimulate B-Cell growth
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626401/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591578/
Rooibos protects pancreatic cells from cell death. Aspalathus linearis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907458/

Symptoms of pancreatitis.

https://fabiosa.com/rser-aulk-every-meal-stomachache-radiating-back-never-suspected-pancreatitis-serious-health-issue-1/?utm_source=fab_philippines&utm_medium=rpost&utm_campaign=ed
Drinking soda has a dramatic negative impact on the pancreas and can lead to pancreatic cancer. There are many habits we have that negatively impact the pancreas.
https://www.naturalmedicinejournal.com/journal/2010-03/data-clearly-links-soda-consumption-pancreatic-cancer

http://www.healthybuilderz.com/common-habits-bad-pancreas/

It is very important to protect the pancreas because it produces many of the enzymes we need for digestion.

https://www.laparoscopic.md/digestion/pancreas

If we do not address the thing that cause metabolic issues. We could develop many health issues because of the impact on the pancreas. This could eventually lead to gall stones.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784862/

It is very important to address acidosis , it destroys the pancreas. I have posted on acidosis.

http://pancreas.imedpub.com/chronic-metabolic-acidosis-destroys-pancreas.php?aid=164
Type 3c diabetes is often misdiagnosed and over looked because it is caused by issues in the brain.

http://care.diabetesjournals.org/content/40/11/1486

http://www.diabetesincontrol.com/awareness-of-type-3c-diabetes-and-why-it-is-misdiagnosed/
https://asweetlife.org/what-is-type-3c-diabetes/
https://www.pancreapedia.org/reviews/pancreatogenic-type-3c-diabetes

There are biomarkers to distinguish between the two.
http://gut.bmj.com/content/67/1/128
Those with type 3c diabetes have been found to be vitamin D deficient.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831209/
It is dificult to balance insulin levels in Type 3c diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003514/
https://www.ncbi.nlm.nih.gov/pubmed/21757968
Type 3c diabetes is cause by brain issues. Things that help the brain also help Type 3c diabetes.
https://www.adwdiabetes.com/articles/type-3-diabetes-brain-health
http://www.natureandhealth.com.au/health/type-3-diabetes
Type 3c diabetes my contribute to alzheimers.
http://www.greenmedinfo.com/blog/sugar-and-your-brain-alzheimer’s-disease-actually-type-3-diabetes
http://www.practicaldiabetes.com/article/type-3-diabetes-brain-insulin-resistant-state-linked-alzheimers-disease/
Habits that are bad for the pancreas.
http://www.healthybuilderz.com/common-habits-bad-pancreas/
Symptoms of pancreatitis.
https://fabbiosa.com/rser-aulk-every-meal-stomachache-radiating-back-never-suspected-pancreatitis-serious-health-issue-1/?utm_source=fab_philippines&utm_medium=rpost&utm_campaign=ed
Pancreatitis can lead to diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784862/
http://www.laparoscopic.md/digestion/pancreas
Many things including drugs can cause pancreatitis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518169/
Acidosis harms the pancreas. I have posted on acidosis and alkalosis.
http://pancreas.imedpub.com/chronic-metabolic-acidosis-destroys-pancreas.php?aid=164
Often times IL-35 is increased in those with diabetes and pancreatic cancer.
https://www.ncbi.nlm.nih.gov/pubmed/28620093

https://www.ncbi.nlm.nih.gov/pubmed/29033948

https://www.ncbi.nlm.nih.gov/pubmed/25073578

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709038/
Heparin cofactor II regulates the homeostasis of IL-12 family. IL-35 is a member of the IL-12 family. Heparin cofactor II has been found to be low in diabetics.
https://www.karger.com/Article/Pdf/216150
A cells can become B cells.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605721/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209186/

Phyto therapy for B cells

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100001
A1C is not a reliable test

https://chriskresser.com/why-hemoglobin-a1c-is-not-a-reliable-marker/

http://care.diabetesjournals.org/content/34/Supplement_2/S184

If the diabetes is not addressed it can lead to cancer.

https://www.hindawi.com/journals/mi/2016/6456018/

Mast cells activation syndrome has been connected to many chronic diseases including diabetes. I have covered this in my post on autoimmune and how to address it but I may if time permits do a post specifically on mast cells.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318912/

Some naturals that may help.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990312/

https://draxe.com/pine-bark-extract/

http://www.organichealthuniverse.com/2016/08/31/moringa-herb-kills-cancer-stops-diabetes/

Eggs should be included in a diet for better health.

http://www.mdpi.com/2072-6643/7/9/5344/htm

https://academic.oup.com/ajcn/article/101/4/705/4564505

Chlorine is toxic to the body. Fluoride is a biproduct along with bichlroides and trichlorides which are also very toxic. Drinking water with fluoride in it increases the risk of getting diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116242/

They are getting close to developing new non invasive diagnostic tools for diabetes.

http://pubs.rsc.org/en/Content/ArticleLanding/2017/PP/C6PP00431H#!divAbstract

Fiber increases the good gut bacteria which reduces diabetes.

https://onlinelibrary.wiley.com/doi/abs/10.1002/dmrr.2518

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000300013

Nicotinomide riboside helps with mitochondrial issues in diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718430/

To get the gut bacteria to remain and thrive we need Akkermansia Munciniphila.

https://biofoundations.org/increasing-and-maintaining-akkermansia-muciniphila-for-a-healthy-gut-microbiome/

These studies frustrate me. Instead of looking at what is causing the bile issues they are looking at the symptoms and how to resolve them. The symptoms are not the cause. They need to be checking for leaky gut, gut dysbiois, infections , metabolic issues or nutrient deficiencies. Or causes of inflammation they can all effect bile production and reabosorption. Science does not seem to be real anymore they all seem to have tunnel vision shaped by corporate science.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535499/

Bile acids are responsible for many things in the body and if it becomes inhibited even our ability to detox will be inhibited and oxidative stress will increase and will will start developing issues with fat digestion.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811459/

http://jem.rupress.org/content/early/2018/01/12/jem.20171965.long

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397342/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128138/

https://www.hindawi.com/journals/jl/2012/754067/

Posting these links to demonstrate something. Inflammation, oxidative stress and many other things cause Fe3 to build up in the body to cause iron toxicity. The body cannot use Fe 3. Lactoferrin and curcumin reduce Fe3 . This would increase Gs/1 which should let B cell grow. Because Fe3 cannot be used by the body it would work as if a person was deficient in iron. They chelate iron from the body to fight cancer because it reduces Gs/1.  So by reducing Fe3 in the body it would let our bodies restore iron levels back to normal which should promote B cell growth. I could find little research to verify what I believe but I am convinced it would help.

https://www.ncbi.nlm.nih.gov/pubmed/12807743

http://clinchem.aaccjnls.org/content/50/9/1640.long

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120169/

http://www.drlwilson.com/articles/IRON.htm

TMAO increases the risk of diabetes and heart disease, high meat consumption and certain gut bacteria produce TMAO. Grape seed extract, wine and olive oil prevent the gut bacteria from producing TMAO.

https://www.cell.com/cell-reports/fulltext/S2211-1247(17)30751-9

Excess CB1 receptor activation can lead to diabetes and liver damage.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839256/

Cannabis is a CB1 inhibitor.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664820/

Black pepper is a CB1 inhibitor.

https://pubs.acs.org/doi/full/10.1021/acs.jafc.7b02979

Autstralian cowplant is interesting. It helps with both type 1 and type 2 diabetes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912882/

Viral infections protect and can even heal diabetes.

https://www.jci.org/articles/view/17005

It is very important to reduce stress.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144755/

Endothelins can effect the heart and cause insulin resistance.

https://www.selfhacked.com/blog/endothelins/?utm_source=ActiveCampaign&utm_medium=email&utm_content=The+Latest+From+SelfHacked&utm_campaign=Jan282018+Newsletter

I stand corrected I guess diet can help control the glycemic index in some.

https://www.cell.com/cell/fulltext/S0092-8674(15)01481-6

White malberry helps with insulin resistance.

http://www.mdpi.com/1422-0067/19/5/1542

Beta Glucan helps reverse type 2 diabetes.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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High Ammonia/Alkalosis Levels in chronic illness.

Ammonia is very toxic to the body and can be formed when there are too many toxins, endotoxins can cause it, vitamin deficiencies, infections, farm chemicals in our food, vitamin deficiencies can cause it and oxidative stress can cause high ammonia levels. When we have high ammonia levels it alkalize our digestive system and our bladder. They are normally acidic. Most pathogens thrive in an alkaline environment. Candida goes from commensal to pathogenic in an alkaline environment and then it will start to alkalize even more. This kills our good bacteria that regulates our gut and bladder PH. I rarely ever fart now I have reach gut homeostasis.

If not addressed it can cause brain swelling.

http://www.neuroradiologycases.com/2012/02/hyperammonemic-encephalopathy-mri.html

Toxins can cause Lysinuric protein intolerance which causes high ammonia levels when protein is consumed. I did a post on proteinuria it should help with this. If not addressed this can lead to copd or NAFLD.

https://ghr.nlm.nih.gov/condition/lysinuric-protein-intolerance

One of the differences between acidosis and alkalosis is that nerves become hyper sensitive in alkalosis and we become excitable. In acidosis nerves are depressed and we become drowsy. Alkalosis is usually caused by fungal infections acidosis by infections that produce endotoxins like Lyme or a viral infection.

http://drbenkim.com/ph-body-blood-foods-acid-alkaline.htm

Symptoms include brain fog, depression, delusions, neurological problems, swelling in the throat, gut dysbiosis, interstitial cystitis or frequent bladder infections, gall stones the list goes on and on.

http://mbio.asm.org/content/2/3/e00055-11.full

https://www.thecandidadiet.com/ph-levels-candida/

https://www.candidaplan.com/10-candida-myths-2/

One of the differences between acidosis and alkalosis is that nerves become hyper sensitive in alkalosis and we become excitable. In acidosis nerves are depressed and we become drowsy.

http://drbenkim.com/ph-body-blood-foods-acid-alkaline.htm

High ammonia levels will cause high glutamate levels which will cause anxiety and many other mental issues.

http://www.ucl.ac.uk/~ucbcdab/urea/amtox.htm

http://onibasu.com/wiki/Elevated_ammonia.html

https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.21357

In acidosis a person will have high plasma potassium levels and in alkalosis they will have low potassium levels.

https://acutecaretesting.org/en/journal-scans/on-the-relationship-between-potassium-and-acid-base-balance

Glyphosate which is found in most of our food causes a mineral imbalance which can cause high ammonia levels.

https://www.frontiersin.org/articles/10.3389/fphys.2017.01083/full

https://www.frontiersin.org/articles/10.3389/fnbeh.2017.00146/full

It can also lead to neuropathy.

https://www.jstage.jst.go.jp/article/internalmedicine/56/11/56_56.8064/_article

http://surgicalneurologyint.com/surgicalint-articles/glyphosate-pathways-to-modern-diseases-iii-manganese-neurological-diseases-and-associated-pathologies/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312745/

Infections especially Lyme can cause high ammonia levels. Ammonia alkalizes and we are supposed to be acidic.

http://planetthrive.com/2010/12/the-alkaline-brain/

Our bladders are supposed to be acidic. Infection can make them alkaline which kills our good bacteria.

https://www.jstage.jst.go.jp/article/jjaam/23/9/23_398/_article

CBS issues can cause high ammonia levels.

https://drjockers.com/cbs-mutation-low-sulfur-diet/

High ammonia levels causes brain swelling.

http://www.neuroradiologycases.com/2012/02/hyperammonemic-encephalopathy-mri.html

Pathogens thrive in an alkaline environment and will cause ammonia to be produced to protect themselves that is why it is important to get ammonia levels down.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677674/

https://www.jstage.jst.go.jp/article/jjaam/23/9/23_398/_article

http://mbio.asm.org/content/2/3/e00055-11

Protein intolerance can cause this. I addressed that in my post on porphyria. Protein intolerance is one symptom of porphyria. It is referred to as phenylketonuria when you eat protein or foods high in phenylalanine you will get sicker.

https://ghr.nlm.nih.gov/condition/lysinuric-protein-intolerance

https://www.mgmjournal.com/article/S1096-7192(05)00238-6/fulltext

Supporting the BH4 pathway to correct phenylketonuria is very important. It is one of the causes of autism.

http://journals.sagepub.com/doi/full/10.1177/2326409816685734

https://autismmasterycourse.com/wp-content/uploads/2016/08/Neurochemical-Imbalances-and-Autism-Tetrahydrobiopterin-Metabolism-and-Quinolinic-Acid-Toxicity.pdf-8-15-16.pdf

If you have a blocked or upregualted CBS pathway , or an upregulated BH4 pathway and don’t address it this could make you ill. Most with those issues would benefit from taking P5P, selenium, and magnesium citrate. Also three times a week molybdenum and manganese. Do not use magnesium citrate more then twice a week. The body recycles it and it can build up in the body and start causing liver and kidney damage and destroy red blood cells. Citrate also reduces oxalates. 

https://www.uofmhealth.org/health-library/hn-1247002

http://www.detoxpuzzle.com/bh4.php

If not addressed you can have seizures,depression, difficulty swallowing and many other problems.

https://www.medicinenet.com/tetrahydrobiopterin_deficiency/article.htm#what_are_the_symptoms_of_tetrahydrobiopterin_deficiency

https://www.selfhacked.com/blog/tetrahydrobiopterin-bh4-role-body-buy/

http://www.beyondmthfr.com/mthfr-depression-folate-bh4-connection/

It is very important to address the things that cause nitrosative and oxidative stress. Things like inflamation, nutrient deficiencies, infection, metabolic issues. They both can cause high levels of ammonia.

https://www.sciencedirect.com/science/article/pii/S0197018612003506?via%3Dihub

https://www.sciencedirect.com/science/article/pii/S0003986113000982?via%3Dihub

The liver and kidneys are important for detoxing ammonia. These herbs really help. Remember homeostasis is he goal. Do things in moderation.

https://www.cancertutor.com/faq_liver_damage/

https://www.selfhacked.com/blog/liver-health-foods-supplements-good-bad-liver/

https://www.drweil.com/health-wellness/body-mind-spirit/liver-kidney/boosting-kidney-function/

https://www.globalhealingcenter.com/natural-health/10-best-herbs-kidney-cleansing/

We need glucose found in fruits and vegetables and even honey, maple syrup and organic unsulfured blackstrap molasses to keep ammonia levels down.

https://www.physiology.org/doi/10.1152/ajpgi.00437.2002

http://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-13-2-177

http://www.pnas.org/content/108/27/11121

Issues with our CBS pathway could also cause high ammonia levels. Anything that causes high sulfite levels can cause high ammonia levels. Gene mutations only present when there are many things wrong, once I got my ammonia levels and sulfite levels down I could start consuming high sulfur foods again. I still take the nutrients once in a while to support those pathways so it does not become a problem again. Glyphosate also effects the pathways negatively so we should try our best to eat organic. Also if we have gut dysbiosis then we need to address that because that raises our sulfite and hydroxy radical levels which also causes high ammonia levels.

https://www.drlam.com/blog/a-cbs-mutation-could-be-causing-your-health-problems/34861/

https://drjockers.com/cbs-mutation-low-sulfur-diet/

https://metabolichealing.com/metabolic-gateways-cbs-gene-mutations-glutathione/

https://hubpages.com/health/How-to-lower-ammonia-for-those-dealing-with-A1298-NOS-SUOX-and-CBS-mutations

If we have an infections the endotoxins effect these pathways which will raise ammonia levels so we need to detox endotoxins which I covered in my post on how to recover from endotoxemia.

http://www.tiredoflyme.com/ammonia-a-lyme-disease-exotoxin.html

Gut dysbiosis causes high ammonia levels, from the high sulfite levels. This effects the brain.

http://drstephaniedavis.com/gut-dysbiosis-making-sick/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259177/

This adds to the problem because high sulfite levels keeps the good gut bacteria from reestablishing.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5646858/

http://altmedrev.com/archive/publications/9/2/180.pdf

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508456/

https://www.badgut.org/information-centre/a-z-digestive-topics/the-role-of-sulphur-in-uc/

Bismuth which is what Pepto Bismo is , reduces sulfide levels.

https://www.ncbi.nlm.nih.gov/pubmed/9558280

https://www.thesibodoctor.com/2017/12/20/sibo-and-hydrogen-sulfide/?v=7516fd43adaa

Not getting enough cholesterol, high sulfite level, and oxidative stress can inhibit bile production. This make H Pylori go from commensal to a pathogenic form. Bile helps detox ammonia from the body. If it feels like a brick is in your stomach after you eat and you get gassy then you have low bile production which will lead to low stomach acid production. Your food is fermenting instead of being digested which will also cause high sulfite levels and high ammonia levels.

https://link.springer.com/article/10.1023/A:1010678210019

https://metabolichealing.com/l-glycine-brain-gut-tissues/

Low bile will inhibit our ability to break down fats which are needed by the body.

http://askanaturopath.com/faqs/low-bile-salts/p/712

https://www.liverdoctor.com/gallbladder-and-digestive-problems/

Things that increase bile.

http://healthyeating.sfgate.com/foods-increase-bile-flow-8649.html

https://metabolichealing.com/unclogging-the-liver-advice-ideas-for-one-of-the-most-vital-and-massive-organs/

https://drjockers.com/25-ways-improve-gallbladder-health/

Taurine helps increase bile productions.

http://www.jlr.org/content/28/9/1021.long

Butyrate produced by our gut bacteria protect the gut and the gut bacteria. When we are low in butyrate our gut becomes inflamed. I ate butter or ghee which is high in butyrate. Our butyrate producing bacteria even regulate our metabolism.

https://www.sciencedirect.com/science/article/pii/S2405654517301397

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517538/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099420/

Zinc helps reduce ammonia levels.

https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.1840160326

Calcium D-Glucurate helps reduce excess ammonia.

https://blog.bulletproof.com/calcium-d-glucarate/

Bicarbonate rich mineral water will reduce ammonia.

https://www.hindawi.com/journals/ecam/2015/824395/

Hyper Excitement of NMDA (autism also known as encephalitis)

This is not medical advice I am posting this for informational and educational purposes.

stock-photo-concept-of-human-intelligence-with-human-brain-on-blue-background-294471983

The NMDA receptors in the brain is one of the most effected when we are ill. It can cause blurred vision, trouble with light it will glare to those effected. You may get buzzing in the ears. It can cause bipolarism, autism , schizophrenia, dissociative behavior and tunnel vision among many other issues.

Most things like metabokic issues , oxidative stress, autoimmunity that I mention in here I have posted on and you can find it using the search feature in my blog.

NMDA Receptors

Information on how the NMDA receptor functions.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1760733/

L-glutamate or glutamic acid is one of the most important of the excitatory neurotransmitters. It is released by many different types of neurons and stimulates other neurons at the synapses. The excitatory neurotransmitters act to stimulate the next neuron to fire.

Excitotoxicity is when levels of excitatory neurotransmitters are to high, at which point the level of neuronal activation or induced firing of neurons becomes damaging.

GABA inhibits firing of neurons. GABA is synthesized from glutamine. It needs the active form of B6, pyridoxal phophate. When there have been inhibitions in metabolic pathways the body may not be able to convert the B6 to the active form causing a build up of glutamine or glutamate. This can lead to dysfunction in the brain. It can also lead to high ammonia levels. Raised ammonia levels can kill our good gut bacteria and let the sulfur digesting and methane producing bacteria increase in numbers. This will also happen in the bladder. Also high ammonia levels will make candida go from commensal to pathogenic form. This will cause high sulfite levels which will interfere with BH4, I discussed earlier the problems that creates. The high sulfite levels can also cause problems with the CBS pathway which can eventually effect the Krebs Cycle.

GABA and glutamate are balanced in the brain . P5P deficiency can result in elevated glutamate to GABA ratio in the brain which results in elevated levels of exitotoxicity.

https://www.ncbi.nlm.nih.gov/pubmed/17127302

Taurine performs manby vital functions in the body including nutritional metal transport into the cells.

L-glycine is an inhibitor of neurotransmitter.

N-Methyl-D-Aspartate (NMDA) receptors found in various nerve cells or neurons in the brain. They are stimulated by glutamate and aspartate (aspartic acid). There are 4 main types of of neurotransmitters. NMDA, AMPA, Kainate and Metabotropic receptors.

NMDA primary role is to respond to glutamate or aspartate. NMDA is also stimulated by glycine and polyamines. Aspartate is also involved in the Krebs cycle. Polyamines are interesting, they do not know a lot about them but from what I have read they are almost like software that will zip or compress files then decompress them. They also have a lot of other functions.

Post synaptic NMDA receptor hyper excitement by the presence of elevated glutamate and aspartate levels and/or insufficient GABA, Taurene or Glycine levels results in the receptor opening a channel in the cell membrane allowing the influx of calcium (Ca2+) ions and a reduction of potassium (k+) ions. This has been linked to many brain disorders and it is a common theme in a variety of disorders effecting the brain. The influx of calcium into the cells stimulates NOS leading to NO production in post synaptic cells. I discussed eNOS and iNOS in my post on Nitrosative Stress. Most of the NO production in the NMDA receptor is from nNOS. This can increase peroxynitrite levels because of elevated superoxide levels from oxidative stress. This can damage the brain and blood brain barrier. This can also deplete ATP , when ATP levels are low the NMDA receptors become hyper sensitive.

When the NMDA receptor is hyper sensitive a person will become sensitive to many thing, sound, light, certain odors especially toxic ones. It can make a person sensitive to chemicals because of the over stimulation.

problems with the NMDA recptor can cause the immune system to be inhibited

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586474/

NMDA issues can also have effects on the heart.

https://www.ncbi.nlm.nih.gov/pubmed/27561785

There is a connection between the NMDA receptor and pancreatic cancer.

https://www.dovepress.com/nmda-receptors-are-important-regulators-of-pancreatic-cancer-and-are-p-peer-reviewed-article-CPAA

Issues with the NMDA receptors can result in chemical sensitivities.

https://www.ncbi.nlm.nih.gov/pubmed/12205032

Copper moduclates the NMDA receptor. When we have an infection our bodies will hide copper in our soft tissue. This can make us appear to be deficient in copper. Vitamin C frees the copper from our soft tissue. Do not take too much, in high doses vitamin C destroys red blood cells. If you are deficient in copper liquid chlorophyll is a good source of copper.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382327/

https://www.hindawi.com/journals/ijad/2011/292593/

https://www.hindawi.com/journals/omcl/2014/147251/

Vitamin C interacts with the NMDA receptor to reduce pain. Has been shown to help with sciatica.

https://www.ncbi.nlm.nih.gov/pubmed/28902622

Most know vaccinations damage the brain.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297824/

http://n.neurology.org/content/86/16_Supplement/P5.136

https://www.ncbi.nlm.nih.gov/m/pubmed/25081016/?i=5&from=%2F26844739%2Frelated

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1936221/

It is a good idea to learn the symptoms because damage to the NMDA receptor is common in those vaccinated.

http://pediatrics.aappublications.org/content/138/3/e20160901?download=true

http://www.sciencedirect.com/science/article/pii/S2214250914000262

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297824/

Information on NMDA and supplements that help with NMDA issues.

https://www.wellnessresources.com/news/when-ssris-fail-causes-of-depression-nutrition-for-your-brain

Magnesium and Zinc helps to counter the influx of Ca2+ from the NMDA stimulation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122891/

Restless legs has been caused by high glutamate levels.

http://www.rlcure.com/glutamate.html

High ammonia levels will cause high glutamate levels.

http://www.ucl.ac.uk/~ucbcdab/urea/amtox.htm

Oxidative stress.

https://www.sciencedirect.com/science/article/pii/S1011134417307030?via%3Dihub

https://www.ncbi.nlm.nih.gov/pubmed/16766163

https://www.ncbi.nlm.nih.gov/pubmed/24814387

http://thescipub.com/html/10.3844/ajbbsp.2008.73.84

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5881419/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965765/

How the body regulates glutamate levels and how to protect the brain.

https://www.ncbi.nlm.nih.gov/pubmed/26711497

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431845/

http://nancymullanmd.com/glutamate-and-gaba-balance/

http://www.holistichelp.net/blog/how-to-increase-gaba-and-balance-glutamate/

http://www.jneurosci.org/content/25/26/6084

http://dana.org/Cerebrum/Default.aspx?id=39382

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134390/

http://journals.sagepub.com/doi/pdf/10.1177/0300060517693423

https://www.ncbi.nlm.nih.gov/pubmed/25433158

The blood brain barrier.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687937/

Glyphosate, this has been found to be in very high levels in our food supply. They have found the environment is so contaminated that it is even in the air and rain. So almost all have glyphosate in them.

https://www.ncbi.nlm.nih.gov/pubmed/28627408

https://www.sciencedirect.com/science/article/pii/S0300483X14000493

Inflammation

https://neuroshaman.wordpress.com/2016/01/23/kynurenic-acid-a-factor-for-schizophrenia-and-autism/

BH4 and autism.

https://autismmasterycourse.com/wp-content/uploads/2016/08/Neurochemical-Imbalances-and-Autism-Tetrahydrobiopterin-Metabolism-and-Quinolinic-Acid-Toxicity.pdf-8-15-16.pdf

The NMDA receptor has been tied to interstitial cystitis.

http://inter-use.com/Journals/JSAB/2015/Volume_03_Issue_04/2015/0507/96.html

Brain and gut.

https://www.wellnessresources.com/news/when-ssris-fail-causes-of-depression-nutrition-for-your-brain

https://link.springer.com/article/10.1007/s00787-017-1056-1

https://www.ncbi.nlm.nih.gov/pubmed/9881820

https://www.ncbi.nlm.nih.gov/pubmed/29090837/

https://www.ncbi.nlm.nih.gov/pubmed/20359266

https://www.nature.com/articles/nature22075

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068444

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879184/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228144/

https://www.selfhacked.com/blog/gut-bacteria-microbiome/?utm_source=ActiveCampaign&utm_medium=email&utm_content=ICES%2FPEMF%2C+Ceylon+Tea%2C+Gut+Microbiome+Affects+%2B+Management%2C+Purple+Sweet+Potato%2C+Myostatin%2C+Hyperbaric+Oxygen+Therapy&utm_campaign=Mar42018+Newsletter

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040025/

https://www.cell.com/cell/fulltext/S0092-8674(15)00248-2

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169303

https://www.researchgate.net/publication/312447778_Lactobacillus_plantarum_CCFM639_can_prevent_aluminium-induced_neural_injuries_and_abnormal_behaviour_in_mice

https://thevaccinereaction.org/2016/09/role-of-the-microbiome-in-infant-development/

https://www.ncbi.nlm.nih.gov/pubmed/18283240

https://kresserinstitute.com/gut-circadian-rhythm-connection/

https://www.honeycolony.com/article/trust-your-gut-health/

http://www.greenmedinfo.com/blog/vaccine-injury-first-gut-then-brain

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572414/

GMOs and the farm chemicals used on them cause leaky gut. This is a cause of autism.

https://molecularautism.biomedcentral.com/articles/10.1186/s13229-016-0110-z

https://www.theunion.com/news/twi/glyphosate-roundup-and-its-link-to-celiac-disease-gluten-intolerance/

https://detoxproject.org/glyphosate/glyphosate-and-roundup-negatively-affect-gut-bacteria/

http://autismcoach.com/glyphosate-folic-acid-oxalic-acid-vaccines-and-tylenol-wreak-metabolic-havoc-together/

https://www.ncbi.nlm.nih.gov/pubmed/25883837

https://www.cell.com/cell/fulltext/S0092-8674(16)30730-9

http://journals.sagepub.com/doi/pdf/10.1177/0300060517693423

Getting GMOs out of the diet helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550406/

http://www.autismone.org/content/autism-explained-synergistic-poisoning-aluminum-and-glyphosate-stephanie-seneff

https://www.youtube.com/watch?v=kzHXuMIsZTA

http://www.mdpi.com/1099-4300/15/4/1416

Our toxic food.

https://bebrainfit.com/neurotoxins-foods/

https://chriskresser.com/beyond-msg-could-hidden-sources-of-glutamate-be-harming-your-health/

http://www.holistichelp.net/toxins.html

https://www.dementia.org/study-links-diacetyl-to-alzheimers-disease

https://www.sciencedirect.com/science/article/pii/S0300483X14000493

Our parents past can have effects on our brain.

https://www.whatisepigenetics.com/a-fathers-stress-felt-for-generations/

https://www.madinamerica.com/2013/05/starvation-what-does-it-do-to-the-brain/

http://europepmc.org/articles/PMC4333222

How infection causes NMDA issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635055/

https://www.ncbi.nlm.nih.gov/pubmed/28484451

Our environment.

https://www.ncbi.nlm.nih.gov/pubmed/26721368

http://www.chemtrust.org/brain/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914412/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428475/

Proton Pump inhibitors damage the brain.

https://jamanetwork.com/journals/jamaneurology/fullarticle/2487379?utm_source=facebook&utm_medium=social_jamaneur&utm_campaign=article_alert&utm_content=automated

Endotoxins can contribute to NMDA excitability. Astaxanthin helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746928/

https://docs.google.com/document/d/19UH1Jfe0qlPrKunC36yZVXZcuRLx_f8MslQdSXkV8pA/mobilebasic

https://autismrecoverytreatment.com/autism-treatment-–-quinolinic-acid-and-autism/

A number of autism studies and causes.

https://medel-la-production.s3.amazonaws.com/uploads/attach_document/document_file/59cda6fe69702d2351c80600/autism-studies-april-2008-2.pdf

Over active immune response which can be caused by tick born illness, vaccinations or glyphosate.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921406/

Inflammation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753746/

http://www.cytokines-and-depression.com/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535916/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961620/

Inflammation from Lyme can even cause aneurysms.

https://jnnp.bmj.com/content/64/5/636

https://www.madinamerica.com/2017/03/lyme-wake-up-call/#comment-125698

https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-5-40

https://www.ncbi.nlm.nih.gov/pubmed/24604078

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481283/

https://www.linkedin.com/pulse/your-brainon-lyme-lori-dennis-ma-rp/?trk=prof-post

Oxidative stress

http://www.eurekaselect.com/101108/article

Immune system

https://reliawire.com/immune-system-social-behavior/?utm_content=buffer5f170&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer

https://www.ncbi.nlm.nih.gov/pubmed/23867105

http://neurosciencenews.com/schizophrenia-immune-disorder-bipolar-8179/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143489/

Encephalitis is part of the illness.

https://aealliance.org/patient-support/symptoms/

http://www.pandasnetwork.org/wp-content/uploads/2013/07/Autoimmune_encephalitis.pdf

Brain being deprived of cholesterol. This shows how statins cause it but metabolic issues can also cause this.

https://www.westonaprice.org/health-topics/modern-diseases/dangers-of-statin-drugs-what-you-havent-been-told-about-popular-cholesterol-lowering-medicines/

https://www.medicalnewstoday.com/articles/321115.php

http://www.greenmedinfo.com/blog/underreported-dangers-low-cholesterol

https://www.theautismexchange.com/organized-information/biomedical/conditions/low-cholesterol

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005588/

https://www.ncbi.nlm.nih.gov/pubmed/?term=PMC5806328

https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-016-0877-8

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487843/

This I have researched it is caused by oxidative stress from toxins.

https://www.medel.la/card_collections

Fluoride damages the brain.

https://www.researchgate.net/publication/291795479_Effects_of_endemic_fluoride_poisoning_on_the_intellectual_development_of_children_in_Baotou

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997496/

https://www.hsph.harvard.edu/news/features/fluoride-childrens-health-grandjean-choi/

https://www.ncbi.nlm.nih.gov/pubmed/25577494

https://www.ncbi.nlm.nih.gov/pubmed/25556215

Fluoroquinolone drugs destroy the brain.

https://floxiehope.com/2015/06/13/hacking-fluoroquinolone-toxicity-via-the-nervous-system/

Reversing autism

https://www.youtube.com/watch?v=m2PyRhOSYBY

http://healing-arts.org/children/mtpromotion.htm

Certain metabolic issues caused by toxins, infection or nutrient deficiencies can cause high ammonia levels which can lead to brain injury. These can be caused by nutrient deficiencies, toxins, vaccine injury, inflammation, over active immune system or infection. Many studies have connected metallothionein deficiency with autism.

http://www.neuroradiologycases.com/2012/02/hyperammonemic-encephalopathy-mri.html

https://academic.oup.com/ajcn/article-abstract/80/6/1611/4690493?redirectedFrom=fulltext

http://www.cease-therapy.com/treatment/metallothionein/

https://epidemicanswers.org/metallothionein-and-autism-2/

https://www.psy-journal.com/article/S0165-1781(13)00737-3/fulltext

https://www.hindawi.com/journals/omcl/2017/5828056/abs/

These metabollic issues can be caused by vaccine injury and glyphosate.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028461/

https://www.ncbi.nlm.nih.gov/pubmed/17127302

https://www.westonaprice.org/health-topics/environmental-toxins/violent-behavior-a-solution-in-plain-sight/

https://www.tandfonline.com/doi/abs/10.1080/1028415X.2017.1423268?journalCode=ynns20

Low CoQ10 can contribute but under certain circumstances it could increase oxidative stress making things worse. So I would so address the issues causing the low CoQ10 before taking it.

https://www.ncbi.nlm.nih.gov/pubmed/20010493

Mast cell activation can cause a number of illnesses.

http://www.mastcellaware.com/mast-cells/related-conditions.html

https://www.prohealth.com/library/study-shows-that-mast-cell-activation-a-disorder-common-in-lyme-disease-causes-depression-5478

http://planetthrive.com/2010/12/the-alkaline-brain/

Spinal fluid leak can be caused by fluoroquinolones or tick born illness.

http://spinalcsfleak.org/

Mercury can cause problems with the NMDA receptor. They claim it is not in vaccinations but that is a lie some still contain it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241260/

https://www.nature.com/articles/4001529

They try to blame genetics for mercuries effects on the NMDA receptor.

https://www.nature.com/articles/4001529

Serine helps.

https://pubs.acs.org/doi/10.1021/acs.jafc.7b04217

vitamin B6 helps by reducing brain inflammation.

http://www.hormonesmatter.com/reducing-brain-inflammation-vitamin-b6/

Ashwanga enhances memory through the NMDA receptor.

https://www.ncbi.nlm.nih.gov/pubmed/23711138

If the body is not producing enough endocanabinoids , phytocanabinoids my help.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342457/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877778/

Sarcosine helps with NMDA issues.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921092/

https://jamanetwork.com/journals/jamapsychiatry/fullarticle/209027

D3 also helps reduce psychosis through the NMDA receptor.

https://www.ncbi.nlm.nih.gov/pubmed/12842123

Those with anti-NMDA antibodies have been found to be low in vitamin D.

https://www.ncbi.nlm.nih.gov/pubmed/27836631

The NMDA receptors help regulate glucose homeostasis.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903398/

http://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(15)00248-9

Fasting reverses some aging in the brain through NMDA.

http://www.jneurosci.org/content/27/38/10185

PQQ helps with nuerotoxic injury.

https://www.ncbi.nlm.nih.gov/pubmed/1318959

https://michaelrucker.com/glutamate/pqq-glutamate-nitric-oxide-and-n-methyl-d-aspartic-acid-receptors/

Cat’s Claw helps with NMDA issues.

https://www.ncbi.nlm.nih.gov/pubmed/15531384?dopt=Abstract

Not sure what Acorus is but it helps with NMDA issues.

https://www.ncbi.nlm.nih.gov/pubmed/11253173?dopt=Abstract

Psychotria Colorata helps with NMDA issues and opioid addiction.

https://www.ncbi.nlm.nih.gov/pubmed/11417913

Huperzia serrata contains huperizine A which helps with alzheimer’s

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137276/

Aspertame an atrificial sweetener can cause damage to the NMDA receptors.

https://www.globalhealingcenter.com/natural-health/health-dangers-of-aspartame/

MSG also has a negative impact on the NMDA receptors.

https://www.researchgate.net/publication/303458692_The_effects_of_monosodium_glutamate_and_aspartame_on_rat_hippocampal_N-methyl-D-aspartate_receptor_subunits_and_oxidative_stress_biomarkers

Muscarinic

Muscarinic receptors are G-protein (molecular switches) coupled acetycholine receptors. They are found on the outer membrane of certain neurons and cells. There are five types of Muscarinic Acetylcholine receptors (mACHRs). M1-M5 , when the odd numbered receptors are stimulated they produce increased levels of cytoplasmic (material within a cell) calcium ions in the cell. The odd number receptors trigger synthesis of a chemical messenger IP3 (inositol triphosphate-a phytate) which releases intercellular calcium stores from certain calcium stores that have been sequestered away in the cell. The increased cellular calcium concentration will lead to increased NO production by nNOS and eNOS this can lead to high peroxynitrite levels.

Over stimulation of mACHRs from farm chemicals and many other toxins like heavy metals cause high acetycholine levels by inhibiting acetylcholesterase enzyme which breaks down acetylcholine. This causes high levels of acetycholine which causes the release of NO leading to the production of peroxynitrite. Excessive supplementation of DMAE or Centrophenoxine which has a DMAE component can result in elevated acetylcholine. This can also lead to excess inflammation throughout the body because it is involved in reducing inflammation.

High acetylcholine levels can cause anxiety and high risk taking behavior and mood swings.

http://www.pnas.org/content/103/13/5219

Scopolamine found in belladonna can inhibit muscarinic excitability.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285663/

Nutrients for the muscarinic receptors.https://ecommons.aku.edu/cgi/viewcontent.cgi?referer=https://swisscows.com/&httpsredir=1&article=1032&context=pakistan_fhs_mc_bbs

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1471-4159.2011.07616.x

Mugwort helps

https://ecommons.aku.edu/cgi/viewcontent.cgi?referer=https://swisscows.com/&httpsredir=1&article=1032&context=pakistan_fhs_mc_bbs

Tylenol autism.

https://vactruth.com/2016/06/25/acetaminophen-and-autism/

https://safeminds.org/news/data-points-acetaminophen-exposure-children-potentially-inducing-autism/

Psychological Stress or Trauma

Psychological stress or trauma causes high NO levels which can lead to high peroxynitrite levels which is very damaging to the brain and body. iNOS is upregulated in the lungs and liver during stress. High iNOS levels have been found to be common in post traumatic stress disorder and many illnesses involving chronic fatigue. iNOS is also unregulated during physical trauma which makes those who have been abused more susceptible to chronic fatigue disorders.

Vaccinations and NMDA

It is stated on many vaccine inserts that brain swelling is a side effect. Vaccinations have a dramatic impact on the NMDA and Muscarinic receptors causing the above mentioned things. If you look up the symptoms of autism you will see that brain swelling is the main symptom. But the pharmaceutical companies play the rename game. When people start figuring things out they will rename an illness. They now call it encephalopathy. They played this very game when people figured out that Gulf War Syndrome was caused by vaccinations. They now call it ASIA syndrome.

Aluminum is in vaccines.

https://www.frontiersin.org/articles/10.3389/fneur.2014.00212/full

https://www.ncbi.nlm.nih.gov/m/pubmed/6135334/

https://cdn2.hubspot.net/hubfs/519118/Content%20Offerings/Summary%20of%20Studies%20Featured%20in%20Vaccines%20and%20Autoimmunity%20.pdf

http://www.greenmedinfo.com/article/study-found-increased-asd-risk-among-children-whose-mothers-received-influenza

http://www.ageofautism.com/2010/05/peer-reviewed-papers-support-findings.html

https://bmcneurol.biomedcentral.com/articles/10.1186/1471-2377-11-149

https://arupconsult.com/content/n-methyl-d-aspartate-nmda-type-glutamate-receptor-autoantibody-disorders

https://link.springer.com/article/10.1007%2Fs12026-016-8855-1

http://circleofdocs.com/30-solid-scientific-studies-that-prove-vaccines-cause-autism/

https://medel-la-production.s3.amazonaws.com/uploads/attach_document/document_file/59725b7269702d07c0bf0000/Acute_Disseminated_Encephalomyelitis_After_Influenza_Vaccination.pdf

https://www.sciencedirect.com/science/article/pii/S0946672X17308763

https://jbiomedsci.biomedcentral.com/articles/10.1186/1423-0127-19-51

https://www.hindawi.com/journals/jt/2014/491316/

https://www.ncbi.nlm.nih.gov/pubmed/944354

https://www.ncbi.nlm.nih.gov/m/pubmed/24996055/

https://www.ncbi.nlm.nih.gov/pubmed/21058170

https://jamanetwork.com/journals/jamapediatrics/article-abstract/2617988

http://www.globalresearch.ca/mitochondrial-collateral-damage-thanks-to-big-pharma/5447650

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1112717/

https://www.ncbi.nlm.nih.gov/pubmed/15265850

http://www.ageofautism.com/2010/07/new-study-shows-vaccines-cause-brain-changes-found-in-autism.html

https://jamanetwork.com/journals/archneurpsyc/article-abstract/647602#nav

https://www.jocn-journal.com/article/S0967-5868(08)00189-6/fulltext

http://www.vaclib.org/links/jockslinks.htm

They claim mercury has been removed from vaccines but that is a lie because some still contain it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705731/

https://www.ncbi.nlm.nih.gov/pubmed/23843785

https://www.ncbi.nlm.nih.gov/pubmed/16870260

https://www.ncbi.nlm.nih.gov/pubmed/19357975

https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(13)70278-3/abstract

https://www.globalresearch.ca/big-pharma-prescribed-drugs-or-vaccine-induced-dementia-is-not-alzheimer/5628607

http://www.greatergoodmovie.org/learn-more/science/brain-inflammation-encephalitis-post-vaccination/

https://www.hopkinsmedicine.org/news/media/releases/brain_inflammation_a_hallmark_of_autism_large_scale_analysis_shows

https://www.ncbi.nlm.nih.gov/pubmed/22015705

https://www.mcleanhospital.org/news/mclean-hospital-neuroscientists-find-immune-system-newborns-may-affect-developing-brain

https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/2047-9158-3-16

https://www.ncbi.nlm.nih.gov/pubmed/21549155

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173748/

https://web.archive.org/web/20150210051051/http://www.ashotoftruth.org/history

Autoimmunity.

http://journals.sagepub.com/doi/abs/10.1177/0961203311429550?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

Toxins cause oxidative stress which leads to brain injury.

https://www.researchgate.net/figure/Methionine-synthase-links-oxidative-stress-to-epigenetic-regulation-Figure-4-shows-how_fig4_223971780

Nutrients that help.

http://www.mdpi.com/2072-6643/10/3/369

Saffron can help with the effects of these things.

https://www.sciencedirect.com/science/article/pii/S094471131400364X?via%3Dihub

https://www.ncbi.nlm.nih.gov/pubmed/21623535

Increasing Ghrelin may help.

https://www.selfhacked.com/blog/ghrelin-role-cognitive-gut-function-weight-inflammation-autoimmunity/

Melatonin helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1571800/

Fish oil helps.

https://draxe.com/fish-oil-benefits-health/

Removing aluminum from the brain.

http://realfarmacy.com/mineral-waters-remove-aluminum-from-brain/

Black Sativa helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642442/

Having pets helps.

https://www.nih.gov/news-events/news-releases/animals-presence-may-ease-social-anxiety-kids-autism

Corn silk helps but must be organic. The BT Toxin and glyphosate in GMOs have been shown to cause autism.

https://innovareacademics.in/journals/index.php/ijpps/article/view/6943

Anise oil helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416669/

orthosilicic acid may help or silica

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546016/

https://www.ncbi.nlm.nih.gov/pubmed/3743228

To increase my brain glycogen levels in the morning I started using maple syrup, honey or organic unsulfured blackstrap molasses.

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1471-4159.2004.02421.x

Luteolin helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490655/

Niacin may help.

http://blog.healthybynaturehwc.com/niacin-deficiency/#comment-1287

Wild violet helps with insomnia.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341349/

Some natural therapies that helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994794/

https://feingold.org/

Ebselem helps by reducing oxidative stress.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759215/

Ferulic Acid found in wheat bran and angelica helps.

https://www.sciencedirect.com/science/article/abs/pii/S0031938416308691

Sulfur and autism.

https://www.blants.com.au/autism.html

Flaxseed increases MAO release which may help.

http://journals.sagepub.com/doi/abs/10.1177/0960327115571765

Tryptophan my help with some but there are certain metabolic issues this could make worse.

https://www.ncbi.nlm.nih.gov/pubmed/11336160

St. Johnswort may help.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736901/

Plants that may help.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597072/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452207/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210916/

Plants that help reduce acetycholine.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518125/

Honeysuckle may help.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492671/

Metallothein helps.

https://metabolichealing.com/metallothionein-forgotten-antioxidant-missing-puzzle-piece-for-alzheimers-leaky-gut/

Lionsmane mushroom helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583117/

Gingko really helped me but the first couple of times I took it, it gave me a headache. It you take it for too long it can damage the liver. But certain vitamins can do that.

https://www.jstage.jst.go.jp/article/bpb/37/2/37_b13-00378/_article

Some herbs that helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459457/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993511/

http://www.encognitive.com/node/6310

Palmitoylethanolamide helps.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531370/

Baicalein found in sculletaria, fleabane and plantain herb helps. Helped me a lot.

https://www.ncbi.nlm.nih.gov/pubmed/27518088

Hydroxocolbalamin may help.

https://www.prohealth.com/library/the-brain-boosting-and-fatigue-fighting-b-12-26949

Diet for those with phenylketonuria. I fixed mine.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750587/

Thymus found in savory, juniper berries, thyme, black sativa and bergamot will help.

https://www.ncbi.nlm.nih.gov/pubmed/24814387

Passion flower helps but I have seen studies that make me question the safety of it’s long term use. I would only use when needed.

https://www.ncbi.nlm.nih.gov/pubmed/27693740

Self heal helps.

https://onlinelibrary.wiley.com/doi/10.1002/ptr.4929

Pyrroluria is a symptom of porphyria. This will help the pyrroluria part of the symptoms.

https://nutrientpower.wordpress.com/pyrroluria/

For those who have symptoms severe enough to cause convulsions these herbs have been researched.

http://www.eurekaselect.com/152566/article

Tips for reducing brain inflammaton.

http://www.hormonesmatter.com/reducing-brain-inflammation-vitamin-b6/

Rooibos helped me.

https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.201300463

Roseroot helps. Actually I looked at the phytochemicals of the whole plant and they are pretty much the same throughout the plant.

https://www.medicalnewstoday.com/articles/291596.php

Quiet time helps.

https://www.lifehack.org/377243/science-says-silence-much-more-important-our-brains-than-thought?ref=facebook

Serrapeptase and nattokinase helps but very high doses can have serious negative health effects.

http://journals.sagepub.com/doi/abs/10.1177/0960327112467040?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed

For better sleep.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008810/

Pyrroloquinoline Quinone helped me a lot with healing.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303106/

N-acetylcysteine helped me.

https://www.optimallivingdynamics.com/blog/the-powerful-antioxidant-proven-to-treat-6-mental-illnesses

Hops was another one that helped me a lot. It has a cannabinoid similar to THC, I react bad to THC but not to hops.

https://akademiai.com/doi/abs/10.1556/APhysiol.99.2012.2.6?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dpubmed

God info on healing nerves and the brain.

https://www.selfhacked.com/blog/myelin/

Good info on healing children with autism.

http://www.healourlittleones.com/?p=837

Reducing endothelins can helps, this would also help with high blood pressure.

https://www.selfhacked.com/blog/endothelins/?utm_source=ActiveCampaign&utm_medium=email&utm_content=The+Latest+From+SelfHacked&utm_campaign=Jan282018+Newsletter

Cut toxic people out of your life. If they cared they would not be so toxic.

https://themindsjournal.com/why-its-okay-to-cut-toxic-family-members-out-of-your-life/

Thiamine deficiency can cause many health problems.

https://www.livescience.com/51721-vitamin-b1-thiamine.html

Those who are G6PD deficiency or metabolic issues especially porphyria or sulfation issues need to address them because the foods that contain thiamine could make them ill if they do not. They may have to supplement until they have addressed them.

https://draxe.com/thiamine-foods/

https://www.livescience.com/51721-vitamin-b1-thiamine.html

Folic Acid is man made and not good for the body and can cause problems.

https://www.drbenlynch.com/resource/why-you-should-stop-taking-folic-acid/

http://blog.naturalhealthyconcepts.com/2015/05/13/the-difference-between-folate-folinic-acid-and-folic-acid/

https://www.thehealthyhomeeconomist.com/folic-acid-making-us-sick/

https://www.globalhealingcenter.com/natural-health/difference-between-folate-and-folic-acid/

Folic acid has been linked to cancer. Folate has not.

https://breastcancerconqueror.com/the-hidden-dangers-folic-acid-vs-folate/

the gut and cholestokinin

http://www.yourhormones.info/hormones/cholecystokinin/

https://www.selfhacked.com/blog/good-bad-effects-cck/

Trypsin inhibitors increase cholecystokinin.

https://naldc.nal.usda.gov/download/26115/PDF

Things that raise GABA like , mugwort, wormwood and rooibos reduces cholecystokinin levels. High estrogen levels cause high cholecystokinin levels. High dopamine levels increases cholecystokinin. High levels of cholecystokinin causes glutamate toxicity and NMDA toxicity.

https://www.acnp.org/g4/GN401000056/CH056.html

Potatoes increase cholecystokinin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033477/

If not addressed it leads to autism.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628252/

 

Meditation now called nuero feedback can help heal the brain.

https://www.frontiersin.org/articles/10.3389/fpsyg.2013.00688/full

https://www.selfhacked.com/blog/neurofeedback/?mpweb=1367-178-19862

There are various meditation technique depending on the desired outcome.

https://www.researchgate.net/publication/41486162_Focused_attention_open_monitoring_and_automatic_self-transcending_Categories_to_organize_meditations_from_Vedic_Buddhist_and_Chinese_traditions._Consciousness_and_Cognition_19(4)_1110-1118

https://www.brainsinternational.com/default/assets/File/Phenotype_%20Johnstone,%20et%20al.pdf

Those who meditate have higher cognitive function and less stress.

https://www.goalcast.com/2017/06/20/healing-power-meditation-brain-health/

Meditation even helps with inflammatory bowel disease. It can turn bad genes off.

https://news.harvard.edu/gazette/story/2015/05/meditation-may-relieve-ibs-and-ibd/

https://www.brainline.org/article/role-mindfulness-meditation-and-prayer-after-brain-injury

Endotoxemia or Sepsis

This is not medical advice and should not be taken as such. I post this for educational and informational purposes.

Because most allopathic medical treatment is not based valid scientific research you need to be your own advocate and do your research. Allopathic medicine is usually about 50 years behind the science. So in order to be healthier you will need to educate yourself and become an advocate for your own health . It takes a lot of self discipline and persistence.

I did a post on Jarisch-Herxheimer reaction. Herxing is a symptom of the die off from an infection. In this post I am going to show what all is going on as a pathogens die off. One of the major toxins is endotoxins they also secrete excitoxins. They cause most of the damage from dying pathogens. The presence of endotoxins in the blood is called endotoxemia. You do not have to be treated with antibiotics to experience it. The body fighting infection can raise endotoxins in the blood. Many now days most likely are carrying and infection of some type and do not know it because vaccinations have been found to be contaminated with mycoplasma and most have been vaccinated. Mycoplasmas can live in the body for many years. Endotoxins are usually connected to bacterial infections. Endotoxins can be released when fungal infections die off also. When Candida is in pathogenic form it will release endotoxins when it dies off. Inflammation is the main culprit in endotoxemia. It can inhibit many metabolic pathways, disable the immune system. As a matter of fact it is one of the main tactics used by HIV and Lyme to disable the immune system. It will take a while but I will try to do post on methods used to address the many health issues caused by endotoxemia.

Now GMOs and the farm chemicals used in agriculture can cause the very same things but have to be dealt with somewhat differently. Our food supply has been found to contain high levels of farm chemicals and the BT Toxin in Genetically Modified foods has been found to cause the body to react the same way it would if you had food poisoning. That is why many feel like they have a brick in their stomach after eating. So you can experience sepsis which would resemble endotoxemia but need to address it somewhat differently. If time permits I will address sepsis caused by things like these. Imagine if you are dealing with an infection which many infections can persist for years without major symptoms and now you are dealing with sepsis from farm chemicals. Now you have become Synergistically Ill. Vaccine injury is a result of a synergistic effect of the bodies reactions to the pathogen in the vaccine and the toxins so it would be a synergistic type illness. Just just as we would need to learn how farm toxins and environmental toxins contributed synergistically to make someone ill and how those toxins effected the body would need to be researched and addressed so would the toxins in the vaccine that caused the injury and how the toxins in them have effected the body.

Inflammation causes changes in pathways involved in oxidative stress, fatty acid metabolism, the bodies system for healing and protecting itself, and the coagulation system of the blood. This can result in a variety of illnesses and each is effected differently. In some instances in the elderly instead of having excess inflammation their inflammatory response may be inhibited which can prevent the body from healing and protecting itself. Once Lyme sets off an inflammatory response it will use this tactic to protect itself from an immune response. Lyme sets off an inflammatory response to initially evade the immune system. This causes the body to unleash an all out attack but Lyme is prepared for such an attack and once established it will start doing the opposite and start inhibiting inflammation to help stealth itself from the bodies immune system. Drugs are another source of synergistic effects that can cause a synergistic effect of sepsis and side effects that cause injury to the body which complicates matters. Many believe they are only dealing with sepsis but often times they are dealing with the synergistic effects of sepsis and something else in their environment. Fluroquinolones are known to cause major damage to the body and induce sepsis causing a synergistic effect.

In order to detox the endotoxins we must focus on controlling inflammation, we need inflammation to heal so homeostasis is the goal. We need inflammation to heal so if we suppress it too much then we will prevent ourselves from healing. We need to reduce inflammation but not prevent it entirely.

So we must address the issues the inflammation and high toxin levels have caused, thing like inhibited glucuronidation, sulfation issues, porphyria, phenylketonuria, and many other metabolic issues that can occur from chronic illness. Not only that but many other things need to be addressed our detox enzymes can be inhibited or depleted and would need to be addressed. This can be done with proper nutritional support and diet adjustments to prevent feeding the problems and making them worse. For example cutting processed sugars especially fructose from the diet. This does not mean cutting the fruits that contain sugars in them because they are actually needed by the body and are different because of the way they enter the body and are used by the body. I have posted on how I dealt with some of these issues already.

The majority of the medical community seem to be unaware of endotoxemia and do not seem to be able to identify or deal with it.

https://www.jillcarnahan.com/2018/04/30/toxic-overload-from-within-metabolic-endotoxemia/

http://blog.probacto.com/everything-you-need-to-know-about-herxheimer-candida-die-off/

http://textbookofbacteriology.net/endotoxin.html

https://www.sciencedirect.com/science/article/pii/002248049290125J

Inflammation is the major cause of damage from endotoxemia.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923340/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373965/

Endotoxemia can result in septic shock which results in permanent damage and can be life threatoning.

https://www.sciencedirect.com/science/article/pii/S0012369216302665

It increases your risk of mortality.

https://www.ncbi.nlm.nih.gov/pubmed/26166090

Hearing loss

https://www.ncbi.nlm.nih.gov/pubmed/26223301

Causes many types of illnesses including diabetes and obesity.

http://jme.endocrinology-journals.org/content/51/2/R51.full

It can result in liver damage.

https://www.ncbi.nlm.nih.gov/pubmed/24475189

Endotoxemia can result in excessive blood clotting.

http://www.bloodjournal.org/content/128/22/3725?sso-checked=true

https://www.ncbi.nlm.nih.gov/pubmed/29734352

Can cause damages to the lungs.

https://www.jci.org/articles/view/94495

Endotoxemia can make us hyperglycemic.

https://www.ncbi.nlm.nih.gov/pubmed/29778648

I have found this to be very common in those with endotoxemia. Bile flow has been obstructed from the inflammation. This results in effects on the whole body. It is why we must work on getting inflammation down when suffering from endotoxemia. Inflammation is the major cause of the damage to our bodies.

https://www.ncbi.nlm.nih.gov/pubmed/29907203

Many develop phenylketonuria when ill. It must be addressed because phenylalanine is used to protect the brain from damage.

https://www.ncbi.nlm.nih.gov/pubmed/28795486

Endotoxemia can damage the heart of not addressed.

https://www.ncbi.nlm.nih.gov/pubmed/29465314

How our bodies respond to the inflammation is key to whether we heal, live or become damaged. Metabolic issues contribute to inflammation and is the reason they must be addressed for us to minimize the damage and even to survive.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383069/

This was the hardest part to deal with for me. Our diaphragms can become pretty much paralyzed. When I told my Lyme Literate Medical Doctor that sometimes I struggle to breath and had to force my diaphragm to work he laughed at me. I have come to the conclusion that LLMDs are a part of the fake allopathic medicine. Most allopathic medical treatment is not backed by science.

https://www.ncbi.nlm.nih.gov/pubmed/29925937

Many develop high acetycholine levels because endotoxins can inhibit acetylcholesterase which breaks down acetylcholine. It is very important to address this because not only will this cause mental issues like anxiety it can also result in a higher rate of mortality. This is why it is very important to address the things causing the inflammation.

https://www.ncbi.nlm.nih.gov/pubmed/29853783

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949165/

The saddest part of it all is the medical community is still struggling on how to identify sepsis. What I am finding is allopathic medicine is usually decades behind the science. For example all research concerning Lyme disease decades ago was proven to have been falsified. There is newer real research on Lyme disease and it’s treatment but allopathic medicine is still relying on the falsified studies from decades ago in their decision making on patients care in tick born illness.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877904/

Omega 3 fatty acids help but if you have porphyria you must address it before you will be able to take oils.

https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-10-6

Because endotoxins cause inflammation we must reduce inflammation.

http://www.mdpi.com/2075-4663/6/1/12

HDL is needed to protect us and can become low during endotoxemia.

https://proteomesci.biomedcentral.com/articles/10.1186/1477-5956-9-34