Benefits of astragalus.

Written by Lee Stevenson, sorry I am a lousy editor.

This is not medical advice I have written this for educational purposes. If you are ill please seek the aid of a qualified and experienced functional medicine practitioner.

Astragalus Radix

Astragalus has been shown to help improve diabetes by improving bile properties. Which improves the production of glycogen in the liver and improves glucose uptake by cells. This could also help to prevent obesity.

Astragalus inhibits TH2 and TNF-a. TH2 in excess can cause a rash over the whole body. NfxkB is overexpressed during infection. Astragalus inhibits the negative effects of endotoxins during infection. It does seem to balance the immune system by increasing T regulatory cells which would improve over all immune function.

This herb is better for those who have an inhibited immune system but those with interstitial cystitis and Crohn’s may want to avoid it because it increases expression of TLR4 which does help fight infection but can cause inflammation and it is over expressed in IC and Crohn’s. This does give astragalus potent antiviral properties.

Astragalus is potent for reducing oxidative stress. It also improves heart function and prevents bone loss and improve collagen health.

It stimulates PPARa which would activate beta oxidation which prevents diabetes, insulin resistance , glucose intolerance and obesity. It also inhibits endoplasmic reticulum stress which would prevent mitochondrial dysfunction.

It prevents excess mucus production in the lungs. It also prevents lung injury while promoting healing in the lungs.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8152973/

https://pubmed.ncbi.nlm.nih.gov/33953787/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270929/

https://pubmed.ncbi.nlm.nih.gov/26343107/

https://pubmed.ncbi.nlm.nih.gov/29044703/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470777/

https://pubmed.ncbi.nlm.nih.gov/32089240/

https://pubmed.ncbi.nlm.nih.gov/29170045/

Benefits of Rehmannia.

Written by Lee Stevenson, sorry I am a lousy editor

This is not medical advice I have written this for educational purposes. If you are ill please seek the aid of a qualified and experienced functional medicine practitioner.

Chinese foxglove (Rehmannia glutinosa)

Rehmania helps to prevent insulin resistance which causes type 2 diabetes.

Rehmannia is neuroprotective so prevents nerve damage and improves brain function. Rehmannia also protects the brain from glutamate toxicity. Because rehmannia prevents glutamate toxicity it would also help to reduce convulsions because it would improve the function of the GABA receptors.

Rehmannia protects the body from the negative effects of endotoxins. It has potent antioxidant and anti-inflammatory properties.

Rehmannia is best taken at night because it has sedative effects.

Rehmannia my help prevent osteoporosis.

Rehmannia improves mitochondrial function which increases ATP levels. This is also why rehmannia increases exercise endurance. Rehmannia also prevents muscle atrophy. This would also prevent obesity and diabetes but when first taken it can cause hypoglycemia. I would never take this excessively or in high doses.

Rehmannia my prevent fibrosis in the lungs.

Rehmannia does help to prevent type 2 diabetes but can cause hypoglycemia. Rehmannia also improves the health of the pancreas.

Rehmannia helps to prevent some of the effects of aging by turning on the antiaging genes. It also stimulate autophagy which helps to clear infection, clean junk out of the cells and improve mitochondria function which would help prevent obesity and diabetes.

Ok this study has to be read separately. The reason I say this is because it helps to prevent Parkinson’s. It does it by inhibiting the very things that herpes viruses use to infect cells. Is Parkinson’s actually an infection with a herpes virus? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448250/

https://pubmed.ncbi.nlm.nih.gov/29284152/

https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.12200

https://pubmed.ncbi.nlm.nih.gov/28111216/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607830/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128353/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718720/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320869/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388079/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874442/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059811/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067417/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864906/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878558/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139823/

Benefits of nicatinomide.

Written by Lee Stevenson, sorry I am a lousy editor.

This is not medical advice I am writing this for educational purposes. If you are ill please seek the aid of a qualified and experienced functional medicine practitioner.

Nicatinomide

Nicatinomide increase NAD+ which is needed by every cell in the body. As we age or get chronically ill we lose the ability to produce NAD+ in adequate amounts. Nicatinomide is a form of niacin (B3). Nicatinomide has been shown to reverse many of the effects of chronic illness and aging. It is needed for glycolysis which is involved in burning fats stored in the liver to produce glucose for the body. NAD+ is also involved in fatty acid oxidation which is the bodies way of burning fats to produce glucose for the body. If glycolysis is inhibited a person will develop fatty liver disease, if beta oxidation is inhibited a person will develop diabetes and hypoglycemia. NAD+ is involved in the proper function of all the antiaging genes. NAD+ is also involved in many of the function that protect us from infections including viral infection. So nicotinamide helps to prevent diabetes, obesity and many age related diseases.

Nicatinomide helps to prevent neurological damage and damage to the brain and improves brain function. It improves learning and memory. It has been found to help prevent depression. It also prevents damage to the brain by improve the function of many pathways in the body preventing toxic metabolites from being produced.

Nicatinomide improves function of the antioxidant system which would protect DNA. Nicatinomide also improve DNA repair. Nicatinomide also improve RNA processing and protects it from premature degradation.

Nicatinomide improves indurance and stamina by improving the bodies ability to burn fats for energy. Fat is the bodies main source of energy. When it cannot burn fat for energy and has to rely on glucose a person will develop frequent episodes of hypoglycemia. With hypoglycemia a person may experience headaches, lightheadedness, dizziness, heart palpitation, feeling flush or hot and may even sweat severely. The reason for the frequent boughts of hypoglycemia is that glucose is rapidly consumed for food and the glucose from fats is released slowly which keeps the glucose levels stable in the body.

Nicatinomide helps to prevent autoimmunity by keeping the immune system balanced. It also improves the ability of the immune system to respond to infection. It helps to prevent many types of viral infection including herpes, corona, the flu and many others.

Nicatinomide also improve the function of the circadian rhythm our bodies natural clock.

Nicatinomide also improves function of the citric acid cycle.

Because NAD+ reduces oxidative stress and inflammation it also helps to prevent cardiovascular disease.

Nicatinomide also improves muscle endurance and strength. It also prevents muscle degeneration.

NAD+ also helps prevent the build of of fibrotic tissue in the body which can cause organ failure so it helps to protect the organs.

It should be taken with food because if taken on an empty stomach a person will experience nausea, fatigue, headaches, diarrhea, stomach discomfort and indigestion. It should not cause flushing like niacin does. From what I could tell a person can take up to 1000 to 2000 mg daily but I would research which is the best amount to take. Excess nicotinamide consumption can inhibit growth of new cartilage and it also inhibits the genes that protect the body from cancer. So once the health issue is addressed that required the consumption of nicotinamide I would recommend pulsing it or discontinuing it’s use if it is no longer needed. I would not take super high doses of nicatinomide.

Nicotinamide has been shown to reduce the occurrence of acne.

https://www.healthline.com/nutrition/nicotinamide-riboside#risks-and-side-effects

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795269/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539288/

https://pubmed.ncbi.nlm.nih.gov/27508874/

https://pubmed.ncbi.nlm.nih.gov/34179114/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277745/

Benefits of black cummin.

Written by Lee Stevenson, sorry I am a lousy editor.

This is not medical advice I am writing this for educational purposes. If you are ill please seek the aid of a functional medicine practitioner.

Black seed (Nigella sativa)

Also known as black caraway, or black cumin. It is more potent against many super bugs then antibiotics. Black seed also has potent antifungal properites. Black seed also has some antiviral properties. This effect is most likely because black seed increases white blood cells. This is also why black seed has been found to fight many types of cancer.

Black seed should be used at night because it can cause drowsiness. Black seed increases serotonin and GABA levels which are our feel good hormones and they help improve sleep quality.

Black seed has very potent anti-inflammatory and antioxidant properties. This is most likely why black seed has been shown to improve liver function.

It activates AMPK which helps prevent metabolic disease, diabetes and obesity. Black seed has been shown to normalize insulin and glucose levels.

Back seed is cardio protective. It increases Nitric oxide levels, reduces almost all inflammatory cytokines that are found in autoimmunity, sepsis and inflammatory diseases. It decreases triglyceride levels in the body which is an indication the body is healing. Black seed oil also things the blood.

Black seed is neuroprotective and improves memory and learning. Blood seed reduces the occurrence of seizures.

Black seed improves thyroid function.

Black seed reduces histamines which would help with asthma and allergies.

Black seed helps with osteoarthritis it reduces joint inflammation and injury. Black seed also reduces sensitivity to pain.

Black seed prevents inflammation and ulcers in the digestive tract. It also can help to prevent necrosis in the digestive tract, but if taken in high amounts it can irritate the gut.

In super high doses black seed can damage the liver and kidneys but that is true about most things including vitamins. It can also cause rashes in some people, most likely those with high white blood cell levels. Black seed slows down uterine contractions so should not be taken by women who are pregnant when they are ready to conceive. Taking high dose black seed can cause drowsiness and fatigue. If taken in excess black seed can cause nasal dryness and diarrhea.

https://www.researchgate.net/publication/36448004_Antimicrobial_activity_of_Nigella_sativa_Linn_seed_oil_against_multi-drug_resistant_bacteria_from_clinical_isolates

https://pubmed.ncbi.nlm.nih.gov/23543440/

https://pubmed.ncbi.nlm.nih.gov/33140312/

https://www.jofem.org/index.php/jofem/article/viewArticle/15/15

https://pubmed.ncbi.nlm.nih.gov/23777875/

https://pubmed.ncbi.nlm.nih.gov/33981219/

https://www.ajol.info/index.php/ejbmb/article/view/60802

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642442/

Benefits of astaxanthin.

Written by Lee Stevenson, sorry I am a lousy editor.

This is not medical advice, I have written this for educational purposes. If you are ill please seek the aid of a qualified and experienced functional medicine practitioner.

You have to be careful buying astaxanthin there is synthetic astaxanthin and it can cause many health problems. Get it from food sources like eating salmon or krill oil or only use supplements that contain astaxanthin acquired from natural sources. Astaxanthin has a pretty good safety record. Astaxanthin is better absorbed when taken with an oil.

Astaxanthin is one of the most powerful antioxidants. Because of it’s potent antioxidant and anti-inflammatory properties at can reverse some of the effects of aging and has been found to improve eyesight. It has more potent anti-inflammatory properties then steroids. Astaxanthin prevents the negative effects of blue light from cell phone and computer screens.

Astaxanthin reduces wrinkling and improves the health of the skin. It prevents the harmful effects of UV light to the skin.

Astaxanthin reduces cognitive decline, improves BDNF which increases brain plasticity which means it will improve cognition, brain function, and the ability to retain memories. It improves brain blood flow and prevent damage from oxygen deprivation in the brain.

Astaxanthin improves blood flow. Prevent cardiovascular disease, protects the heart from damage and improves blood pressure.

Astaxanthin improves mitochondrial function which would improve the health of the whole body. This would also improve the ability of mitochondria to break down fat to use for energy and improve the mitochondrias ability to produce ATP.

Astaxanthin improves muscle endurance and recovery during exercise. This may be because astaxanthin helps improve insulin and glucose balance.

Astaxanthin has been found to prevent and even reverse many types of cancer. Astaxanthin can also prevent the negative effects physical trauma has on the body.

Astaxanthin can prevent fibrosis in the body which can cause fatty liver and dementia type diseases like Alzheimer. It also prevents liver damage by improving bile duct function. It prevents fatty liver disease from improving the bodies ability to break down and burn fat for energy.

Infection and toxins can cause excess inflammation which can cause loss of smell and hearing. Astaxanthin help prevent loss of hearing and smell from excess oxidative stress and inflammation.

During infections, vaccine injury, toxins like glyphosate in our foods and environment can cause excess inflammation and oxidative stress. This causes tissue ischemia, astaxanthin prevents the damage when that occurs. Those prevention is the best medicine we cannot control everything in our environment. It also help to prevent neurological disease. Astaxanthin actually improves the function of stem cells.

Astaxanthin turns on many of the antiaging genes which are inhibited by Covid and herpes.

Endotoxins and inflammation can cause tryptophan metabolism to shunt and produce toxic metabolites that cause dementia and depression. Astaxanthin prevents this from occurring. It also increases the microbes in the gut that could cause bad tryptophan metabolites to be formed and increases the microbes that reduces inflammation. Astaxanthin helps restore gut immune homeostasis.

There is a reason flamingos are pink if you do not want your skin or eyes to be pink do not consume excessive amounts of astaxanthin. It is what causes flamingos to be pink. Excess astaxanthin consumption can cause low blood pressure. It can also cause excess hair growth. Excess astaxanthin consumption can cause low calcium levels. Astaxantin increases progesterone in cows so may have this effect in humans though I have found no research to support that idea.

I can tell you from personal experience of people who have taken it. It dramatically decreases joint pain. If taken in high dose it caused headaches. Those who took high doses also experienced acid reflux. I do not recommend high dose astaxanthin. Many complain it messed with their hormones. Many other said it got rid of their acne so I suspect it increase their progesterone levels. It does seem to restore hormone balance and until the body gets used to the new hormone levels a person may feel bad.

https://therestored.com/blogs/nutrition/sustainable-astaxanthin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293384/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988001/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696511/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927222/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401277/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8065559/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527225/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836186/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677382/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878783/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551886/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421950/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680436/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566765/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139465/

https://academic.oup.com/jn/article/150/10/2687/5894073

https://journals.sagepub.com/doi/10.1177/1535370218763760

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487791/

https://www.amymyersmd.com/article/hormone-balance-eyesight/

Benefits of chlorophyll.

Written by Lee Stevenson, sorry I am a lousy editor.

This is not medical advice I have written this for educational purposes. If you are ill please seek the aid of a qualified and experienced functional medicine practitioner.

You can get it powdered or in liquid form. I have found the liquid form worked best for me. I got much quicker and more positive results. Chlorophyll has a very good safety record and is non toxic. Chlorophyll blocks the uptake mold toxins into cells. It has very potent antioxidant properties so prevents DNA damage. We have enzymes in the body that can activate procarcinogenic toxins. Chlorophyll blocks those enzymes from activating those toxins so preventing the possibility of them inducing cancer. It has been found to block ribonuclioside reductase activity which has been found to prevent certain types of intestinal cancer and to actually cause cell death of the cancer. Chlorophyll speeds up wound healing. It prevents the growth of bacteria that causes bad breath. Chlorophyll speeds up metabolism which could help with weight loss. Those who are obese experience frequent episodes of hypoglycemia (low blood glucose levels), liquid chlorophyll has been shown to prevent this from happening. It helps to turn off inflammation in the body.

Chlorophyll has been found to be effective against many types of cancer cells. Chlorophyll reduces inflammatory microbes in the gut and increase ones that reduce inflammation which would farther help to reduce the risk of cancer. Chlorophyll also prevents cancer by speeding up the degradation of carcinogenic substances in the body. Because chlorophyll prevents free radicals from being produced it would also prevent types of cancer caused by excess oxidative stress.

Because clorophyll reduces inflammatory cytokines including IL-6 which contributes to the lymphopenia that has caused some to die when contracting Covid it would prevent the detrimental effects of Covid if someone contracted it. Studies have shown at least 95% of the people who contract Covid show no symptoms it is better to be safe then sorry.

High TMAU levels have been linked to cardiovascular disease. It can cause a persons body and urine to smell like fish. Liquid chlorophyll and activated charcoal reduces TMAU levels. TMAU has been linked to diabetes, obesity and cardiovascular disease. It also reduces ammonia levels in the body. High ammonia causes glutamate toxicity in the brain which can cause autism and seizures.

One of the most interesting things about chlorophyll is the body can capture photoelectric energy from chlorophyll to produce ATP so it helps improve ATP levels. Because of this chlorophyll along with light therapy can help to prevent diabetes.

One of the side effects of chlorophyll it can make the poop greener. Also to make sure copper and zinc is balanced a person should take zinc when taking chlorophyll.

https://pubmed.ncbi.nlm.nih.gov/23632035/

https://pubmed.ncbi.nlm.nih.gov/32550209/

https://pubmed.ncbi.nlm.nih.gov/22038065/

Chlorophyll Benefits: The Top Detoxifying Plant Pigment

https://pubmed.ncbi.nlm.nih.gov/20163913/

https://pubmed.ncbi.nlm.nih.gov/30564133/

https://pubmed.ncbi.nlm.nih.gov/33777973/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7994343/

https://pubmed.ncbi.nlm.nih.gov/30057678/

https://pubmed.ncbi.nlm.nih.gov/33676582/

https://pubmed.ncbi.nlm.nih.gov/7518046/

https://pubmed.ncbi.nlm.nih.gov/11767414/

https://pubmed.ncbi.nlm.nih.gov/24385363/

https://pubmed.ncbi.nlm.nih.gov/15110092/

https://pubmed.ncbi.nlm.nih.gov/1903094/

https://pubmed.ncbi.nlm.nih.gov/7805041/

https://pubmed.ncbi.nlm.nih.gov/11724948/

https://pubmed.ncbi.nlm.nih.gov/15043988/

https://journals.biologists.com/jcs/article/127/2/388/54610/Light-harvesting-chlorophyll-pigments-enable

https://pubmed.ncbi.nlm.nih.gov/27731322/

https://pubmed.ncbi.nlm.nih.gov/31859908/

https://pubmed.ncbi.nlm.nih.gov/32526968/

Benefits of red sage.

Written by Lee Stevenson

This is not medical advice I am writing this for educational purposes. If you are ill place seek the aid of a qualified and experienced functional medicine practitioner.

Red Sage (Salvia miltiorrhiza)

In chinese medicine it is referred to as Danshen. Red sage improve cardiovascular health and has been shown to prevent strokes. Red sage has potent antioxidant properties. It also has potent anti-inflammatory properties. Because of red sage antioxidant and anti-inflammatory properties it helps to prevent fibrotic diseases like cirrhosis of the liver and Alzheimers disease. Though I have found no studies to support this statement I believe it would help with interstitial cystitis and inflammatory bowel diseases because it inhibits NLRP3 which is over expressed in those diseases. Red sage prevents diabetes induced eye injury and vision loss.

Red Sage improves brain function and cognition. It does thin the blood and prevents blood clotting. Most message boards that I have read on people who used it recommended only taking it for a month and then taking a one week break. Red Sage prevents high blood pressure by increasing nitric oxide levels. Nitric oxide is also one of the most potent antivirals used by the body. Because red sage improves blood flow and increases nitric oxide it prevents ischemia (tissue damage from inhibited blood flow).

Red Sage inhibits NADPH oxidase which is upregulate in inflammatory , and autoimmune diseases it inhibits beta oxidation and increases oxidative stress. Inhibiting NADPH oxidase would increase fat burning in the body and decrease oxidative stress. In order for that to occur mitochondrial respiration would have to increase so it would be safe to assume it improves mitochondrial respiration.

Nrf2 is the master regulator of the antioxidant system. Red sage is a potent Nrf2 activator which would increase antioxidant enzymes in the body.

Red sage increases mitophagy which is inhibited by RNA viruses like the herpes viruses. It also prevents autoimmunity by decreasing IgE levels which would prevent excess mast cell degranulation which would decrease histamines preventing and allergic response. It would also prevent over expreassion of TH2 immune response.

Red sage reduces oxalate levels in the body.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885196/

https://pubmed.ncbi.nlm.nih.gov/18361734/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7478559/

https://pubmed.ncbi.nlm.nih.gov/29212498/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610889/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421141/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193940/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167655/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646978/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555792/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360890/

https://www.hindawi.com/journals/ecam/2019/1408979/

Benefits of burdock root.

Written by Lee Stevenson , sorry I am a lousy editor.

I have written this for educational purposes , this is not medical advice. If you are ill seek the aid of a qualified and experienced functional medicine practitioner.

Burdock root (Arctium spp)

Burdock root has very potent antioxidant properties. Burdock root increases mitochondrial respiration which would prevent diabetes, glucose intolerance and obesity. It contains B-sitosterol which prevents diabetes. B-sitosterol has sedative effects so burdock root should be used at night. Burdock root prevents lung fibrosis. Burdock root improves memory in those with Alzheimer’s . Burdock root has potent antioxidant properties. Burdock root inhibits the inflammatory cytokines that cause autoimmunity and sepsis. It inhibits the effects of endotoxins on the body. Burdock root reverses aging in the skin. Burdock root inhibits blood clotting.. Burdock root is neuroprotective. It reverses some of the effects of Alzheimers. It helps prevent lung fibrosis from it’s anti-inflammatory and antioxidant properties. Burdock root increases fat burning in the body. Burdock protects the body and detoxes it of cadmium and mercury. Burdock root has potent antifunfal and antiviral properties. It inhibits RNA viruses including herpes viruses . Burdock inhibits mast cell degranulation which would reduce histamines. Burdock root helps to prevent anaphylaxis. Burdock root help to prevent leptin resistance which can cause obesity. Burdock increases exercise performance and endurance. Burdock root increases biogenesis which increases fat burning and increase ATP levels which would reduce fatigue. Burdock root helps to reduce ammonia levels in the body. Burdock root also prevents urinary tract infections. I could go on about the benefits but I think I painted a clear picture of the health benefits.

As for side effects I could not find studies that tested for that but the root is eaten for food in many cultures so I would say it’s safety has been tested.

https://mybiohack.com/blog/burdock-arctium-lappa-arctigenin-arctiin

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073957/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943639/

https://www.sciencedirect.com/science/article/pii/S0753332220308957

https://www.frontiersin.org/articles/10.3389/fphar.2017.00697/full

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629911/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8327179/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619735/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772408/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8313330/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132581/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645604/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011280/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011149/

https://pubmed.ncbi.nlm.nih.gov/28780467/

https://pubmed.ncbi.nlm.nih.gov/28976750/

https://pubmed.ncbi.nlm.nih.gov/28976750/

https://pubmed.ncbi.nlm.nih.gov/20607501/

https://pubmed.ncbi.nlm.nih.gov/24933284/

https://pubmed.ncbi.nlm.nih.gov/31338098/

https://pubmed.ncbi.nlm.nih.gov/22753037/

https://pubmed.ncbi.nlm.nih.gov/32297701/

https://pubmed.ncbi.nlm.nih.gov/28348972/

https://pubmed.ncbi.nlm.nih.gov/33664334/

https://pubmed.ncbi.nlm.nih.gov/25152028/

https://pubmed.ncbi.nlm.nih.gov/28890521/

https://link.springer.com/article/10.1007/s00240-014-0720-x

Benefits of berberine.

Written by Lee Stevenson, sorry I am a lousy editor.

This has been written for educational purposes, it should not be taken as medical advice. If you are ill please find an experienced and qualified functional medicine practitioner.

Berberine

There are many plants that contain berberine. It is best to research which may be the best fit for the individual. Barberry, bayberry, coptis, oregon grape root and many other plants. Berberine can protect against metabolic disease and diabetes. Berberine reduces joint inflammation. Berberine improves cardiovascular health. Berberine prevents depression and cognitive decline. Berberine can promote weight loss. Berberine prevents lung inflammation. It has a short half life so needs to be taken more then once a day. Berberine helps to reduce bacteria overgrowth in the gut. Berberine helps to protect the liver. Berberine has potent anti-inflammatory properties. Berberine has a broad range of antimicrobial properties and even kills parasites. The antioxidant properties of berberine are comparable to that of vitamin C. Berberine’s antioxidant and anti-inflammatory effects contribute to it ability to protect the renal system. Berberine prevents insulin resistance and improves glucose intolerance. Berberine improves kidney and liver function. Berberine increases the bodies natural steroids which reduces inflammation. Berberine prevents candida overgrowth. Endotoxins cause leaky gut. Berberine heals the gut and prevents the negative effects of the endotoxins. Berberine prevents fatty liver disease by balancing the microbiome. Berberine improves mitochondrial respiration which increases cellular ATP levels which would prevent obesity. Berberine also increase the microbes in the gut that prevent obesity. Berberine reduces B-catenin levels which would inhibit herpes and corona viruses from entering the cells.

Bererine has been found to inhibit many types of infection from amoeba to viral. It has been shown to be effective against Covid and herpes.

Excess consumption of berberine can cause stomach pain or cramping, distention, flatulence, nausea , diarrhea or constipation. Very high doses can cause low blood pressure and flu like symptoms. It can cause uterine contractions so should not be used by pregnant women.

https://www.frontiersin.org/articles/10.3389/fphar.2018.00557/full#h7

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879420/#B2

https://pubmed.ncbi.nlm.nih.gov/21592990/

https://pubmed.ncbi.nlm.nih.gov/26923892/

https://pubmed.ncbi.nlm.nih.gov/33680978/

https://pubmed.ncbi.nlm.nih.gov/33749932/

https://link.springer.com/article/10.1007/s00705-010-0779-9

Benefits of melatonin.

Written by Lee Stevenson

This is not medical advice , I am writing this for educational purposes. If you are ill please seek the aid of an experienced and knowledgeable functional medicine practitioner.

Melatonin

Melatonin has so many benefits I may not be able to describe them all. One thing to take note of with melatonin if your vitamin D levels are low it will actually disrupt your sleep and possibly cause nighmare. When vitamin D levels are adequate it promotes deep restful sleep and does not cause nightmares. If taken it should be taken about and hour before bed time. Melatonin can help restore the bodies circadian rhythm . Melatonin improves mood and prevents depression. Low melatonin increases the risk of breast cancer. Melatonin improves cardiovascular health. Melatonin is a very potent anti-inflammatory and antioxidant. It has been found to help reduce symptoms of autoimmunity and sepsis. Melatonin improves the function of the immune system. Melatonin helps to prevent over active bladder and muscle spasms. Melatonin increases the bladders capacity. Melatonin removes free radicals from the body. Melatonin prevents mitochondrial leakage which prevents the production of free radicals. Meltonin stimulates the release of antioxidant enzymes. Meltonin increases G6PD which is often times low in those with Lyme disease or who have consumed foods high in glyphosate. Melatonin inhibits the negative effects of endotoxins. Melatonin improves the health of the liver and kidney. Meltonin protects the brain and nerves from injury. Melatonin improves lung health and prevents allergies. Melatonin reduces NLRP3 expression which is overexpressed in autoimmunity, Crohn’s disease and interstitial cystitis. Melatonin alleviates the symptoms of Alzheimers disease and protects the brain from injury. The improvement of mitochondrial function by melatonin helps protect from viral infection and has been shown to protect from Covid. Melatonin also prevents viruses from entering the cells. Melatonin speeds up recovery from sepsis.

Before taking melatonin a person has to make sure they are not deficient in vitamin D which studies show most are. Vitamin D deficiency makes a person extremely susceptible to infection. A person should not take more then 5000 IU of vitamin D a day. If a person is deficient in vitamin D then they will react negatively to melatonin and it will cause disrupted sleep patterns instead of enhancing sleep.
Melatonin is an extremely potent antioxidant and it protects the mitochondria from oxidative stress. Melatonin is antiaging. This increases cellular ATP levels and enhances mitochondrial membraine potential meaning it is easier for the mitochondria to clean the bad out while transporting into the mitochondria the things needed. Melatonin is so important for mitochondria health that the mitochondria produces it’s own melatonin. If oxidative phosphorylation becomes inhibited or damaged many free radicals are formed causing the mitochondria to function even more poorly. Melatonin prevents this from happening. When oxidative phosphorylation is inhibited diabetes and obesity can occur. If melatonin is not the most potent antioxidant it is sure up there at the top in it’s power to reduce free radicals.
Melatonin has been found to protect from the harm infection like corona can cause. Melatonin reduces the outbreak of herpes and helps prevent the damage that occurs from herpes virus infections.

Taking extremely high doses can cause nausea, dizziness, headache, lethargy, sleepiness, disorientation and decreased motor skills. It should not be taken during waking hours. It can delay puberty in children because it inhibits prolactin production. It also inhibits gonadotropin-releasing hormone neurons which could also delay puberty.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412427/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409706/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300798/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652010/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8207287/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7582936/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8190272/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387000/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993480/

https://pubmed.ncbi.nlm.nih.gov/11121726/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017324/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8301107/

Benefits of NAC.

Written by Lee Stevenson, sorry I am a lousy editor.

This is not medical advice I am writing this for educational purposes . If you are ill please seek the aid of an experienced and qualified functional medicine practitioner.

NAC (N-acetylcysteine)

The FDA is trying to ban NAC so it may not be available soon. It seems it must be hurting their corporate sponsors wallet.

NAC boost glutathione levels which is one of the most potent antioxidants in the body. NAC helps to reduce the symptoms of PCOS. It improves male and female fertility. NAC prevents mitochondria and DNA damage. It reduces inflammation and oxidative stress. It improves the health of the mucus layers throughout the body including the gut and bladder. NAC promotes glutamate and dopamine homeostasis. VEGF is overexpressed during infections especially by Covid and herpes viruses. It causes damage throughout the body. NAG inhibits VEGF. NAC increases ATP levels in the cells. Most are deficient in Nitric oxide. NAC increases nitric oxide levels. NAC has been found to improve the health of the lungs. NAC reduces allergic symptoms. NAC blocks and prevents the formation of biofilms by pathogens. NAC has been found very effective at reducing the symptoms of Crohn’s disease. It helps to improve insulin sensitivity and glucose tolerance preventing diabetes and obesity. If taken in moderation it reduces excess homocysteine but if taken in excessively high amounts it can increase homocysteine levels. NAC has been found to reduce the symptoms of sleep Apnea. NAC inhibits the replication of many viruses and bacteria. NAC has been found to be effective against Covid and at reducing the replication of the herpes viruses. NAC helps prevent fatigue. NAC helps to prevent many types of eye disease and autoimmune diseases. NAC helps prevent many types of mental disorders. Xenobiotics disrupt mitochondrial function and oxidative balance. NAC restores mitochondrial function and oxidative balance.

If taken in excess it can cause nausea, vomiting, and diarrhea. It thins the blood so taking very high amounts is not recommended. Most studies I read that were effective the patient had taken NAC for at least three months. The shorter term studies seem to show very little benefits so it seems it takes a while to start feeling the health benefits of NAC.

https://pubmed.ncbi.nlm.nih.gov/21831508/

https://pubmed.ncbi.nlm.nih.gov/29043702/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306416/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8211525/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241507/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145636/

Urolithan one of the most potent microbial healing metabolites, that most no longer produce.

Written by Lee Stevenson, sorry I am a lousy editor.

Urolithins

Urolithins is produced by our gut microbes from ellagic acid which is high in most berries, pomegranate , walnuts and pecans. Urolithin is one of the most potent phytochemicals for healing and remaining healthy. It is nueroprotective, cardioprotective, hepatoprotective, it prevents diabetes, obesity, autoimmunity, and prevents systemic inflammation. Urolithin A and B and isourolithin A are the most beneficial urolithins. Unfortunately many lack the microbes to produce urotlithins or to produce the final urolithin metabolites like urolithin A because the gut microbes that do this are becoming extinct in the human gut. Antibiotic use, medications, GMO foods, processed foods, and the heavy use of farm chemicals have caused levels of those chemicals to be high in our foods. All of these are killing beneficial microbes in the human gut. Many now lack the microbes to produce urolithans. I have tried to find animal milks that would contain them but have not found any yet. You can buy urolithin A as a supplement. Urolithin increases ATP, NAD+, levels and also increases Sirt1 and PGC1 which would increase mitochondrial respiration. Also PGC1 helps to inhibit herpes viruses. This would also help reverse some of the effects of aging. Most centurions produce high levels of urolithin. Urolithin increases mitochondrial biogenesis. These are my own thoughts but I wonder if those who get any of the herpes viruses may be lacking the microbes that produce urolithin because many of the ways herpes viruses and Covid use to infect the cells would be prevented with urolithin. Urolithin inhibits most cytokines involved in sepsis and systemic inflammation. It prevents autoimmunity. It prevents the negative effects of endotoxins. I suspect this may also be why so many are so sensitive to mold toxins now. Many now lack the microbes to produce urolithin. At the rate things are going pretty soon certain people poop will be worth more then gold if their families have the microbes that are becoming extinct in the human guts. They most likely will start farming poop for microbes trying to find the missing microbes and restore them. It is sad that most no longer produce one of the most beneficial microbial metabolites.

Some more benefits of urolithin is it prevents brain aging. Urolithins are amazing molecules. They act as prooxidants in the right places and antioxidants in the right places. They are miracle molecules. Urolithin improves all around brain function and hormone levels. You can be almost certain those who are obese are lacking the microbes that produce urolithin. Urolithin increases life span and is neuroprotective.

Bifidobacteria pseudoctenulatium and Akkermansia munciphilia first break down ellagic acid then it is farther converted to a variety of urolithins by Gordonibacter urolithinfaciens and Gordonibacter pamelaeae. Most lack the species to fully convert urolithins now days. The days of centurions is coming to and end sadly. As the pharmaceutical, biotech industry and chemical industries toxins slowly drive our gut microbes to extinction the human health is going to only worsen.

https://www.nature.com/articles/s41430-021-00950-1#Sec12

https://pubmed.ncbi.nlm.nih.gov/33214614/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347929/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918969/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918969/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985387/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407063/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070385/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566096/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007722/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141696/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851346/

https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(21)00118-0

https://actu.epfl.ch/news/pomegranate-finally-reveals-its-powerful-anti-agin/

https://www.sciencedirect.com/science/article/abs/pii/S1756464618301324