Good and bad of methylene blue.

Written by Lee Stevenson, sorry I am a lousy editor.

I have written this for educational purposes this is not medical advice. If you are ill please seek the aid of a qualified and experienced functional medicine practitioner.

Methylene blue

This is one substance I would only use under the guidance of someone very knowledgeable and experienced at it’s use. Methylene blue is so potent that just a tiny spec of a drop is all that is needed. Any more then that can have some negative effects on the body. Methylene blue is used as an antidote for cyanide poisoning. Methylene blue is also used in metformin poisoning.

Methylene blue can help reverse Alzheimers if used in the correct amount but would most likely cause it if taken in excess. Methlyne blue reduces oxidative stress and can break down the fibrous tissue found in the brains of those with Alzheimers. If taken in excess methylene blue can actually cause excess oxidative stress. In low dose methylene blue enhances memory retention and memory retrieval.

If used correctly methylene blue inhibits many of the inflammatory proteins that cause sepsis, inflammatory disease and autoimmune disease. This is part of the reason methylene blue reduces pain. Methylene silences neurons that are over firing, this is something that occurs in interstitial cystitis.

I do not think a person should take methylene blue daily because it is an MAO inhibitor so can cause serotonin levels to get too high and eventually lead to serotonin syndrome. This also means it could also inhibit the degradation of histamines. Also high dose of methylene blue can inhibit nerve firing.

Low dose methylene blue can improve mitochondrial function. It improves cellular respiration which helps prevent obesity and diabetes.

Methylene blue can help prevent viral infection with RNA viruses such as Covid.

Vassopressin levels get low during sepsis and inflammatory diseases. Methylene blue helps to preserve vassopressin which would speed up recovery time.

Taking high dose amounts of methylene blue alters microbiome to a type that is inflammatory and destructive to the brain but low dose has not effects on the microbiome. Methylene blue in low dose also reduces gut inflammation but because in high dose it alters the microbes to inflammatory ones it will actually increase inflammation in high dose.

Methylene blue helps protect the body from ischemia (oxygen deprivation) induced damage.

When the citric acid cycle (electron transport chain) is not working methylene blue can help bypass it. So those with a sluggish citric acid cycle may be able to reap the benefits of lysine if they supplement with methylene blue. If the citric acid cycle is sluggish a person my react when taking lysine. But lysine has many many health benefits so supplementing when ill is very beneficial.

If taken in low dose methylene blue is cardioprotective. If taken in high does it can cause heart arythmias, coronary vasoconstriction which will increase blood pressure. It can turn urine blue or greenish blue. It can cause hemolytic anemia, hyperbilirubinemia, pulmonary edema, and serotonin toxicity. These are all very serious and life threatening things. This show the importance of having someone very experienced in it’s proper use , so a person should not take this on their own without proper guidance.

Benefits of Lysine.

Written by Lee Stevenson, sorry I am a lousy editor.

This is not medical advice I am writing this for educational purposes. If you are ill please seek the aid of a functional medicine practitioner.


When you see a letter in front of a supplement it means whether it is bioavailable to the body or not, in other worlds if it has a D infront of it the body has to convert it to use it. If it has an L in front of the letter it means the body can readily use it.

Lysine helps to regulate the pineal gland, mammary glans and ovaries. Lysine is needed for hormone production in the body.

The body cannot properly metabolize fats if we are deficient in lysine. If a person reacts when taking lysine they may have issues with their citric acid cycle. If this is the case they may need to supplement with carnitine because our bodies produce carnitine from lysine.

L-lysine inhibits herpes virus replication. Also supplementing with zinc makes it even more effective.

Lysine improve liver function which can prevent body weight gain.

It helps to protect the adrenals by preventing excess adrenal hormone levels in times of stress. When L-arginine and Lysine were taken together it increase the effectiveness. L-lysine also enhances tolerance to pain. Lysine has also been found to improve mood and behavior.

Lysine improves the bodies ability to absorb and use calcium. It prevents calcium from building up in the body while improving the bodies ability to use calcium. Lysine and arginine speed up the healing of bone.

Lysine speeds up wound healing and improves the healing of soft tissues in the body. Lysine is needed for proper protein formation and function in the body.

Lysine helps to prevent high blood pressure.

Some symptoms of Lysine deficiency are apathy, blood shot eyes, depression , fluid build up or retention in the body, fever blisters, hair loss, loss of energy, fatigue, muscle loss, stomach ulcers, reduced immunity and dizziness. Lysine deficiency can damage the liver.

Taking excess lysine can cause gall stones, abdominal pain and diarrhea. If you react when taking Lysine it can indicate your citric acid cycle is sluggish. It would be a good idea to correct that before taking lysine.

Lysine and arginine compete with each other so taking high doses of one or the other can cause an imbalance in one or the others levels. Lysine helps with herpes because herpes is dependent on arginine. By increasing lysine it makes it more difficult for herpes to use arginine.

Benefits of horny goat weed.

Written by Lee Stevenson , sorry I am a lousy editor.

This is not medical advice , I am writing this for educational purposes. If you are ill please seek the aid of a qualified and experienced functional medicine practitioner.

Horny Goat Weed (Epimedium)

It boost testosterone at very high doses. In low doses it improves bone health. It can increase estrogen in women. It is high in berberine so will have the same anti-inflammatory , antioxidant and antimicrobial effects as others plants that contain berberine. It increases male sexual stamina and increases male fertility. It seems to normalize a womens hormones if they are estrogen dominant. It improves blood flow by increasing nitric oxide. It may help to stimulate repair of damaged heart tissue.

Horny goat weed can actually help nerves to grow back after being damaged. It may protect the brain from damage and help to prevent alzheimer. Because horny goat weed stimulates the growth of neurological tissue it can also stimulate healing in the brain.

It can reinvigorate hair follicles and help with baldness by increasing insulin like growth factor 1 which is usually low in autoimmune disease and inflammatory diseases.

Honey goat weed helps to heal the adrenals and help restore immune system balance. This results in reduced pain.

In high doses horny goat weed can irritate the stomach.

Horny goat weed correct issues in many metabolic pathways including those involved in burning fat.

Benefits of velvet bean.

Written by Lee Stevenson, sorry I am a lousy editor.

This is not medical advice I have written this for educational purposes. If you are ill please seek the aid of a qualified and experienced functional medicine practitioner.

Velvet bean (Mucana pruriens)

Velvet bean has been found to be neuroprotective. It has been shown to prevent or reverse the effects of Parkinson’s disease. It is a good source of protein for those who have sulfation issues because the proteins in velvet bean are low sulfur proteins. It does contain anti-nutrient substances so should not be taken near meals. It contains a trypsin inhibitor which could help those with COPD but it inhibits the breakdown of proteins in the body. The levels of antinutrients in Velvet bean are very low so it would take very excessive amounts to cause negative health effects. It can cause damage to the pancreas. This is why I believe Velvet bean should be pulsed. Velvet bean contains L-dopa which can help increases dopamine levels the feel good hormone. This can help to reduce the effects of stress helping to protect the adrenals. When the adrenals are upregulated and get depleted or damaged the body will shunt progesterone to produce adrenal hormones the can have dramatic effects on the hormones in the body and can make menstruation very painful for women. By protecting the adrenals you can reduce the risk of this happening. Most beans contain trypsin inhibitors . It is when we consume high amounts that it can be a problem. Velvet bean is high in tryptamine. If tryptamine levels get too high it can cause a reaction similar to that of histamines. Velvet bean has an insulin mimetic so can decrease glucose levels in the blood which would help with certain types of diabetes. Velvet bean enhances memory and improves kidney function.

Velvet bean can help to improve sleep quality and increase tolerance to stress.

Velvet bean has been shown to reduce some of the effects of aging, arthritis and inflammatory disease. It has been shown to help prevent high blood pressure. Velvet bean also has potent antioxidant properties. Velvet bean increases antioxidant enzymes.

It can decrease body temperature but increases tolerance to pain. It also neutralizes Cobra venom. It increases sexual stamina and fertility. Because velvet bean improves the health of the HPA axis it would help to restore normal hormone levels. It also could help restore hormone levels because it restores the membrane potential in mitochondria which means nutrients could be taken into the mitochondria and waste could be removed more easily which would also improve the mitochondrias ability to burn fat.

Velvet bean stimulates the release of growth hormone which is usually inhibited during chronic illness. It would prevent muscle atrophy and increase muscle growth.

Most recommend starting with 5 grams a day. Side effects if taken in excess are headache, pounding heartbeat, psychosis-being easily agitated, confusion, delusions or hallucinations. Velvet bean consumed in excess can cause stomach ulcers. Do not take velvet bean during the day or when driving it reduce motor function in the body. If used in moderation velvet bean is actually gasoprotective.

Benefits of evening primrose oil.

Written by Lee Stevenson, sorry I am a lousy editor.

This is not medical advice I am writing this for educational purposes. If you are ill please seek the aid of a qualified and experienced functional medicine practitioner.

Evening primrose oil. (Oenothera biennis)

It has been found to be very effective for reducing breast pain, premenstrual and menstrual pain in women. It is very high in flavonoids know to be potent at reducing inflammation and oxidative stress. It helps to prevent atopic dermatitis which usually results from autoimmunity. It suppresses the cytokines that cause sepsis and autoimmunity. Evening primrose oil improves the health of the skin by improving water balance. It prevent eye problems caused by autoimmunity and inflammation. It has been shown to reduce pain. It increases cognitive function and vitality. It is safe for breast feeding mothers. Evening primrose oil does reduce lithium levels in those taking lithium. The whole plant can be used. The leaves and roots are good for healing the gut.

Benefits of Rhodiola.

Written by Lee Stevenson, sorry I am a lousy editor.

I am writing this for educational purposes it should not be taken as medical advice. If you are ill please seek the aid of a functional medicine practitioner.

Rhodiola (Rhodiola Rosea)

It is an adaptogen so it helps normalize adrenal hormones. It prevents the negative effects of stress on the body. It increases serotonin by inhibiting MAO so if a person consumes tryptophan while taking it they could develop serotonin syndrome. It has been shown to promote longevity. It decreases fatigue and helps prevent muscle damage. It increases endurance. It increases antioxidant enzymes in the body. It has been found to reduce pain induced by stress. It has been found to improve the quality of sleep. Those who are TH1 dominant should not take it because it increases TH1 levels. Rhodiola activates the genes that are inhibited by herpes viruses and Sars-Covid. Rhodiola also reduces the inflammatory cytokines induced by herpes viruses and Sars-Covid. Rhodiola has been found to inhibited RNA virus entry into cells. Rhodiola has potent antibacterial properties.