This is not medical advice I am posting this for educational and informational purposes.
I have a lot more to add to this but need a break and then I will finish it. I am going to add the things that negatively impact health and how it happens. Some of it I have covered but I have not covered the how part of it I only covered things that may help correct it.
Because probiotics can cause sepsis if you have ulcers or your gut is too porous I consumed a lot of mucilage and took bismuth in order to make sure my gut healed enough that would not happen.
To fully grasp the information here and to grasp the information in the links you will need to understand that Germ Theory and Terrain Theory have been proven wrong and that is why our Facebook group Synergistic Health decided we need a new theory “Enviroment and Biome Theory of Health”
Germ Theory and Terrain Theory are wrong.
This article discusses how our microbiome effect the whole body even the blood brain barrier.
In this post I am going to try and show how our environment, biome of our environment and our won biome effect our health. This shows that our Facebook group Synergistic Health is correct with our theory “Environment and Biome Theory of Health” is correct and that germ theory and terrain theory are incorrect. Learning this will help people understand why their genes have very little impact on their health compared to the above mentioned things. I also list the things that may be able to correct them.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102499/
In all the research I have read gut diversity increases health and longevity and is found to be a commonality in centurions.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051225/
There is a myth we should alkaize our digestive system must be acidic and alkalinity cause pathogenic and hydrogen sulfide producing bacteria to increase. This causes sulfation issues and increased ammonia getting the body stuck in a cycle. Bile and digestive enzymes become inhibited which cause high estrogen levels and copper will become biounavailable. You must break this cycle by getting ammonia levels down. BH4 levels get low when this happens eating protein increases ammonia levels. Short chain fatty acids balance our T cells so it is important to increase SCFA producing bacteria. I did a blog post on reducing ammonia levels (alkalosis). I did a post on reducing akalosis. I also did a summary of my notes which covers many of these things. If you search for akalosis and summary you should be able to find the information.
Fiber especially inulin increases the good gut bacteria. Exercise also increases our good gut bacteria. Reducing stress or learning to deal with stress increases our good gut bacteria. Ghee is high in butyrate which increases our good gut bacteria.
Egg and milk allergies indicate high Staphylococcus Aureus levels. This is caused by low microbiota that breaks up biofilms and produces natural antibiotics. This can also be caused by low lactobacillus paracasei, lactobacillus adolenscentis and lactobacillus rhamnosis levels.
I do not mention the strains that produce histamines because they are usually not a problem unless something is wrong in the body and they are needed for gut and body health. Avoiding the foods that cause them to produce histamines is more effective. Fermented foods, and aged meats and many cheeses will cause them to produce histamines. Some cheeses like Gouda and Parmesion have species of microbes that reduce histamines. This is why overconsumption of them can cause constipation because histamine stimulates stomache acid production. Those with low stomach acid production may benefit from eating foods that increase histamines.
An imbalance in our gut bacteria can lead to the production of high substance P levels which leads to systematic inflammation. If levels get high enough a person will start to lose their hair, they will get burning in their skin especially at night. The burning mostly occurs in the scalp and down the spine. I posted on how to reduce substance P.
When replacing a microbe you may be lacking it is normal to experience cramps and bloating until they get established. Taking the same probiotic daily can cause gut dysbiosis which is as bad as when candida goes pathogenic and can cause candida and H Pylori to switch from commensal to pathogenic. Probiotics should be alternated and one should take a break from them to let the microbial community balance out.
Most Bifidobacterium and Lactobacillus have some oxalate degrading abilities. The microbiota that produce vitamin B12 need chromium to be present to produce it.
Exercise increases our good gut bacteria. Stress and trauma increase our bad bacteria so it is very important to learn to meditate , pray and not to dwell on things you can do nothing about and do your best to get over trauma and do not hold grudges or be resentful or hateful. When we have a lot of negative emotions it increases the gut bacteria that increases adrenaline and it can tax our adrenals.
Diets rich on complex carbohydrates have been shown to prevent infection from food born pathogens. Processed sugar has been found to dramatically increase risk of infection from ford born pathogens.
Often times a persons microbiome is influenced by their sexual partners. Their sexual partner may have different metabolic factors so could appear to be unaffected. Usually a person sexual partner should be treated for dysbiosis or infection also to prevent constant reinfection or constant microbiome disruption.
Galacto-oligosaccharides increase absorption of nutrients, and increase the beneficial bacteria that are important in health mental health and cognition. It prevents constipation and helps protect from food born pathogens. It increases the microbiome that reduces anxiety and pain. It is derived from raw milk and is destroyed during pasteurizing. It also decreases the risk of pulmonary infections. It reduces almost all inflammatory markers in the body. It reduces intestinal inflammation. Galacto-oligosaccharid and fructo-oligosaccharid helps to prevent diabetes.
Our bodies secrete FUT2 to modulate our immune system and to keep our good microbiome health. Many things can make us deficient in FUT2 enzymes which causes a loss of our good gut microbiome and can lead to inflammatory bowel diseases and gut dysbiosis. Fructooligosaccharide and oligosaccharides can replace FUT2 until it is corrected. This is can also result from a deficiency in the microbiota that stimulate IL-22
A loss of our gut microbiome can cause raised zonulin levels which results in many food intolerances, metabolic issues , increase susceptibility to infection and if not corrected can lead to acidosis or alkalosis. Zonulin regulates gut permeability if levels get too low we can develop malabsorption issues. If zonulin levels get to high we can develop many health problems. It can also lead to interstitial cystitis and damage the blood brain barrier which results in the loss of protection of the brain and can lead to infection , encephalopathy and even chira which is a life threatening condition. Increased zonulin levels causes depression, anxiety and can even cause paranoid delusions and psychosis. Mold toxins can increase zonulin levels. BT Toxin found in GMO increase zonulin levels. Farm chemicals which are found to be heavy in our food increases zonulin levels especially glyphosate and glufosinate. It is very important to eat organic when possible. A diet high in fiber and resistant starches increases the microbes that reduce zonulin. Oddly our sterile lifestyles have caused a loss of the microbes that keep zonulin levels balanced. They have found those who are in nature and work with the soil a lot get the good microbes that keep zonulin levels balanced. Unfortunately glyphosate and glufosinate are killing those microbes in the soil which is making it more and more difficult for a person to get those microbes. Endotoxins and mycotoxins increase zonulin levels making us more prone to leaky gut. Leaky gut causes systematic inflammation which can lead to autoimmunity. Butyrate producing gut bacteria reduce zonulin levels helping to prevent leaky gut. Butter and raw milk is high in butyrate. Inflammation causes increased zonulin levels so microbes that reduce inflammation will decrease zonulin. When zonulin levels are how toxins the body would not absorb but would get excreted are easily absorbed which causes high heavy metal and other toxins levels in the body. High zonulin levels also result in food particles entering the blood stream which causes a lot of food sensitivities. This can be corrected by addressing the leaky gut. When zonulin levels are high it increases mast cell degranulation which can lead to mast cell activation syndrome or mastocytosis. This increases histamines leading to autoimmunity and allergies. This also will correct itself once zonulin levels are reduce. Those with high zonulin levels should avoid gluten and gliaden until it is corrected because they raise zonulin levels. High zonulin and high inflammation levels has been linked to just about all types of chronic illness. Inflammation can cause high zonulin levels, high zonulin levels can lead to inflammation creating a cycle that is difficult to break. Inflammation disables the immune system and is why so many illnesses like tick born illness, candida and many other infections are becoming epidemic. Almost all illness can be link to zonulin.
https://www.sciencedirect.com/science/article/pii/S2352551717300288
https://www.physiology.org/doi/full/10.1152/physrev.00003.2008
https://www.frontiersin.org/articles/10.3389/fmicb.2017.01936/full
https://www.tandfonline.com/doi/pdf/10.1080/21688370.2016.1251384
Our gut microbiome regulate our zonulin levels which regulates the tight junction layer. When zonulin is high then we develop leaky gut which causes chronic illness and even effects our brains. Our gut bacteria even regulate our HPA axis. Microbes that increase IL-10, T regulatory cells and reduce inflammation will reduce zonulin levels which will restore the tight junction protein layer. Also stress increases zonulin so microbes that reduce stress will also decrease zonulin levels.
https://www.tandfonline.com/doi/pdf/10.1080/21688370.2016.1251384
https://link.springer.com/article/10.1007/s00394-018-1784-0
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288588/
Our sterile lives have added to the increase in zonulin levels. Also nutrient deficiencies cause by over farming land and chemicals like glyphosate and glufosinate that chelate nutrients are causing nutrient deficiencies which increases zonulin. This indicates the the biome of our environment is also important for our health. It also indicates that our environment itself can influence our health.
http://www.pnas.org/content/106/39/16799.long
Nutrient deficiencies also stimulate zonulin and so do bad fats and excessive meat consumption. Excess vitamin B12 increases zonulin levels. I do not supplement with it, I nurture my gut microbiota that produce it and I make sure I get cobalt which they need to produce B12. On the other end of the scale zonulin deficiency can result in the inability to absorb nutrients. This shows the importance of learning to achieve homeostasis. I cannot find studies showing that inhibited zonulin causes malabsorption but I have noticed those who have high levels of the bacteria that inhibit zonulin and low levels of the ones that stimulate zonulin have malabsorption issues.
https://www.sciencedirect.com/science/article/pii/S0041134514008045
High zonulin levels can lead to decreased intestinal motility which causes the food to sit in the digestive tract and ferment instead of digesting. This increases the ammonia, hydrogen, sulfide and methane producing microbes which raises zonulin levels even higher. If I ever get a chance to write a book I will cover it in more detail. Once this cycle starts it is very hard to break and a person will not be able to absorb nutrients because their food is not getting broken down properly.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111132#s4
So all this being said the bigger the variety of gut microbes we have the more balanced our zonulin becomes.
Butyrate producing microbiota increase TGF-B which is needed to prevent some commensals from becoming harmful. A deficiency in TGF-B can lead to inflammatory bowel disease which can cause bile to be inhibited. The most important of these are F Prausnitzii, Clostridium Leptum, Eubacterium Rectale and Roseburia. If deficient in IL-10 or TGF-B the microbiota that stimulates bile will become pathogenic in nature IL-10 and TGF-B work together to keep them in check so they continue to function properly. I discuss bile in more detail at the end of this article.
https://link.springer.com/article/10.1007/s00535-017-1350-1
https://www.tandfonline.com/doi/full/10.3109/0284186X.2015.1054949
Raw potatoes, inulin, chickpeas and other legumes feed the gut bacteria that prevent gliaden and gluten intolerance. Too much of these can increase the glucose levels in the blood. That may be good for those with malabsorption but high glucose levels can lead to cancer and other health problems.
Increased CB1 receptor activation causes leaky gut which can lead to food intolerances from our gut becoming too porous. This can lead to increased LPS levels which can lead to endotoxemia and sepsis. Increased zonulin also does this. Stress increases zonulin.
The PH of the gut and bladder should be between 4 to 5. The lower the number the more acidic the high the number the more alkaline. We do not want alkaline it causes infection and gut dysbiosis. Candida and H Pylori will go from commensal to pathogenic.
Bloating can be from taking too much of a certain probiotic which can lead to dysbiosis , inflammation, ulcerations, or high histamines. High histamines will cause acid reflux. Low histamine inhibits bile and will cause bile reflux constipation and low stomach acid production. If you have low histamines fermented foods will increase the histamine producing bacteria but be cautious do not increase them too far. We can also become bloated if candid or H Pylori go from commensal to pathogenic.
Increased gut permeability (leaky gut) can lead to bone loss, autoimmunity, and many metabolic issues.
Our gut bacteria need carbohydrates but many avoid them. There are good carbs and bad carbs.
A microbiotia accessable carbohydrate diet increases beneficial bacteria that produce short chain fatty acid. This consist of fiber and carbohydrates. This increases the bacteria that produce short chain fatty acids. If we do not produce enough SCFA we will become constipated and bile production will become inhibited. This will also happen if we develop malabsorption from having high bacteroidetes, methane producing and sulfur digesting bacteria. They contribute to malabsorption, constipation and inhibited bile production from a lack of SCFA in the body. Our blood glucose levels will also become very low and we may develop high insulin levels. Clostridium infection is also a major cause of this and indicates we are lacking the microbiota that protect us from it. This can cause a cycle that is hard to break because bile is needed to prevent clostridium infection.
High histamines usually indicates low bifidobacterium levels. Bifidobacterium degrade histamines. Low Bifidobacterium can cause weight gain in some people and can lead to anxiety, difficulty sleeping and difficulty concentrating. Our histamine degrading bacteria need vitamins A,C, E and Zinc. Bifidobacterium which there are many species produce folate. Most Bifidobacterium increases IgA which prevents food intolerances and allergies. Bifidobacterium also break down gliaden. Excess gliaden can raise zonulin levels leading to the tight junction layer becoming more permeable resulting in leaky gut.
Lactobacillus needs vitamin A and consuming it has been shown to restore lactobacillus. Most lactobacillus prevent candida and fungus infections. Most Lactobacillus prevent lung infection. Most Lactobacillus increase IL-10. IL-10 is needed for commensalism. Those deficient in Lactobacillus will be extremely underweight.
Click to access c191fc3c8efbd745d5583d6be940a4dcae06.pdf
Most probiotics should be taken with an oligosaccharide. They help feed them and get them established. Pectin also protects the good bacteria helping it to thrive. Olive oil has been found to prevent them from making TMAO. If TMAO levels get too high we can develop a fish like smell, diabetes and/or cardiovascular disease.
Lactobacillus Reuteri increases oxytocin which helps keep us calm and helps prevent depression. It also helps prevent diarrhea. It increases intestinal absorption of nutrients. It prevents cavities and promotes dental health. It protects against pathogens and parasites. It has been shown to help with autism. L Reuteri produces food need by most of the other commensal bacteria. It requires sugar to produce the food the commensal microbes need. L reuteri also help prevent asthma. Helps restore normal vaginal and bladder microbiome. If you are sensitive to sugars and starches it could be an indication you are deficient in L Reuteri. L Reuteri breaks down sugars and starches. A deficiency in Lactobacillus Reuteri can also contribute to milk allergy and a lower resistance to pain. It prevents gingivitis and periodontal disease. It helps keep H Pylori commensal. L Reuteri improves the production of bile.
Clostrium Leptum has been found to be low in those with inflammatory bowel disease and Chohn’s disease. It breaks down carbohydrates and produces butyrate. It reduces inflammation.
I believe L Reuteri and L Fermentum are the same species. Often times research papers state that they are the same species.
Lactobacillus Fermentum found in raw goats milk protects from urinary tract infection and food born pathogens. It has been shown to increase other lactobacillus bacteria. This would help those who have difficulty gaining weight. It is resistant to most antibiotics and has been found to transfer that ability to the other but microbes. This also would help with lactos intolerance. L Fermentum prevents skin rashes and eczema By increasing TH1. It prevents IgA related allergic disease. L fermentum helps prevent urinary infection. Low I IgA levels are common in inflammatory bowel disease and those who have malabsorption disorders. Reduces endotoxins. Helps protect from cavities and gingivitis.
Bacteroides Vulgatus increases bile production, if levels are low a person is susceptible to inflammatory bowel disease. If levels get too high a person will develop celiac disease. This occurs if a person is lacking the microbiotia that stimulate IL-10, SMAD3 and TGFB.
Pediococcus pentosaceus prevents clostridium infection of the digestive system by reducing zonulin. This would improve bile production. It also reduces inflammation. It produces natural antibiotics that fight bacteria.
Bacillus Coagulins prevents lactose intolerance. Helps break down food better increasing nutrient absorption. Helps prevent diarrhea. Prevents gas, bloating and intestinal inflammation. Helps prevent constipation. Reduces endotoxins. Improves bladder and vaginal health. Helps keep H Pylori commensal.
Bacillus Subtilis produces food needed by the other commensal microbes has been shown to balance the gut microbiome. It prevents gastrointestinal and urinary tract infection. It is found in soil. It stimulates IgM, and IgG which important part of immune function. Protects the DNA and has antioxidant properties. Helps prevent diabetes and cardiovascular disease. If it is supplied with lactulose which is found in raw milk but destroyed during pasteurization it will prevent constipation. It reduces inflammation and has been shown to reverse irritable bowel disease. It Balances our T cells which would prevent allergies and autoimmunity. It prevents H Pylori and Candida from becoming pathogenic. Reduces endotoxins and heals the liver and kidneys. It prevents skin rashes and lesions. It increases our ability to tolerate heat. Helps break down phytic acid preventing it from being and antinutrient. B Subtilis has been shown to reduce blood pressure and prevent atherosclerosis. B Subtilis communicates with the body to let is know what is going on. It kind of acts like a soldier and a nurse. It stimulates IFN-y in spleens of mammals which is an important part of the bodies ability to fight infections. Seems more important for fighting infection then dendric cells and natural killer cells. IFN-y prevent viruses from being able to adhere to cells. Increasing IFN-y increases CD8 molecules. Those who are TH1 dominant should avoid this strain it increases TH1.
https://iai.asm.org/content/75/3/1167
Lactobacillus sanfranciscensis helps degrade phytate preventing them from being and antinutrient. Decreases gut permeability and prevents obesity. Reduces symptoms of inflammatory bowel disease. It is found in raw sour bread dough.
Lactobacillus pentosus found in fermented olive products. It helps prevent food born pathogens. It helps break down carbohydrates. Helps reduce symptoms of lactose intolerance. It can break down a wide variety of sugars and carbohydrates.
Lactobacillus Salivarius reduces histamines. Protects the throat, mouth and nasal cavities from infection. It helps prevent cavities. They help keep the ph of the intestines balanced. It helps with nutrient absorption especially folate. It reduces nausea, bloating, cramping and inflammation in the digestive system. It protects us from food born pathogens. It protects us from getting strept throat and halitosis. It lowers cortisol levels and reduces stress and anxiety. L Slivarius increases endurance. Helps prevent lactose intolerance. It prevents flatulence. Has been shown to protect the pancreas. Has been shown to reverse dermatitis.
Oxabacter Formigenes reduces oxalates and reduces pain. It is the primary oxalate degrading bacteria in the gut.
Lactobacillus Paracasei inhibits infection and helps reduce ammonia producing bacteria. It is a subspecies of Lactobacillus Casei which has many of the same benefits. It also prevents anxiety but not depression. L paracasei especiall ssp Casei prevents obesity. L Casei reduces the duration of infections. L Paracasei helps prevent allergies. L paracasei and ssp L Casei should not be taken by those with high histamines. It prevents halitosis and cavities. It has been shown to protect the nasal cavities, mouth and throat from infection.
L Casei protects us from pathogens that cause diarrhea and antibiotic induced diarrhea. It improves colon health and inceases the commensal bacteria that help prevent depression and anxiety. Helps protect the gums from infection. Has been shown to protect the health of the pancreas. Increases IL-10 and TGF-B.
Lactobacillus Casei ssp shirota prevents constipation. Increases serotonin. It improves mood and prevents depression. It has the best long term effects at improving mood.
Lactobacillus Brevis prevents urinary and intestinal infection by regulating the PH of the digestive system and renal system. It helps keep it from getting too akaline. Lactobacillus Brevis improves cellular immunity it protects the gut from excess bile acids and keeps H Pylori commensal. It produces natural antibiotics that protect the gut from pathogens.
Streptococcus Thermophilus is needed by most of the gut bacteria to get established especially lactobacillus debrueckii. S Thermophilus helps with lactose intolerance. It prevents cavities and infection in the nose, throat and mouth. Helps prevent inflammatory bowel diseases. It accelerates healing in the gut.
Lactobacillus Debrueckii is needed to establish the commensal microbiome and to prevent C Diff infection. It also prevents inflammation. It is found in butter milk. It also helps keep H Pylori commensal. It helps degrade milk proteins. It also helps prevent liver disease. L Debrueckii also prevents fungus infection. It also prevents obesity.
lactobacillus Plantarum is needed to balance our gut bacteria which helps prevent dysbiosis. It also helps prevent diabetes. Helps prevent candida and fungus infections. Helps prevent inflammatory bowel diseases. It reduces HIV, enhances memory and reduces brain inflammation. Reduces abdominal pain.
Saccharomyces Boulardii helps prevent autoimmunity, protects from diarrhea caused by pathogens. Helps keep H Pylori commensal. Helps prevent inflammatory bowel. Saccharomyces Boulardii helps with gluten intolerance and reduces symptoms of SIBO.
Bifidobacterium bifidum helps in the production of many B vitamins. Prevents celiac diseas, milk allergies and many other food sensitivities. Reduces histamines. Improves immune function. Prevents ulcers and diarrhea. It is important for vaginal homeostasis. Has been shown to reduce symptoms of inflammatory bowel diseases. Prevents constipation and lung infection. Prevents pouchitis and infections in the lining of the intestines. Has been found to improve immune function. Prevents eczema. It also produces the B vitamins common to Bifidobacterium but also produces vitamin K2. It helps those who do not produce enough lactase because it breaks down lactose. Increases red blood cell production helping to prevent anemia. Has been shown to reduce the severity of the flu and common colds.
Bacillus Coagulans found in the soil , it improves bowel movements, helps with inflammatory bowel diseases, reduces bloating and pain in the digestive system. It also decrease the inflammatory C-reactive protein which is high during infection. It reduces intestinal gas. Reduces the risk of infection especially by influenza. Has been shown to reduce arthritis symptoms. It has been shown to help with gluten intolerance and allergies. It has been shown to reduce symptoms of SIBO. It has been shown to prevent food born pathogens. Is effective at fighting a broad range of pathogens. It reduces symptoms of arthritis if it has an adequate supply of inulin.
Saccharomyces Cerevisiae reduces oxidative stress and free radicals including hydroxy radicals and prevents excess nitric oxide production. Helps prevent iron toxicity. It stimulates the good inflammatory cytokines while inhibiting the bad ones. It helps in developing humoral immunity. Can reduce candida infection but if taken in excess will cause symptoms that are exactly the same as candida infection and is often times more common in those who are believed to have candida infections in the bladder. It helps those who have phenylketonuria or proteinuria it breaks down proteins like phenylalanine. Saccharomyces Cerevisiae prevents acne.
Lactobacillus gallinarum prevents urinary tract infection and reduces oxalates. It reduces symptoms of allergy. It helps break down phytic acid preventing it from being an antinutrient.
Bacillus Subtilis found in soil protects and heals intestinal epithial cells. It is improtant in the proper absorption of nutrients. If deficient in B Subtilis you will suffer from Malabsorption syndrome. It helps keep our T cells balanced. It is needed for digestion of carbohydrates. Has been shown to keep H Pylori commensal and fight food born illness. Has a broad range of antimicrobial properties.
Lactobacillus Helveticus is found in cheeses like parmesian, cheddar, swiss cheeses, buttermilk and cheddar cheese. Protects the gut health and is a butyrate producing bacteria. It reduces neurological inflammation and restores cognitive function. It helps prevent anxiety and depression. It improves sleep and prevents lung infection. It reduces parathyroid hormone and improves calcium metabolism. It improves learning and cognition. It fights candida and prevents dermatitis. It fights cancer and reduces inflammation. L Helviticus also prevents lung infections. It is and ACE inhibitor so prevents high blood pressure. It is important for whole body health and protects the liver and kidneys. It helps prevent lactose intolerance. It reduces anxiety and promotes the feeling of well being. It prevents mood swings and aggressive behavior. It helps prevent depression.
Bifidobacterium Longhum helps prevent anxiety and depression, and improves cognitive function, it helps prevent viral infections and symptoms of ulcerative colitis. B Infantis is a subspecies which has been shown to protect against polio. B Longhum protects the lungs from infection. It prevents food born illness and prevents candida from becoming pathogenic. It reduces symptoms of gout and prevents inflammation. It prevents allergies and celiac disease. It reduces endotoxins and prevents fatty liver disease. It increases biotin levels. It reduces bloating in the gut especially ssp Infantis. B Longhum improves sleep and prevents anxiety. Reduces depression caused by stress by reducing cortisol. It prevents liver disease and produces B12 and Folate.c It improves bone health and fights cancer. It decreases TH1 and TH17 cytokines. B Longhum also reduces aggressive behavior. B Longhum improves nutrient absorption. Reduces histamines. B longhum stimulates the vagal nerve.
B Infanis increases tryptophan. Decreases bloating. Bifidobacterium Longhum also helps prevent lactose intolerance. It detoxes serotonin metabolites. It decreases adrenalin levels and restores the HPA axis. It reduces inflammation and increases lifespan. It prevents ulcers. It helps prevent lactose intolerance. Increases IL-10 and IL-1B which seems contridicting but IL-1B is needed to increase intestinal motility. IL-10 keeps IL-1B from causing inflammation and immune issues.
Bifidobacterium Infantis increases tryptophan, serrotonin and GABA precursors. Helps prevent inflammatory bowel diseases. B Infantis increases T regulatory cells which helps keep the immune system balanced. B Infantis promotes the production of IgA which is usually low in those with malabsorption and inflammatory bowel disease.
B Infantis reduces histamines. B infantis decreases intestinal bloating, pain and gut distention (enlarged or inflammed). B Infantis increases tolerance to pain. B Infantis has been shown to protect the health of the pancreas.
Bifidobacterium Breve helps protect from food born pathogens and diarrhea. It also helps prevent allergies. Has been shown to improve intestinal health. Reduces anxiety and improves cognition. Reduces histamines. It helps the body absorb nutrients. It reduces bloating and inflammation. Prevents obesity.
Bacteroides Thetaiotaomicron secrete natural antibiotics which keep the gut balanced. It is also responsible for innate immunity in the intestines. It reinforces the mucous membrane. It reduces inflammation. It also helps break down carbohydrates. Prevents constipation and improves bile production. But high levels can promote Clostridium infection.
Bacteroides Ovatus helps break down carbohydrates and feeds other commensal bacteria. It breaks down the most difficult fiber that none of the other microbiota can.
Lactobacillus Rhamnosus helps prevent anxiety and depression by upregulating GABA. L Rhamnosus also prevents lactose intolerance, asthma and allergies. It also prevents skin rashes and eczema. L Rhamnosus also prevents urinary infection. Helps restore normal vaginal and bladder microbiome. Helps prevent candida and fungul infections. Helps prevent inflammatory bowel diseases. Reduces oxalates. Prevents food sensitivities. Breaks down histamines. Reduces endotoxins and inhibits biofilm formation. It simulates phagocytosis which helps fight infection. Phagocytosis is inhibited in those with immune deficiency. Reduces histamines. Rhamnosus improve bowel movements by increasing intestinal motility. Has been shown to prevent chronic fatigue.
Lactobacillus Acidophilus prevents excessive weightloss and reduces inflammation. Has been shown to reduce symptoms of arthritis. L Acidophilus increase CB2 receptor expression. Prevents urinary and bladder infection and helps keep the ph of the bladder and intestines balanced. Helps prevent candida and fungul infections. Helps prevent inflammatory bowel diseases. Prevents celiac disease, milk allergies and food sensitivities. L acidophilus helps with FODMAP intolerance and has been shown to reduce SIBO. It reduces pain by stimulating the opioid receptor. Helps prevent acne. Helps prevent allergies and food intolerances. Helps prevent infection in the bladder and intestines by balancing the ph. If we become too alkaline it promotes pathogen growth. It also prevent vaginal infections. Has been shown to protect the health of the pancreas. Increases IL-10.
Mycobacterium Vaccae helps prevent brain inflammation, anxiety and depression. It also improves cognitive function. It is found in healthy soil in forest among decaying folage. Supposedly eating leaves from a plant can give you this. It induces a strong T cell response when first establishing in the body and then slowly declines as it gets established. Once established it increases T regulatory cells. It helps fight tuberculosis.
Almost all bifidobacterium prevent depression and anxiety but can cause weight loss so those who are under weight my want to be cautious in taking these in excess. Red Wine increases Bifidobacterium. The bifidobacterium also decreases adrenalin levels.
Sophora has been found to increase most of the bacteria that prevent anxiety and depression.
Lactobacillus Iners promotes vaginal dysbiosis so should be avoided , high levels can cause miscarriage. It increases risk of contracting sexually transmitted diseases. One good thing about it is it prevents HPV infection.
Lactobacillus Jensii reduces the risk of contracting sexually transmitted diseases and renal infection. It helps with the break down of milk. It reduces the population of other Lactobacillus which can help with obesity. Lactobacillus Jensii produces chemicals that inhibit HIV. Helps restore normal bladder and digestive microbiome. Helps protect from HPV infection. It helps maintain the proper PH of the intestines and the bladder.
Lactobacillus Crispatus causes weight loss in those who are obese and protects from infections in the renal system, bladder and prevents sexually transmitted diseases. It helps keep the ph of the bladder and digestive system balanced. Helps restore normal gut and bladder microbiome. Helps protect from HPV, HIV and many other types of infection. It prevents vaginal odor.
Lactobacillus Johnsii requires purines to survive so needs purine producing commensals or purines consumed in the diet. It produces natural antibiotics that protect the gut from infection and prevent H Pylori and Candida from becoming pathogenic. It has been shown to thicken the mucous membrane in the gut and helps heal peptic ulcers. It restores the proper number of IgA, IgG and CD8+ cells which are low in tick born illness and inflammatory bowel and malabsorption disorders. It helps prevent skin lesions. It has been shown to reduce diabetes and even reverse it in some. L Johnsii prevents insulin resistance and allergies. It also prevents vaginosis. Those with interstitial cystitis or high TH17 levels would want to avoid this one because it increases TH17 levels along with COX2 which is high in interstitial cystitis, psoriasis, and lupus. It would help restore nutrient absorption in those with malabsorption.
Lactobacillus Kefiranofacians is found in kefir and fermented milk. It prevents cavities and biofilm formation. It does not survive in the gut long so you would have to gargle with it. It also helps with constipation. It stimulates the intestines to produce more mucin increasing the mucous membrane in the gut which helps with colitis. Those with high TH1 levels would want to avoid it because it increases TH1 levels.
Lactobacillus Kimchii increases phagocytosis which would not be good in those with a hyper immune system but would help those who have an inhibited immune system. It is found in kimchi. Kimchi also contains Lactobacillus Sakei which inhibits biofilm formation.
Lactobacillus Plantarum has potent antioxidant abilities. It helps maintain proper intestinal permeability and helps with malabsorption disorders. It produces antimicrobials that fight gram positive and gram negative bacteria. It accelerates gut repair. It helps with chron’s and inflammatory bowel disease. It reduces skin rashes and eczema. It has been shown to help with diabetes. It prevents diabetes and high blood pressure. L Plantarum also prevents biofilm formation. L Planatarum increases muscle mass, muscle strength and endurance. Helps prevent candida and fungul infection. Helps prevent inflammatory bowel diseases. Reduces oxalates. Breaks down histamines. L Plantarum improves intestinal epithial health. It produces L-Lysine which improves our bodies ability to use calcium. It has been shown to improve mental health. It is improves the absorption of nutrients into the body. It helps remove toxins from the body.
Lactobacillus Pontis increases NOD2 which fights viruses but is not good for those with inflammatory diseases or inflammatory bowel disease.
Bifidobacterium Adolenscentis helps break down milk proteins, promotes normal bowel movements, produce many of the same vitamins that most Bifidobacterium produce which includes B1, folate, B12, biotin and riboflavin. It also produces vitamin C but not in high enough amounts to provide the body with adequate levels of vitamin C. It like most Bifidobacterium dephosphoralizes phytic acid. Which prevents the antinutrient effect of Phytic Acid. If a person is low in Bifidobacterium then phytic acid will deplete their bodies of nutrients. It helps fight Coxsackievirus and other viruses. If a person is deficient in Bifidobacterium they are more prone to Norovirus infection. It along with most bifidobacterium prevents obesity, cardiovascular disease and diabetes.
Streptococcus Salvarius prevents infection in the throat nose and mouth. It also produces natural antibiotics that kill harmful bacteria. Prevents food allergies. It also prevents lung infection.
Streptococcus Mitis prevents infection in the throat nose and mouth.
E Coli Nissle prevent E Coli infection, prevents halitosis, helps prevent infection in the mouth , throat and nose. Helps with inflammatory bowel diseases. E Coli Nissle protects us from it’s pathogenic cousins. It also protects from other food born illness.
Lactobacillus Salvarius prevents cavities and prevents biofilm formation and prevents dental plaque. Helps prevent fungul infection and candida.
Lactobacillus Coagulans (Lactobacillus sporogenes ) helps prevent inflammatory bowel diseases. Has been shown to prevent diabetes. It enhances protein absorption and increase muscle healing, improves muscle recovery time and increases endurance. It inhibits fibrosis which would help with fatty liver disease and COPD. It increases butyrate producing bacteria. It decreases abdominal pain. It requires oligosaccharides. It improves bowel motility which prevents constipation. It reduces symptoms of inflammatory bowel diseases. It helps improve feeding tolerance. In other words it helps restore your appetite.It prevents parasite infections and has been shown to protect against the flu and adenovirus. It has been shown to reduce vaginosis. It also protects from many pathogens that cause diarrhea.
Lactobacillus Gasseri prevents halitosis. Helps restore normal bladder and gut microbiome. Reduces oxalates and histamines. Helps protect from HPV infection. It reduces menstrual pain. Reduces allergies and asthma. Helps break down phytic acid preventing it from being and antinutrient.
Bifidobacterium Animalis prevents food allergies and reduces oxalates. Prevents constipation speeds up food transit time. It prevents bloating, nuero inflammation, oxidative stress, and increases serrotonin, dopamine and norepineprhine by inhibiting MAO activity. Prevents obesity and anemia. It protects from polio and rotavirus. It reduces the length of the flu and prevents lung infection. I reduces allergies but increases TH1 levels. It reduces inflammation and increases T regulatory cells. It increases good gut microbes and decreases the bad. Improves digestive health. Prevents diarrhea and constipation. Helps with colitis and inflammatory bowel disease. It enhances immunity. It helps prevent celiac disease. It degrades oxalates. It improves nutrient absorption. It reduces stress hormones helping to reduce anxiety.
Bifidobacterium Adolescentis prevents food allergies and reduces oxalates. It prevents diarrhea from pathogens and prevents constipation. It helps protect from the rotavirus. Prevents asthma. Inulin increases B Adolescentis. It is fed by F Prausnitzii. It helps reduce fatty liver disease.
Akkermansia Muciniphila helps prevent obesity and helps to produce short chain fatty acids and is usually low in those will malabsorption issues. Deficiency in Akkermansia Muciniphila can lead to diabetes. Akkermansia Muciniphila also protect us from inflammation. It is important in homeostasis in the gut. It also produces oligosaccharides which feed our good gut microbes. It helps produce SCFA which are needed by the body and our microbiome. It helps maintain the shape and health of the mucous membrane in the gut. Low levels of Akkermansia Muciniphila results in a thinner mucous membrane making us more prone to infection and inflammatory bowel diseases. A deficiency in Akkermansia can result in appendicitis. Arabinoxylin, Inulin , fructoligosaccharide, oligofructose increases Akkermansia. Polyphenols in pomegranate, grapes, grape seed extract , and navy beans increase Akkermansia. Cod liver oil also increases Akkermansia. When there is a wound in the gut Akkermansia will go to the site of the wound and signal the body it needs to repair that area. This is one of the most important microbes for gut health. If we are deficient in it bacteroidetes leves get to high, bile production becomes inhibited and our bodies do not secrete pancreatic enzymes. I discuss the consequences of high bacteroidetes levels at the end of this post. Increased CB1 receptor activation reduces Akkermansia, inhibiting CB1 receptor increases Akkermansia but inhibiting CB1 increases depression and anxiety. Akkermansia needs Faecalibacterium Prausnitzii and vice versa. There is research showing if Akkermansia levels get too high it can increase zonulin levels so though it is a key mcirobiota in the regulation of our health homeostasis should always be the goal.
Clostridium Butyricum help prevent many food born pathogens, helps produce short chain fatty acids, it prevents diabetes and helps keep the sulfur digesting and ammonia producing bacteria like Bacteroidetes and Firmicutes from getting too high. If those are high a person can develop diabetes, malabsorption from inhibited bile production and inflammation. It prevents insulin resistance. Clostridium Bytyricum also protect from bartonella.
Faecalibacterium Prausnitzii Faecalibacterium a deficiency can lead to irritable bowel syndrome. Produces butyrate from fiber. A deficiency in F Prausnitzii can lead to asthma, obesity, depression ,Chohn’s disease and inflammatory bowel diseases. A deficiency in this can lead to high TH17 levels resulting in psoriasis. Those with cardiovascular disease and Type 2 diabetes are usually low in F Prausnitzii. Akkermanis Municiphila needs it and vice versa. Prevents inflammation.
It also helps balance the immune system. It needs Akkermansia to thrive. Oligosaccharides increase F. Prausnitzii. It prevents celiac disease. It induces IL-10. It is necessary for fatty acid oxidation. It produces butyrate. It produces Salicyclic acid which is what they make aspirin from. It produces raffinose a type of oligosaccharide that decreases gut permeability which prevents leaky gut. It along with other commensals form biofilms that help protect and heal the gut. Decreases zonulin which preserves the integrity of the tight protein layer. If zonulin levels get too high a person will develop lactose, gluten and gliadin intolerance.
Enterococcus faecium prevents listeria infection and prevents infection from it’s pathogenic cousins. There is a human species which is non pathogenic and an animal species and the animal species is pathogenic to humans. I view this one as a dangerous pathogen even though it is used in probiotics when the body is weak it can make a person very very ill.
Weissella Cibaria also prevents halitosis, cavities, and this one also reduces skin lesions. It also reduces Hydrogen Sulfide and inhibits biofilms. Weisella Cibaria is found in kimchi and fermented milk. It prevents inflammation caused by endotoxins. It also prevent Nirtic oxide induced by endotoxins and promotes the healing of intestinal epithelial cells. It inhibits biofilm formation of pathogenic microbes.
Preovotella Histicola reduces arthritis, increases T regulatory cells and IL-10 which help keep the immune system balanced and reduces TH17. These are often a problem in those with tick born illness or mycoplasma infection. Reduces allergies.
Collinsela Aerofaciens increases intestinal PH which prevents pathogens and keeps candida and H Pylori in their commensal forms. It has been shown to prevent irritable bowel syndrome. It requires maltose, lactose or glucose. Whole grains increase C Aerofaiens. It prevents arthritis by inhibiting IL17.
Lactobacillus Bulgaris increases life span. Helps maintain the proper PH of the bladder and intestines which prevents infection and dysbiosis. Prevents the bladder and intestines from becoming alkaline. If they become alkaline candida and H pylori will go from commensal to pathogenic. It balances the microbiome in the digestive system. It also helps prevent lactose intolerance. It helps prevent liver disease and has been shown to reduce the risk of getting the common cold. It prevents dermatitis and eczema. It has been shown to help with inflammatory bowel disease. It prevents tooth decay and also prevents infection in the intestines and prevents pouchitis. It prevents constipation. It helps neutralize many toxins.
Odoribacter Splanchnicus a loss of Odoribacter causes a loss of SCFA availibility which leads to inflammation and low glucose levels. Deficiency in O Splanchnicus can lead to hypertension and diabetes. Low levels of O Splanchnicus can also lead to interstitial cystitis. It is important for absorption of nutrients and in maintaining a healthy gut. Has been shown to prevent atherosclerosis. Requires glucose, galactose, salicin, trehalose, arabinose, fructose or mannose. Inhibits many of the sulfur digesting bacteria that can cause high sulfite levels and high hydrogen sulfide levels. O Splanchnicus also breaks down phytoestrogens found in many plants.
Lactinifactor Longoviformis breaks down phytoestrogens found in many plants.
Arthrobacter Agilis it produces carotenoids which the body can convert to vitamin A. It reduces the risk of Parkinson’s disease. They degrade many pesticides. It prevents fungus infection but I am not comfortable with Arthobacter species because some of them produce antifreeze and I cannot find any research to show with this one did or not. I do not feel this is a safe probiotic and I have not spoken to anyone who had used it.
Eubacterium Halli it produces butyurate from acetate, glucose and lactate. It produces vitamin B12. It is important for homeostasis in the body and produces SCFA. It improves insulin sensitivity and normalizes blood glucose levels. It cannot process complex carbohydrate and needs bifidobacterium to exist. It makes some carcinogens harmless.
Arthrobacter Globiformis uses sugar as it’s main source of food. It uses sugar and ammonia. It’s byproducts are nitrogen and hydralimine. I do not know the health effects of these but it can break down many toxins in the enviroment but I do not feel comfortable using these as a probiotic I have not seen enough research on the use of this. Their are many of the Arthrobacter species that are used for probiotics and almost all of them break down some form of toxin but I cannot find research on their safety or effectiveness.
Pediococcus acidilactici it has been shown to reduce gastrointestinal distress. It prevents infections by food born pathogens and has been shown to stop bloody diarrhea. It also prevents constipation. Has been show to stop excessive vomiting. It has been shown to fight pathogenic parasites. It increases IL-10 and T regulatory cells which would balance the immune system. It has also been shown to fight fungal infections.
Most Bacillus species convert genotoxic substances to non toxic substances. Bacillus species are found in the soil and in humans. Some can be pathogenic. Man soil based bacteria improve nutrient absorption. There are other strains of Bacillus species but I did not list them because they have the ability to produce endotoxins. Bacillus species help break down food better which improves nutrient absorption. They should be taken with food or they do not get established well. Many of the Bacillus species secrete amylase and lipase. Amylase helps break down carbohydrates and lipase breaks down fats. Bacillus species may help those with malabsorption issues. Bacillus species detox a lot of toxins including mycotoxins found in fungus and molds. Mycotoxins can cause birth defects, sterility, it can increase estrogen levels. Most bacillus species can detox mycotoxins zearalenone, and aflatoxin but other mycotoxins that get broke down are species specific. Most Bacillus species train the immune system on how to fight pathogens. Most bacillus species reduce the risk of diabetes and cardiovascular disease. Most bacillus species help prevent leaky gut and promote healing of the gut.
Bacillus Lacterosporous is found in soil and humans. It fights fungus. Helps prevent leaky gut. It also fights mycoplasma infection. I have not seen studies on the effectiveness or safety of this microbe.
Bacillus Firmis promotes the differentiation of B lymphocytes to Ig producing and secreting cells. It stimulates the repair of blood vessels.
Bacillus Clausii stimulates the production of IgA but requires GALT. Prevents lung infections has been used successfully to treat those who get recurrent respiratory infections. Has also been used successfully to treat acute diarrhea. Studies show it is safe for human consumption. It protects the body from endotoxins.
Bacillus Licheniformis prevents biofilm formation of pathogens. Prevents the build up of amyloid plaque which contributes to amyloidosis and Alzheimer’s. Amyloid can also destroy beta cells leading to diabetes.
Bacteroides Fragilis promotes the production of GALT.
Phages P. Aerugonosa protect against E Faicalis and many food born pathogens.
Bacteroidetes- there are many species. Meat consumption increases their numbers. If bacteroidetes get too high it can result in weight gain or weight loss from malabsorption. It can cause the inability to absorb fats preventing bile production. It can cause the pancreatic enzymes to become inhibitited and cause phenylketonuria which results in high ammonia levels. It can cause BH4 enzyme deficiency, which can lead to CBS upregulation which can lead to high sulfite levels. This can cause the citric acid cycle to shut down leading to high estrogen levels, high unbound copper levels which farther inhibit the bodies ability to produce bile. This farther increases estrogen levels and levels of unbound copper. This lead to inflammatory bowel disease and malabsorption issues. A person with high Bacteroidetes levels will be high in butyrate and proprianic acid, acetate levels may be high also. They will be low in malanic acid. This also leads to high ammonia levels which causes many other health issues and causes Candida and H pylori to go from commensal to pathogenic. Many with this problem will develop bile acid gird. This also makes someone prone to clostridium infection along with many other pathogens.
If this persist long enough a person can develop interstitial cystitis. This is a common problem in those born by C section and who are formula feed. This also leads to a lot of food intolerances especially milk and glutin along with gliaden. This also can result in thiamine deficiency.
Consuming high amounts of meat can result in high bacteroidetes, methane producing bacteria and increased sulfur digesting bacteria. This can result in high levels of sulfite which will interfere with sulfation and cause many health issues. It can also cause high levels of hydrogen sulfide which will lower blood pressure at first then if levels get high enough it will increase blood pressure and cause severe inflammation. Bile production and production of pancreatic enzyme will become inhibited. High sulfite levels makes a person more susceptable to Salmonella infection. This also inhibits bile production. Butyrate ;producing bacteria help restore bile production.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023267/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953422/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282957/
Another thing that inhibits bile production is extended use of antibiotics. It reduces our good gut microbiome. Muscrarlis Macrophages detect our good gut microbiomes LPS. With the decrease in our good gut microbiome and loss of their LPS to signal muscarlis macrophages dysbiosis occurs which leads to inhibited intestinal motility which causes a loss of bile production and pancreatic enzyme production. Supplementing with commensal LPS has been shown to reduce the symptoms and increase bile flow.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149228/
https://www.cell.com/abstract/S0092-8674(14)00735-1
https://www.cell.com/cell/pdf/S0092-8674(14)00867-8.pdf
A loss of bile production prevents nutrient absorption, the pancreas will not receive the feedback from our intestines and will quit producing enzymes. This result in malabsorption especially of oil soluble nutrients because bile is need to break down fats. This will also cause LDL levels to get low and HDL levels to because high. This imbalance causes HDL to become inflammatory.
A loss of serrotonin producing gut bacteria negatively impact gut health. Tryptophan helps restore gut health. Strange thing is the first three or four days I took tryptophan I had a herx type reaction. It must have been from die off of the bad gut microbes as the good increased. This can lead to damage to the central nervous system.
http://www.pnas.org/content/115/25/6458
https://www.gastrojournal.org/article/S0016-5085(16)34896-X/abstract
Grape seed extract helps restore bile flow.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817264/
If normal bile function is not restored it effects the whole body and can lead to diabetes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073382/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319718/
https://www.frontiersin.org/articles/10.3389/fmed.2017.00163/full
Good articles on reducing candida when it turns pathogenic.
http://www.gestaltreality.com/2013/09/16/how-to-eliminate-candida-biofilms/
https://www.yeastinfectionadvisor.com/candidadiet.html
https://www.theguthealthprotocol.com/wp/the-alkalizing-myth
https://www.selfhacked.com/blog/treat-cure-candida/
https://www.thecandidadiet.com/candida-fighting-foods/
Sometimes people confuse candida with gut dysbiosis.
http://www.ei-resource.org/illness-information/environmental-illnesses/candida-and-gut-dysbiosis/
http://www.holistichelp.net/blog/candida-sibo-or-h-pylori/
If our ammonia levels get high then H Pylori will turn pathogenic to protect itself. When in commensal form it prevents allergies. When H pylori is in pathogenic form it inhibit ghrelin which inhibits digestion and can cause food to sit in the gut and ferment leading to bloating, dybiosis and can inhibit digestive enzymes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888205/
I am not going to cover histamines in this post I will address it in a post on over and under methylators because high and low histamines can cause over or under methylation. Leaky gut, inflammation and status of our immune system can effect methylation.
Now connect this with my other post and you will see that there is no doubt that germ theory and terrain theory are not correct and that our Facebook groups theory “Enveroment and Biome Theory of Health is correct.
Here is a list of my articles on health that will support my case.
Improtance of human photosynthesis in health.
https://iamajuicer.wordpress.com/2018/11/13/importance-of-human-photosynthesis-in-health/
Why so many are experiencing gender identity crisis.
https://iamajuicer.wordpress.com/2018/11/12/why-so-many-are-experiencing-changes-in-gender-identity-why-so-many-children-have-gender-identity-issues/
We can expect diabetes to rise because of all these things.
Diabetes, type 1, type 2 and type 3c.
You can use the above mentioned information to help with hypertension.
https://iamajuicer.wordpress.com/2018/10/28/causes-of-hypertension-and-things-that-may-help/
https://iamajuicer.wordpress.com/2018/10/24/the-truth-about-heart-disease-cholesterol-lowering-drugsand-their-effects-on-mental-health-and-health-of-the-body/
Carditis , hypertension, tachycardia and many other cardiovascular diseases all have a common ties and common solutions.
Compare the above mentioned things and the things that occur within the body and you can make the connection to the gut. This list the many things that can go wrong and how to use nutrients to help heal.
https://iamajuicer.wordpress.com/2018/10/12/my-summarized-notes/
Even allopathic medicine is contributing to the chronic illness and the poor health of modern day society so they are the bad environmental part.
https://iamajuicer.wordpress.com/2018/10/08/cause-of-flaccid-myelitis/
Even our brain gets effected.
https://iamajuicer.wordpress.com/2018/10/02/cant-sleep-feel-disassociated-could-be-your-pineal-gland/
https://iamajuicer.wordpress.com/2018/09/21/things-linked-to-alzheimers-and-chronic-illness/
Hyper Excitement of NMDA (autism also known as encephalitis)
We are taught that things like genetics are inherited but it is our eating habits and microbiome that gets inherited and they are things that can be changed. Even asthma we are taught is inherited but I have seen many in my life correct it and live a normal life and never suffer from it again.
https://iamajuicer.wordpress.com/2018/09/22/causes-of-obesity-and-things-that-may-help/
https://iamajuicer.wordpress.com/2018/09/20/why-asthma-is-rampant-now/
We are told that our genes are written and cannot be changed but science is finding that is not true.
https://iamajuicer.wordpress.com/2018/09/02/1303/
Stomach problems they claim runs in families but it is actually the gut microbiome they inherited and can be corrected.
https://iamajuicer.wordpress.com/2018/09/02/the-microbes-that-help-heal-the-gut/
Things that may help those who have the more difficult digestive problems.
Many have problems with lipid metabolism now days. They claim it is inherited genetics but when I ask people if anyone else in there family suffered from it they say no. So how can it can they inherit something no one else ever experienced in their families?
https://iamajuicer.wordpress.com/2018/08/21/things-that-may-help-with-lysosomals-storage-disease/
The above mentioned things should help with liver disease also.
https://iamajuicer.wordpress.com/2018/08/14/fatty-liver-cirrohsis-thrombosis-and-other-diseases-caused-by-fibrosis/
Many things like COPD are set off by infection or toxins. By now you should know that most supposed pathogens actually help the body unless we have too many toxins or we are lacking a nutrient.
https://iamajuicer.wordpress.com/2018/07/20/things-that-may-help-with-copd/
This is why cancer is so rampant. Cancer is pretty much caused by man and the environment men have created.
https://iamajuicer.wordpress.com/2018/07/29/cancer-what-causes-it-what-may-help-with-it/
What they don’t want you to know about cancer and why so many children are getting it.
Our enviroment and biome can effect our health by causing excess oxidative stress.
https://iamajuicer.wordpress.com/2018/08/02/oxidative-stress-the-antioxidant-systems-and-how-they-effect-our-health/
Now you can see why tick born illness is rampant. Thing that usually would not usually effect man is now causing illness. Infection indicates there is a nutrient deficiency or enviromental toxin or enviromental biome issue. Something is out of balance. Man is viewing symptoms like cancer, diabetes, and mental illness as the cause and they are symptoms of underlying problem.
https://iamajuicer.wordpress.com/2018/06/17/vaccinations-spread-and-cause-disease/
Cause of flaccid myelitis.
https://iamajuicer.wordpress.com/2018/07/21/things-they-would-rather-you-did-not-know-about-lyme/
Vaccination are one of the biggest contributors of modern illness.
Identifying vaccine injury and it’s cost to society.
This is why detoxing is so important now days. Even our food has become toxic. Organic helps reduce the impact of mans destruction of our environment and the human and planetary biome.
https://iamajuicer.wordpress.com/2018/07/14/detoxing-we-need-it-now-days/
https://iamajuicer.wordpress.com/2018/07/23/how-toxic-is-your-food/
Genetically modified foods destroy our health glyphosate and glufosinate add to the toxicity.
They know their science is fake so they use every tactic they can to hide that fact.
Tactics used by corporate science to deceive people into not asking questions.
If you have read this then by now it have figured out it is not your genes but your enviroment, inner and outer biome and not your genes that effect your health.
It’s not your genes it is your gut microbiome.
Histamine homeostasis is very important in fighting chronic illness.
The effect of high or low histamines.
Since modern day illness is causing chronic illness by destroying our gut we need to work on restoring it to heal. Leaky gut causes endotoxemia. I listed in the microbe list above which ones reduce endotoxins. It also causes high oxalates so you will have to work on reducing them.
Leaky Gut, Oxalates and more supplement information.
Dealing With Endotoxemia or Sepsis.
All these things are types of autoimmunity and we need to restore our immune system back to homeostasis.
Autoimmunity what causes it and things that may correct it.
Interstitial cystitis and vaginitis are some of the worst autoimmune disorders to deal with because our modern day environment makes it difficult to acheive homeostasis in the areas effected.
Causes of vaginitis/thinning or atrophy of the vaginal walls and things that may help.
Healing Interstitial Cystitis.
Constipation can lead to inflammatory bowel disease and inhibited bile productin and is caused by an imbalance in our gut microbiome. It can lead to chronic illness.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951383/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872693/
I noticed that those with dysbiosis had issues when the consumed or took tryptophan. This study suggest that SERT might be upregulated in dysbiosis which wold explain why tryptophan made them worse. Sert is the serotonin transporter.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583244/
https://www.nature.com/articles/s41598-017-10835-8
There are those who say but things like H Pylori cause illness. So how could that prove what your are saying. H Pylori just like many of our beneficial bacteria only cause problems when something has changed to cause it to occur. They say yeah but there is strains that are pathogenic and strains that are not. Well the biggest part of the population is believe to have the supposed pathogenic strain of H Pylori. So you have to ask why doesn’t everyone get gastric ulcers?
https://www.frontiersin.org/…/10…/fmicb.2018.00609/full
Even our good gut bacteria can cause illness if we have digestive problems.
https://www.sciencedirect.com/science/article/pii/S1198743X14618838
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490230/
Our food and water is so toxic now it has a negative impact on our guts. The crazy thing is some of these toxins are found in vaccines so imagine what they are doing when they are being directly shot into peoples blood streams.
https://www.mdpi.com/2076-2607/6/2/53/htm
Desulfibrio species digest sulfur which produces H2S. If H2S levels get too high it can cause many health issues. B Thetamiomicron free sulfur which feeds Desulfibrio species. They cannot free it themselves. Mercury and lead increase Desulfibrio species. Excess H2S can lead to constipation. This is why high levels of Akkermansia and Desulfibrio results in inflammatory bowel diseases, gall stones and many other diesease. Not getting enough fermentable carbohydrates increases sulfur digesting microbes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1233901/
https://www.ncbi.nlm.nih.gov/pubmed/26491870
https://www.ncbi.nlm.nih.gov/pubmed/19709217
https://www.tandfonline.com/doi/abs/10.3109/00016357.2013.770163
https://www.frontiersin.org/articles/10.3389/fmed.2017.00163/full
It is listed among the bacteria that increases the risk of heart disease and diabetes.
https://www.ncbi.nlm.nih.gov/pubmed/29800124
Glycomacropeptide found in whey protein and fermentable fiber reduces sulfur digesting bacteria. Fermentable fibers are pectin, Beta-glucan found in mushrooms and oatmeal, guar gum, inulin and oligosaccharides. If a person is not used to getting them they will have to ease into them. Until the body is used to getting them they will cause bloating and gas. As the body gets used to them the symptoms will slowly decrease. Psyllium should be avoided it has been found to make the symptoms worse.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593820/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190755/
Those with inflammatory bowel and gut dysbiosis usually have high levels of H2S being produced by their gut microbes. Fructooligosaccharide and Resistant starch decreases H2S but psyllium increases it so psyllium should be avoided.
https://www.ncbi.nlm.nih.gov/pubmed/29561196?fbclid=IwAR3wOZijtOeO0NF_4liAPIZwHwiK-bAqMn4IsPFQNQ1PbkuJU0cydwzuFs0
Strange lactulose is in raw milk increases Hydrogen production but it helped me.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201941/
Now we do not want to completely rid ourselves of the H2S producing microbes because they are needed to keep us health. We want to try and restore homeostasis. For those with high sulfur digesting bacteria a glass of non sulfur wine may help.
https://www.fasebj.org/doi/abs/10.1096/fasebj.31.1_supplement.855.3
High H2S levels can effect sulfation by inhibiting sulfur detoxification. It can even effect the antioxidant system. High H2S levels also inhibits nNOS. It can be countered by increasing NADPH and BH4.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040266/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210431/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599001/
Methane producing bacteria can also cause constipation leading to inflammatory bowel diseases. Those with high methane levels usually suffer from nausea, will feel full and bloated, may experiencing vomiting. They will have milk intolerance because the sugars in milk feed methane producing bacteria. They will experience bouts of severe depression. Constipation causes bile to become inhibited resulting in similar health problems as those who have high sulfur digesting bacteria.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987281/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544731/
For those with dysbiosis from high methane producing bacteria should not drink alcohol it can make it worse.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544731/
Those with methane producing dysbiosis need to avoid fermentable carbohydrates and lactulose found in milk products. I know those feed the good gut bacteria but they also feed the gut bacteria that produce hydrogen which feeds the methane producing bacteria.
https://bellalindemann.com/treat-constipation-causing-methane-sibo/
Methane producing bacteria out compete Sulfur digesting bacteria for H2 unless sulfate is present.
https://gut.bmj.com/content/32/12/1498
This surprised me the same microbes that feed the sulfur digesting bacteria also feed the methane producing bacteria. Firmicutes and bacteroides is high in both types of dysbiois.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC442992/
This is another commonality that I have found with those who have inflammatory bowel from too many sulfur digesting and too many methane producing is they both had low bacteroides fragilis levels. I am cautious recommending this because if level get too high it can cause health problems.
https://www.hindawi.com/journals/bmri/2016/5828959/
Bacteroides vulgatis and Bacteroides Dorei are usually low in both types of inflammatory bowel and can lead to cardiovascular disease. Seems there is an easy fix for this. Eating walnuts. This should help Both types of inflammatory bowel issues.
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.033714
https://www.fasebj.org/doi/abs/10.1096/fasebj.29.1_supplement.1006.1
Excessive methane production or excessive hydrogen production can cause malabsorption. So both should be measured in those with malabsorption issues.
http://iopscience.iop.org/article/10.1088/1752-7155/7/2/024001/meta
Alcohol consumption should be avoided with methane producers because it increases methane.
https://www.nature.com/articles/s41598-017-07637-3
The gut microbes are dramatically different in those with NAFLD.
When you look at studies on cirrhosis of the liver. The things that help NAFLD seem to be things that improve oxidation which leads me to believe they are low oxidizers. But alcohol liver disease seems more inflammatory. But they both have links to the gut. Very interesting report.
https://www.mdpi.com/2072-6643/10/10/1457
If a person craves sugar it may mean their lactobacillus acidophilus levels are too high.
Microbes interact with our mitochondria including our gut microbes.
https://academic.oup.com/femspd/article-pdf/74/1/ftv096/10749982/ftv096.pdf
Chemicals in our environment and those pushed by the pharmaceutical industry change our external environment which is killing the commencile pathogens that keep the pathogenic ones in check. This is a common theme now days. When someone gets and infection they either have high toxin levels, were taking allopathic medications or had a nutrient deficiency. All those effect our commensals that protect us from their pathogenic cousins.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510460/
Some functional food that help straighten the gut out.
https://www.frontiersin.org/articles/10.3389/fmicb.2017.02146/full
https://www.frontiersin.org/articles/10.3389/fvets.2018.00166/full
Probiotics and their effects on autoimmune disease.
https://www.mdpi.com/2072-6643/10/10/1537/htm
And yes autoimmunity can lead to mental illness that is why vaccine damage the brain.
https://onlinelibrary.wiley.com/doi/full/10.1111/imm.12943
Using the information on probiotics above you can see the connection between the gut and arthritis.
https://www.mdpi.com/1422-0067/19/9/2508
Those with Trimethylaminuria may be deficient in sulfur digesting bacteria. This would reduce TMAO in the plasma. Could Trimethylaminuria be from a deficiency in methane producing and enterobacteriaceae?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239492/
https://www.nature.com/articles/ismej201772
https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-018-0461-0
How microbes effect neurological stress.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736941/
This report shows why it is important to address leaky gut and gut dysbiosis. It can damage the kidneys.
https://www.mdpi.com/2072-6651/10/7/300
Methylation issues must be addressed before you can get your gut to heal.
Overmethylators
http://www.mensahmedical.com/common-symptoms-of-overmethylation/
Undermethylators.
http://www.mensahmedical.com/common-symptoms-of-undermethylation/
IL-22 is needed to protect us from pathogens and to stimulate FUT2. If we are deficient in certain gut microbiota that stimulate FUT2. We will have immune issues and gut dysbiosis because FUT2 keeps our good gut microbes health.
http://www.traceyreed.ca/blog/2016/4/12/fut2s-role-in-gut-healths-role-in-gut-health
https://www.sciencedirect.com/science/article/pii/S0022283615006051
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774895/
ILC3 is needed for our gut microbiome to communicate with the body to increase FUT2. ILC3 is secreted by our gut microbiome.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774895/
http://science.sciencemag.org/content/345/6202/1254009.long
https://www.researchgate.net/publication/260808789_Microbiota-Dependent_Crosstalk_Between_Macrophages_and_ILC3_Promotes_Intestinal_Homeostasis/download
Oligosaccharide helps if someone is deficient in FUT2
https://nutritionfacts.org/2013/01/10/boosting-gut-flora-without-probiotics/
https://www.newhope.com/ingredients/oligosaccharides-revealing-more-health-benefits
If the immune system is out of balance IL-22 can be upregulated causing illness. This is why the microbiome that increase T regulatory cell and decrease inflammation are important and reducing endotoxins is also important.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710696/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117408/
https://www.dovepress.com/profile-of-interleukin-22-in-gut-mucosal-health-and-disease-peer-reviewed-fulltext-article-IJICMR
https://www.sciencedirect.com/science/article/pii/S0925443914001513
IBS with constipations is IBS-C, IBS with diarrhea is IBS-D, IBS that is mixed is IBS-M. Most I have met have IBS-C and it is why I post on constipation a lot.
5-HT(serotonin) helps regulate gut motility.
https://www.ncbi.nlm.nih.gov/pubmed/25954931
Lactobacillus Rhamnosus GG increases 5-HT uptake .This would help those who have diarrhea but will decrease motility adding to the problem for those who have constipation type inflammatory bowel. 5-HT plasma levels in those who have diarrhea is low and in those who have consipation it is high. E Coli Nissle 1917 increases 5-HT bioavailibility. F Prausnitzi A2-165 down regualates 5-HT which may help those with constipation type inflammatory bowel. Some of the studies were done poorly but there is useful information in them. They also list some microbiota that can improve motility.
https://www.wjgnet.com/1007-9327/full/v24/i3/338.htm
https://www.wjgnet.com/1007-9327/full/v22/i36/8137.htm
https://www.ncbi.nlm.nih.gov/pubmed/28871143
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583244/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951383/
There are three forms of IBS. IBS-D involves diarrhea, IBD-C involves constipation and IBD-M is a mix of both. Serotonin regulates gut motility and enzyme secretion. Damage to the digestive system and leaky Gut effects GLP-1’s ability to sense nutrients. 5-HT is involved in the regulation of gut motility and enzymes. It depends on GLP-1 and serotonin. Gut our gut bacteria regulate serotonin and GLP-1. The type of microbes involved in the dysbiosis determines which type of IBS a person will suffer from.
https://www.sciencedirect.com/science/article/pii/S2212877818301406
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263172/
Healing the brain and addressing high zonulin levels and restoring the gut bacteria and addressing neurological issues are necessary to restore proper gut brain communication. Inflammation must also be addressed.
https://www.frontiersin.org/articles/10.3389/fnins.2018.00049/full
http://www.mdpi.com/1424-8247/11/3/63/pdf
How metabolic issues disrupt the communication with our gut.
http://jem.rupress.org/content/213/10/2129
Our genes communicate with our gut bacteria.
http://jem.rupress.org/content/215/8/1965.long
http://cancerres.aacrjournals.org/content/77/8/1783
Our genes can be altered by our environment and what we put in them.
https://iamajuicer.wordpress.com/2018/09/02/1303/
A good article on the immune system and our gut.
https://www.karger.com/Article/FullText/484687
Lee's Stuff 
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