Written by Lee Stevenson, sorry I am a lousy editor.
I have written this for educational purposes this is not medical advice. If you are ill please seek the aid of a qualified and experienced functional medicine practitioner.
This is one substance I would only use under the guidance of someone very knowledgeable and experienced at it’s use. Methylene blue is so potent that just a tiny spec of a drop is all that is needed. Any more then that can have some negative effects on the body. Methylene blue is used as an antidote for cyanide poisoning. Methylene blue is also used in metformin poisoning.
Methylene blue can help reverse Alzheimers if used in the correct amount but would most likely cause it if taken in excess. Methlyne blue reduces oxidative stress and can break down the fibrous tissue found in the brains of those with Alzheimers. If taken in excess methylene blue can actually cause excess oxidative stress. In low dose methylene blue enhances memory retention and memory retrieval.
If used correctly methylene blue inhibits many of the inflammatory proteins that cause sepsis, inflammatory disease and autoimmune disease. This is part of the reason methylene blue reduces pain. Methylene silences neurons that are over firing, this is something that occurs in interstitial cystitis.
I do not think a person should take methylene blue daily because it is an MAO inhibitor so can cause serotonin levels to get too high and eventually lead to serotonin syndrome. This also means it could also inhibit the degradation of histamines. Also high dose of methylene blue can inhibit nerve firing.
Low dose methylene blue can improve mitochondrial function. It improves cellular respiration which helps prevent obesity and diabetes.
Methylene blue can help prevent viral infection with RNA viruses such as Covid.
Vassopressin levels get low during sepsis and inflammatory diseases. Methylene blue helps to preserve vassopressin which would speed up recovery time.
Taking high dose amounts of methylene blue alters microbiome to a type that is inflammatory and destructive to the brain but low dose has not effects on the microbiome. Methylene blue in low dose also reduces gut inflammation but because in high dose it alters the microbes to inflammatory ones it will actually increase inflammation in high dose.
Methylene blue helps protect the body from ischemia (oxygen deprivation) induced damage.
When the citric acid cycle (electron transport chain) is not working methylene blue can help bypass it. So those with a sluggish citric acid cycle may be able to reap the benefits of lysine if they supplement with methylene blue. If the citric acid cycle is sluggish a person my react when taking lysine. But lysine has many many health benefits so supplementing when ill is very beneficial.
If taken in low dose methylene blue is cardioprotective. If taken in high does it can cause heart arythmias, coronary vasoconstriction which will increase blood pressure. It can turn urine blue or greenish blue. It can cause hemolytic anemia, hyperbilirubinemia, pulmonary edema, and serotonin toxicity. These are all very serious and life threatening things. This show the importance of having someone very experienced in it’s proper use , so a person should not take this on their own without proper guidance.